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The Fisher-KPP model, and generalisations thereof, is a simple reaction-diffusion models of biological invasion that assumes individuals in the population undergo linear diffusion with diffusivity $D$, and logistic proliferation with rate…

斑图形成与孤子 · 物理学 2022-01-25 Maud El-Hachem , Scott W McCue , Matthew J Simpson

Biological invasion, whereby populations of motile and proliferative individuals lead to moving fronts that invade into vacant regions, are routinely studied using partial differential equation (PDE) models based upon the classical…

组织与器官 · 定量生物学 2020-12-02 Maud El-Hachem , Scott W McCue , Matthew J Simpson

We investigate pattern formation in a two-dimensional (2D) Fisher--Stefan model, which involves solving the Fisher--KPP equation on a compactly-supported region with a moving boundary. By combining the Fisher--KPP and classical Stefan…

生物物理 · 物理学 2022-12-28 Alexander K. Y. Tam , Matthew J. Simpson

This review provides open-access computational tools that support a range of mathematical approaches to analyse three related scalar reaction-diffusion models used to study biological invasion. Starting with the classic Fisher-Kolmogorov…

斑图形成与孤子 · 物理学 2024-04-26 Matthew J Simpson , Scott W McCue

We consider a moving boundary mathematical model of biological invasion. The model describes the spatiotemporal evolution of two adjacent populations: each population undergoes linear diffusion and logistic growth, and the boundary between…

种群与进化 · 定量生物学 2023-09-06 Matthew J Simpson , Nizhum Rahman , Scott W McCue , Alexander KY Tam

While there is a long history of employing moving boundary problems in physics, in particular via Stefan problems for heat conduction accompanied by a change of phase, more recently such approaches have been adapted to study biological…

偏微分方程分析 · 数学 2021-09-23 Scott W. McCue , Maud El-Hachem , Matthew J. Simpson

Single-species reaction-diffusion equations, such as the Fisher-KPP and Porous-Fisher equations, support travelling wave solutions that are often interpreted as simple mathematical models of biological invasion. Such travelling wave…

组织与器官 · 定量生物学 2021-10-04 Maud El-Hachem , Scott W McCue , Matthew J Simpson

We consider a free boundary model of epithelial cell migration with logistic growth and nonlinear diffusion induced by mechanical interactions. Using numerical simulations, phase plane and perturbation analysis, we find and analyse…

斑图形成与孤子 · 物理学 2020-10-05 Ryan J Murphy , Pascal R Buenzli , Ruth E Baker , Matthew J Simpson

We analyse a novel mathematical model of malignant invasion which takes the form of a two-phase moving boundary problem describing the invasion of a population of malignant cells into a population of background tissue, such as skin. Cells…

斑图形成与孤子 · 物理学 2020-09-04 Maud El-Hachem , Scott W McCue , Matthew J Simpson

We consider a reaction-diffusion system of densities of two types of particles, introduced by Edouard Hannezo et al. in the context of branching morphogenesis. It is a simple model for a growth process: active, branching particles form the…

偏微分方程分析 · 数学 2022-04-29 Florian Kreten

We consider a minimal go-or-grow model of cell invasion, whereby cells can either proliferate, following logistic growth, or move, via linear diffusion, and phenotypic switching between these two states is density-dependent. Formal analysis…

偏微分方程分析 · 数学 2024-04-18 Carles Falcó , Rebecca M. Crossley , Ruth E. Baker

We consider a continuum mathematical model of biological tissue formation inspired by recent experiments describing thin tissue growth in 3D-printed bioscaffolds. The continuum model involves a partial differential equation describing the…

组织与器官 · 定量生物学 2021-11-23 Maud El-Hachem , Scott W McCue , Matthew J Simpson

In this paper we study the invasion fronts of spatially periodic monotone reaction-diffusion systems in a multi-dimensional setting. We study the pulsating traveling waves that connect the trivial equilibrium, for which all components of…

偏微分方程分析 · 数学 2025-11-14 Liangliang Deng , Arnaud Ducrot , Quentin Griette

We perform the analysis of a hyperbolic model which is the analog of the Fisher-KPP equation. This model accounts for particles that move at maximal speed $\epsilon^{-1}$ ($\epsilon\textgreater{}0$), and proliferate according to a reaction…

偏微分方程分析 · 数学 2016-11-22 Emeric Bouin , Vincent Calvez , Grégoire Nadin

We give sufficient conditions for the existence of positive travelling wave solutions for multi-dimensional autonomous reaction-diffusion systems with distributed delay. To prove the existence of travelling waves, we give an abstract…

经典分析与常微分方程 · 数学 2015-03-17 Teresa Faria , Sergei Trofimchuk

Standard diffusion equation is based on Brownian motion of the dispersing species without considering persistence in the movement of the individuals. This description allows for the instantaneous spreading of the transported species over an…

斑图形成与孤子 · 物理学 2020-07-13 Pushpita Ghosh , Deb Shankar Ray

This paper is concerned with traveling waves to an diffusive SIR model with delay placed in the diffusion terms as well as nonlinear incidence rate with delay. Using a cross iteration scheme and partial monotone conditions it will be shown…

动力系统 · 数学 2023-10-24 William Kyle Barker

We construct the traveling wave solutions of an FKPP growth process of two densities of particles, and prove that the critical traveling waves are locally stable in a space where the perturbations can grow exponentially at the back of the…

偏微分方程分析 · 数学 2023-08-16 Florian Kreten

For a fixed bounded domain $D \subset \mathbb{R}^N$ we investigate the asymptotic behaviour for large times of solutions to the $p$-Laplacian diffusion equation posed in a tubular domain \begin{equation*} \partial_t u = \Delta_p u \quad…

偏微分方程分析 · 数学 2019-02-14 Alessandro Audrito , Juan Luis Vázquez

We show that propagation speeds in invasion processes modeled by reaction-diffusion systems are determined by marginal spectral stability conditions, as predicted by the marginal stability conjecture. This conjecture was recently settled in…

偏微分方程分析 · 数学 2023-10-24 Montie Avery
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