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The general Helfrich shape equation determined by minimizing the curvature free energy describes the equilibrium shapes of the axisymmetric lipid bilayer vesicles in different conditions. It is a non-linear differential equation with…
Within the framework of the well-known curvature models, a fluid lipid bilayer membrane is regarded as a surface embedded in the three-dimensional Euclidean space whose equilibrium shapes are described in terms of its mean and Gaussian…
We use theory and numerical computation to determine the shape of an axisymmetric fluid membrane with a resistance to bending and constant area. The membrane connects two rings in the classic geometry that produces a catenoidal shape in a…
The equilibrium shapes of vesicles are governed by the general shape equation which is derived from the minimization of the Helfrich elastic free energy and can be reduced to the Willmore equation in a special case. The general shape…
Consider a homogenous fluid membrane, or vesicle, described by the Helfrich-Canham energy, quadratic in the mean curvature. When the membrane is axially symmetric, this energy can be viewed as an `action' describing the motion of a…
Only some special open surfaces satisfying the shape equation of lipid membranes can be compatible with the boundary conditions. As a result of this compatibility, the first integral of the shape equation should vanish for axisymmetric…
We consider a well known model for lipid-bilayer membrane vesicles exhibiting phase separation, incorporating a phase field with finite curvature elasticity. We prove the existence of a plethora of equilibria, corresponding to…
The shape equation of lipid membranes [Zhong-can and Helfrich(1987) PRL 59 2486] is a fourth-order partial differential equation. Under the axisymmetric condition, this equation was transformed into a second-order ordinary differential…
Lipid bilayer membranes are commonly modeled as area-preserving fluid surfaces that resist bending. There appear to be two schools of thought in the literature concerning the actual area constraint. In some works the total or global area…
We study a model for lipid-bilayer membrane vesicles exhibiting phase separation, incorporating a phase field together with membrane fluidity and bending elasticity. We prove the existence of a plethora of equilibria in the large,…
We present Monte Carlo simulations of an ultra coarse-grained lipid bilayer with different number of lipids on both leaflets. In the simulations, we employ a new method for measuring the elastic parameters of the membrane, including the…
We address the geometric Cauchy problem for surfaces associated to the membrane shape equation describing equilibrium configurations of vesicles formed by lipid bilayers. This is the Euler-Lagrange equation of the Canham-Helfrich-Evans…
The issue of different parameterizations of the axisymmetric vesicle shape addressed by Hu Jian-Guo and Ou-Yang Zhong-Can [ Phys.Rev. E {\bf 47} (1993) 461 ] is reassesed, especially as it transpires through the corresponding Euler -…
We examine the reaction of a homogeneous spherical fluid vesicle to the force exerted by a rigid circular ring located at its equator in the linear regime. We solve analytically the linearized first integral of the Euler-Lagrange equation…
Correctly formulated continuum models for lipid-bilayer membranes present a significant challenge to computational mechanics. In particular, the mid-surface behavior is that of a 2-dimensional fluid, while the membrane resists bending much…
The disk-to-vesicle transition of a fluid membrane with no spontaneous curvature is well described by the competition between edge line and curvature energies. However, the transition of asymmetric membranes with spontaneous curvatures is…
A continuous transformation from a closed vesicle to an open vesicle needs that the area of open hole enlarge from zero. Since the shape equation and boundary conditions of lipid open vesicles with free edges have been obtained, we want…
An elastic sheet lying on the surface of a liquid, if axially compressed, shows a transition from a smooth sinusoidal pattern to a well localized fold. This wrinkle-to-fold transition is a manifestation of a localized buckling. The…
The tensile force along a cylindrical lipid bilayer tube is proportional to the membrane's bending modulus and inversely proportional to the tube radius. We show that this relation, which is experimentally exploited to measure bending…
We present a meshless numerical method for simulating the dynamics of axisymmetric vesicles in a viscous medium. Key innovations include: (1) adaptive reparameterization based on local length scales, reducing the number of required…