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相关论文: Generalized Hopf Bifurcation in a Cancer Model wit…

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We consider two minimal mathematical models for cancer dynamics and self-adaptation. We aim to capture the interplay between the rapid progression of cancer growth and the possibility to leverage and enhance self-adaptive defense mechanisms…

适应与自组织系统 · 物理学 2025-03-27 Christian Kuehn

This paper focuses on Hopf bifurcation control in a dual model of Internet congestion control algorithms which is modeled as a delay differential equation (DDE). By choosing communication delay as a bifurcation parameter, it has been…

网络与互联网体系结构 · 计算机科学 2007-12-24 Dawei Ding , Jie Zhu , Xiaoshu Luo , Yuliang Liu

Nonautonomous bifurcation theory is a growing branch of mathematics, for the insight it provides into radical changes in the global dynamics of realistic models for many real-world phenomena, i.e., into the occurrence of critical…

动力系统 · 数学 2025-01-08 Cinzia Elia , Roberta Fabbri , Carmen Núñez

Understanding the cross-species behavior of cancer is important for uncovering fundamental mechanisms of carcinogenesis, and for translating results of model systems between species. One of the most famous interspecific considerations of…

其他定量生物学 · 定量生物学 2020-11-24 Christopher P. Kempes , Geoffrey B. West , John W. Pepper

In this article we provide homotopy solutions of a cancer nonlinear model describing the dynamics of tumor cells in interaction with healthy and effector immune cells. We apply a semi-analytic technique for solving strongly nonlinear…

In this work, we investigate the dynamical properties of a reaction-diffusion system arising from tumor-therapy modelling that features both nonlinear interactions and nonlocal delay. By applying the Lyapunov-Schmidt reduction, we establish…

动力系统 · 数学 2025-12-17 Dandan Hu , Yuan Yuan

Cell competition is recognized to be instrumental to the dynamics and structure of the tumor-host interface in invasive cancers. In mild competition scenarios, the healthy tissue and cancer cells can coexist. When the competition is…

种群与进化 · 定量生物学 2022-04-19 Heyrim Cho , Doron Levy

For many physical systems the transition from a stationary solution to sustained small amplitude oscillations corresponds to a Hopf bifurcation. For systems involving impacts, thresholds, switches, or other abrupt events, however, this…

动力系统 · 数学 2019-05-07 David J. W. Simpson

We investigate a diffusive, stage-structured epidemic model with the maturation delay and freely-moving delay. Choosing delays and diffusive rates as bifurcation parameters, the only possible way to destabilize the endemic equilibrium is…

动力系统 · 数学 2018-05-25 Yanfei Du , Ben Niu , Junjie Wei

In the natural world, there are many insect species whose individual members have a life history that takes them through two stages, immature and mature. Moreover, the rates of survival, development, and reproduction almost always depend on…

动力系统 · 数学 2013-02-26 Kunwer Singh Jatav , Joydip Dhar

Hopf bifurcation in networks of coupled ODEs creates periodic states in which the relative phases of nodes are well defined near bifurcation. When the network is a fully inhomogeneous nearest-neighbour coupled unidirectional ring, and node…

动力系统 · 数学 2024-04-15 Ian Stewart

We analyse a modified Holling-Tanner predator-prey model where the predation functional response is of Holling type II and we incorporate a strong Allee effect associated with the prey species production. The analysis complements results of…

In this work we prove occurrence of a super-critical Hopf bifurcation in a model of white blood cell formation structured by three maturation stages. We provide an explicit analytical expression for the bifurcation point depending on model…

动力系统 · 数学 2019-10-24 Franziska Knauer , Thomas Stiehl , Anna Marciniak-Czochra

On base of Hamiltonian formalism, we show that Hopf bifurcation arrives, in the course of the system evolution, at creation of revolving region of the phase plane being bounded by limit cycle. A revolving phase plane with a set of limit…

统计力学 · 物理学 2007-05-23 A. I. Olemskoi , I. A. Shuda

This paper investigates the dynamic behavior of a simplified single reed instrument model subject to a stochastic forcing of white noise type when one of its bifurcation parameters (the dimensionless blowing pressure) increases linearly…

混沌动力学 · 物理学 2026-02-02 Baptiste Bergeot , Christophe Vergez

A phenomenon that strongly influences the demography of small introduced populations and thereby potentially their genetic diversity is the Allee effect, a reduction in population growth rates at small population sizes. We take a stochastic…

种群与进化 · 定量生物学 2013-11-25 Meike J. Wittmann , Wilfried Gabriel , Dirk Metzler

The Allee effect is an important phenomenon in population biology characterized by positive density dependence, that is a positive correlation between population density and individual fitness. However, the effect is not well studied in…

偏微分方程分析 · 数学 2015-10-20 Rana D. Parshad , Emmanuel Quansah , Kelly Black , Nitu Kumari , Ranjit K. Upadhyay , S. K. Tiwari

Although the immune response is often regarded as acting to suppress tumor growth, it is now clear that it can be both stimulatory and inhibitory. The interplay between these competing influences has complex implications for tumor…

细胞行为 · 定量生物学 2013-05-17 Kathleen P. Wilkie , Philip Hahnfeldt

We consider a Gatenby--Gawlinski-type model of invasive tumors in the presence of an Allee effect. We describe the construction of bistable one-dimensional traveling fronts using singular perturbation techniques in different parameter…

偏微分方程分析 · 数学 2024-08-30 Paul Carter , Arjen Doelman , Peter van Heijster , Daniel Levy , Philip Maini , Erin Okey , Paige Yeung

We performed a thorough sensitivity analysis of the herd immunity threshold for discrete-time SIR compartmental models with a static network structure. We find unexpectedly that these models violate classical intuition which holds that the…

种群与进化 · 定量生物学 2023-02-27 Sinan A. Ozbay , Bjarke F. Nielsen , Maximilian M. Nguyen