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To understand the effect of assortative mating on the genetic evolution of a population, we consider a finite population in which each individual has a type, determined by a sequence of n diallelic loci. We assume that the population…

概率论 · 数学 2023-11-30 Alison M. Etheridge , Sophie Lemaire

A model of mutation rate evolution for multiple loci under arbitrary selection is analyzed. Results are obtained using techniques from Karlin (1982) that overcome the weak selection constraints needed for tractability in prior studies of…

种群与进化 · 定量生物学 2013-02-04 Lee Altenberg

The accurate numerical solution of partial differential equations is a central task in numerical analysis allowing to model a wide range of natural phenomena by employing specialized solvers depending on the scenario of application. Here,…

数值分析 · 数学 2022-12-13 Moritz Reh , Martin Gärttner

Consider a system evolving according to an absorbing discrete-time Markov chain with known transition matrix. The state of the system is observed at two points in time, separated by an unknown number of generations. We are interested in…

概率论 · 数学 2015-11-04 Bianca De Sanctis , A. P. Jason de Koning

Kolmogorov complexity and algorithmic probability are defined only up to an additive resp. multiplicative constant, since their actual values depend on the choice of the universal reference computer. In this paper, we analyze a natural…

信息论 · 计算机科学 2010-03-29 Markus Mueller

The purpose of this paper is to develop a new effective approach to higher-order mixing in the semisimple setting. We prove effective exponential mixing of all orders for partially hyperbolic algebraic actions, under a strong spectral-gap…

动力系统 · 数学 2026-05-21 Zhenqi Jenny Wang

Biological tools such as genetic lineage tracing, three dimensional confocal microscopy and next generation DNA sequencing are providing new ways to quantify the distribution of clones of normal and mutated cells. Population-wide clone size…

定量方法 · 定量生物学 2013-11-25 Roshan A , Jones PH , Greenman CD

We solve the Chapman-Kolmogorov equation and study the exact splitting probabilities of the general stochastic process which describes polymer translocation through membrane pores within the broad class of Markov chains. Transition…

统计力学 · 物理学 2015-05-19 Felipe Mondaini , L. Moriconi

We consider a class of nonlocal reaction-diffusion problems, referred to as replicator-mutator equations in evolutionary genetics. By using explicit changes of unknown function, we show that they are equivalent to the heat equation and,…

偏微分方程分析 · 数学 2020-12-16 Matthieu Alfaro , Rémi Carles

Consider a set of N agents seeking to solve distributively the minimization problem $\inf_{x} \sum_{n = 1}^N f_n(x)$ where the convex functions $f_n$ are local to the agents. The popular Alternating Direction Method of Multipliers has the…

分布式、并行与集群计算 · 计算机科学 2014-12-30 Franck Iutzeler , Pascal Bianchi , Philippe Ciblat , Walid Hachem

Consider a haploid population of fixed finite size with a finite number of allele types and having Cannings exchangeable genealogy with neutral mutation. The stationary distribution of the Markov chain of allele counts in each generation is…

概率论 · 数学 2016-12-09 H. L. Gan , Adrian Röllin , Nathan Ross

We analyse conditions for an evolution equation with a drift and fractional diffusion to have a Holder continuous solution. In case the diffusion is of order one or more, we obtain Holder estimates for the solution for any bounded drift. In…

偏微分方程分析 · 数学 2011-04-26 Luis Silvestre

Completion problems, of recovering a point from a set of observed coordinates, are abundant in applications to image reconstruction, phylogenetics, and data science. We consider a completion problem coming from algebraic statistics: to…

统计理论 · 数学 2024-12-04 May Cai , Cecilie Olesen Recke , Thomas Yahl

We study the large population limit of the Moran process, assuming weak-selection, and for different scalings. Depending on the particular choice of scalings, we obtain a continuous model that may highlight the genetic-drift (neutral…

种群与进化 · 定量生物学 2013-01-21 Fabio A. C. C. Chalub , Max O. Souza

The stable allocation problem is a many-to-many generalization of the well-known stable marriage problem, where we seek a bipartite assignment between, say, jobs (of varying sizes) and machines (of varying capacities) that is "stable" based…

数据结构与算法 · 计算机科学 2014-11-26 Ágnes Cseh , Brian C. Dean

In this article, discrete and stochastic changes in (effective) population size are incorporated into the spectral representation of a biallelic diffusion process for drift and small mutation rates. A forward algorithm inspired by…

种群与进化 · 定量生物学 2024-03-11 Lynette Caitlin Mikula , Claus Vogl

We study nonlinear stationary Kolmogorov equations with degenerate diffusion matrices and discontinuous coefficients. The existence of a solution is proved. We propose a new approach based on an integral condition with Lyapunov functions…

偏微分方程分析 · 数学 2026-04-21 Aziz M. Embarek , Dmitry V. Shatilovich

A strong demographic Allee effect in which the expected population growth rate is negative below a certain critical population size can cause high extinction probabilities in small introduced populations. However, many species are…

种群与进化 · 定量生物学 2013-11-22 Meike J. Wittmann , Wilfried Gabriel , Dirk Metzler

In this work, we show that for the martingale problem for a class of degenerate diffusions with bounded continuous drift and diffusion coefficients, the small noise limit of non-degenerate approximations leads to a unique Feller limit. The…

概率论 · 数学 2022-03-01 Anugu Sumith Reddy , Vivek S. Borkar

We formulate an Alternating Direction Method of Mul-tipliers (ADMM) that systematically distributes the computations of any technique for optimizing pairwise functions, including non-submodular potentials. Such discrete functions are very…

计算机视觉与模式识别 · 计算机科学 2017-04-12 Jose Dolz , Ismail Ben Ayed , Christian Desrosiers