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At the level of individual neurons, various coding properties can be inferred from the input-output relationship of a cell. For small inputs, this relation is captured by the phase-response curve (PRC), which measures the effect of a small…

神经元与认知 · 定量生物学 2026-01-14 Janina Hesse , Susanne Schreiber

Regular firing neurons can be seen as oscillators. The phase-response curve (PRC) describes how such neurons will respond to small excitatory perturbations. Knowledge of the PRC is important as it is associated to the excitability type of…

神经元与认知 · 定量生物学 2010-01-05 Benjamin Torben-Nielsen , Marylka Uusisaari , Klaus M. Stiefel

Phase response curve (PRC) is an extremely useful tool for studying the response of oscillatory systems, e.g. neurons, to sparse or weak stimulation. Here we develop a framework for studying the response to a series of pulses which are…

数据分析、统计与概率 · 物理学 2017-09-13 Vladimir Klinshov , Serhiy Yanchuk , Artur Stephan , Vladimir Nekorkin

The phase-response curve (PRC) is an important tool to determine the excitability type of single neurons which reveals consequences for their synchronizing properties. We review five methods to compute the PRC from both model data and…

定量方法 · 定量生物学 2010-03-29 Benjamin Torben-Nielsen , Marylka Uusisaari , Klaus M. Stiefel

The phase response curve (PRC) is an important measure representing the interaction between oscillatory elements. To understand synchrony in biological systems, many research groups have sought to measure PRCs directly from biological cells…

定量方法 · 定量生物学 2015-08-03 Kazuhiko Morinaga , Ryota Miyata , Toru Aonishi

The phase sensitivity curve or phase response curve (PRC) quantifies the oscillator's reaction to stimulation at a specific phase and is a primary characteristic of a self-sustained oscillatory unit. Knowledge of this curve yields a phase…

适应与自组织系统 · 物理学 2022-12-08 Rok Cestnik , Erik T. K. Mau , Michael Rosenblum

We examine the effect of the phase-resetting curve (PRC) on the transfer of correlated input signals into correlated output spikes in a class of neural models receiving noisy, super-threshold stimulation. We use linear response theory to…

神经元与认知 · 定量生物学 2015-05-13 Andrea K. Barreiro , Eric Shea-Brown , Evan L. Thilo

Brain rhythms emerge as a result of synchronization among interconnected spiking neurons. Key properties of such rhythms can be gleaned from the phase-resetting curve (PRC). Inferring the macroscopic PRC and developing a systematic phase…

神经元与认知 · 定量生物学 2022-10-12 Gregory Dumont , Alberto Pérez-Cervera , Boris Gutkin

Synchronized neural spiking is associated with many cognitive functions and thus, merits study for its own sake. The analysis of neural synchronization naturally leads to the study of repetitive spiking and consequently to the analysis of…

神经元与认知 · 定量生物学 2017-07-19 Youngmin Park , Stewart Heitmann , G. Bard Ermentrout

The phase-resetting curve (PRC) describes the response of a neural oscillator to small perturbations in membrane potential. Its usefulness for predicting the dynamics of weakly coupled deterministic networks has been well characterized.…

动力系统 · 数学 2015-05-13 Aushra Abouzeid , Bard Ermentrout

We demonstrate that two key theoretical objects used widely in Computational Neuroscience, the phase-resetting curve (PRC) from dynamics and the spike triggered average (STA) from statistical analysis, are closely related under a wide range…

神经元与认知 · 定量生物学 2007-09-26 G. Bard Ermentrout , Roberto F. Galán Nathaniel N. Urban

The Phase Response Curve (PRC) is a tool used in neuroscience that measures the phase shift experienced by an oscillator due to a perturbation applied at different phases of the limit cycle. In this paper we present a new approach to PRCs…

动力系统 · 数学 2019-07-24 Alberto Pérez-Cervera , Tere M. Seara , Gemma Huguet

A single neuron is known to generate almost identical spike trains when the same fluctuating input is repeatedly applied. Here, we study the reliability of spike firing in a pulse-coupled network of oscillator neurons receiving fluctuating…

适应与自组织系统 · 物理学 2015-05-13 Jun-nosuke Teramae , Tomoki Fukai

In computer simulations of spiking neural networks, often it is assumed that every two neurons of the network are connected by a probability of 2\%, 20\% of neurons are inhibitory and 80\% are excitatory. These common values are based on…

神经元与认知 · 定量生物学 2015-03-06 Hamed Seyed-allaei

The describing function (DF) and phase response curve (PRC) are classical tools for the analysis of feedback oscillations and rhythmic behaviors, widely used across control engineering, biology, and neuroscience. These tools are known to…

系统与控制 · 电气工程与系统科学 2025-11-27 Robin Wroblowski , Rodolphe Sepulchre

Interaction via pulses is common in many natural systems, especially neuronal. In this article we study one of the simplest possible systems with pulse interaction: a phase oscillator with delayed pulsatile feedback. When the oscillator…

混沌动力学 · 物理学 2015-12-14 Vladimir Klinshov , Leonhard Luecken , Dmitry Shchapin , Vladimir Nekorkin , Serhiy Yanchuk

We consider a threshold-crossing spiking process as a simple model for the activity within a population of neurons. Assuming that these neurons are driven by a common fluctuating input with Gaussian statistics, we evaluate the…

神经元与认知 · 定量生物学 2009-06-11 Yoram Burak , Sam Lewallen , Haim Sompolinsky

The computation performed by a neuron can be formulated as a combination of dimensional reduction in stimulus space and the nonlinearity inherent in a spiking output. White noise stimulus and reverse correlation (the spike-triggered average…

生物物理 · 物理学 2007-05-23 Blaise Aguera y Arcas , Adrienne Fairhall

In this paper, we introduce and systematically study, in terms of phase response curves (PRC), the effect of a dual pulse excitation on the dynamics of an autonomous oscillator. Specifically, we test the deviations from a linear summation…

适应与自组织系统 · 物理学 2015-06-16 Giri P. Krishnan , Maxim Bazhenov , Arkady Pikovsky

Perturbation theory is an important tool in the analysis of oscillators and their response to external stimuli. It is predicated on the assumption that the perturbations in question are "sufficiently weak", an assumption that is not always…

神经元与认知 · 定量生物学 2012-01-19 Kevin K. Lin , Kyle C. A. Wedgwood , Stephen Coombes , Lai-Sang Young
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