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This paper introduces a spatiotemporal SEIQR epidemic model governed by a system of reaction-diffusion partial differential equations that incorporates optimal control strategies. The model captures the transmission dynamics of an…

动力系统 · 数学 2025-07-29 Achraf Zinihi , Matthias Ehrhardt , Moulay Rchid Sidi Ammi

We investigate the celebrated mathematical SICA model but using fractional differential equations in order to better describe the dynamics of HIV-AIDS infection. The infection process is modelled by a general functional response and the…

This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…

最优化与控制 · 数学 2023-04-24 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

An adequate near-optimal control problem for a stochastic SICA (Susceptible-Infected-Chronic-AIDS) compartmental epidemic model for HIV transmission with imprecise parameters is formulated and investigated. We prove some estimates for the…

最优化与控制 · 数学 2022-12-06 Houssine Zine , Delfim F. M. Torres

This paper is about numerical control of HIV propagation. The contribution of the paper is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the…

系统与控制 · 计算机科学 2023-05-30 Dmitry Gromov , Ingo Bulla , Ethan O. Romero-Severson , Oana Silvia Serea

In this paper, we consider an optimal distributed control problem for a reaction-diffusion-based SIR epidemic model with human behavioral effects. We develop a model wherein non-pharmaceutical intervention methods are implemented, but a…

偏微分方程分析 · 数学 2025-02-11 Marcelo Bongarti , Christian Parkinson , Weinan Wang

In this article, we consider an HIV/AIDS epidemic model with four classes of individuals. We have discussed about basic properties of the system and found the basic reproduction number $R_0$ of the system. The stability analysis of the…

动力系统 · 数学 2023-04-18 Nouar Chorfi , Salem Abdelmalek , Samir Bendoukha

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

种群与进化 · 定量生物学 2020-05-04 Andrew Lesniewski

We revisit the SICA (Susceptible-Infectious-Chronic-AIDS) mathematical model for transmission dynamics of the human immunodeficiency virus (HIV) with varying population size in a homogeneously mixing population. We consider SICA models…

种群与进化 · 定量生物学 2020-08-10 Cristiana J. Silva , Delfim F. M. Torres

We propose a stochastic SICA epidemic model for HIV transmission, described by stochastic ordinary differential equations, and discuss its perturbation by environmental white noise. Existence and uniqueness of the global positive solution…

种群与进化 · 定量生物学 2018-05-30 Jasmina Djordjevic , Cristiana J. Silva , Delfim F. M. Torres

We approach the development of models and control strategies of susceptible-infected-susceptible (SIS) epidemic processes from the perspective of marked temporal point processes and stochastic optimal control of stochastic differential…

最优化与控制 · 数学 2018-12-04 Lars Lorch , Abir De , Samir Bhatt , William Trouleau , Utkarsh Upadhyay , Manuel Gomez-Rodriguez

In this paper, we study a novel control method for a generalized SIS epidemic process. In particular, we use predictive control to design optimal protective resource distribution strategies which balance the need to eliminate the epidemic…

最优化与控制 · 数学 2018-08-17 Nicholas J. Watkins , George J. Pappas

In this paper, we explore the solvability and the optimal control problem for a compartmental model based on reaction-diffusion partial differential equations describing a transmissible disease. The nonlinear model takes into account the…

最优化与控制 · 数学 2023-08-25 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi

In this paper, we formulate cyber risk management and mitigation as a stochastic optimal control problem under a stochastic Susceptible-Infected-Susceptible (SIS) epidemic model. To capture the dynamics and interplay of management and…

最优化与控制 · 数学 2026-01-29 Shize Na , Zhuo Jin , Ran Xu , Hailiang Yang

Controlling an epidemiological model is often performed using optimal control theory techniques for which the solution depends on the equations of the control system, objective functional and possible state and/or control constraints. In…

最优化与控制 · 数学 2021-11-25 Loïc Michel , Cristiana J. Silva , Delfim F. M. Torres

We consider the problem of controlling an SIR-model epidemic by temporarily reducing the rate of contact within a population. The control takes the form of a multiplicative reduction in the contact rate of infectious individuals. The…

最优化与控制 · 数学 2021-06-29 David I. Ketcheson

The main aim of this study is to analyze a fractional parabolic SIR epidemic model of a reaction-diffusion, by using the nonlocal Caputo fractional time-fractional derivative and employing the $p$-Laplacian operator. The immunity is imposed…

最优化与控制 · 数学 2025-04-25 Achraf Zinihi , Moulay Rchid Sidi Ammi , Delfim F. M. Torres

We review the optimal control of systems modeling the dynamics of tuberculosis. Time dependent control functions are introduced in the mathematical models, representing strategies for the improvement of the treatment and cure of active…

最优化与控制 · 数学 2015-08-18 Cristiana J. Silva , Delfim F. M. Torres

Reliable estimation of spatio-temporal trends in population-level HIV incidence is becoming an increasingly critical component of HIV prevention policy-making. However, direct measurement is nearly impossible. Current, widely used models…

应用统计 · 统计学 2019-12-04 Timothy M Wolock , Seth R Flaxman , Jeffrey W Eaton

This work focuses on optimal controls of a class of stochastic SIS epidemic models under regime switching. By assuming that a decision maker can either influence the infectivity period or isolate infected individuals, our aim is to minimize…

最优化与控制 · 数学 2021-01-12 Ky Tran , George Yin
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