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An algorithm for estimating quasi-stationary distribution of finite state space Markov chains has been proven in a previous paper. Now this paper proves a similar algorithm that works for general state space Markov chains under very general…

概率论 · 数学 2015-03-04 Jose H. Blanchet , Peter Glynn , Shuheng Zheng

Computing the stationary distributions of a continuous-time Markov chain (CTMC) involves solving a set of linear equations. In most cases of interest, the number of equations is infinite or too large, and the equations cannot be solved…

概率论 · 数学 2020-08-25 Juan Kuntz , Philipp Thomas , Guy-Bart Stan , Mauricio Barahona

We derive the nonequilibrium conductance matrix for open stationary Chemical Reaction Networks (CRNs) described by a deterministic mass action kinetic equation. As an illustration, we determine the nonequilibrium conductance matrix of a CRN…

统计力学 · 物理学 2025-06-27 Paul Raux , Christophe Goupil , Gatien Verley

Chemical reaction networks (CRNs) exhibit complex dynamics governed by their underlying network structure. In this paper, we propose a novel approach to study the dynamics of CRNs by representing them on species graphs (S-graphs). By…

分子网络 · 定量生物学 2024-04-24 Keisuke Sugie , Dimitri Loutchko , Tetsuya J. Kobayashi

Chemical reaction networks (CRNs) are foundational models for describing complex biochemical processes. We study noncompetitive CRNs, a class of networks whose static states are rate-independent, and that can implement ReLU neural networks.…

分子网络 · 定量生物学 2025-12-22 Louis Faul , Xavier Richard , Mary Betrisey , Christian Mazza

It is well known that stochastically modeled reaction networks that are complex balanced admit a stationary distribution that is a product of Poisson distributions. In this paper, we consider the following related question: supposing that…

概率论 · 数学 2019-11-19 David F. Anderson , David Schnoerr , Chaojie Yuan

Chemical reaction network theory is a field of applied mathematics concerned with modeling chemical systems, and can be used in other contexts such as in systems biology to study cellular signaling pathways or epidemiology to study the…

The graph-related symmetries of a reaction network give rise to certain special equilibria (such as complex balanced equilibria) in deterministic models of dynamics of the reaction network. Correspondingly, in the stochastic setting, when…

概率论 · 数学 2018-05-21 Daniele Cappelletti , Badal Joshi

The asymptotic properties of some Markov processes associated to stochastic chemical reaction networks (CRNs) driven by the kinetics of the law of mass action are analyzed. The scaling regime introduced in the paper assumes that the norm of…

概率论 · 数学 2025-12-18 Lucie Laurence , Philippe Robert

Living systems operate out of equilibrium, continuously consuming energy to sustain organised, functional states. Their emergent behaviour usually relies on a set of interconnected chemical reaction networks (CRNs) driven by external fluxes…

统计力学 · 物理学 2026-02-03 Shiling Liang , Paolo De Los Rios , Daniel Maria Busiello

Stochastic reaction networks with mass-action kinetics provide a useful framework for understanding processes -- biochemical and otherwise -- in homogeneous environments. However, cellular reactions are often compartmentalized, either at…

概率论 · 数学 2026-05-01 David F. Anderson , Aidan S. Howells , Diego Rojas La Luz

The goal of this paper is to gather and develop some necessary and sufficient criteria for injectivity and multistationarity in vector fields associated with a chemical reaction network under a variety of more or less general assumptions on…

动力系统 · 数学 2016-10-28 Murad Banaji , Casian Pantea

The paper deals with non-linear Poisson neuron network models with bounded memory dynamics, that can include both Hebbian learning mechanisms and refractory periods. The state of a network is described by the times elapsed since its neurons…

概率论 · 数学 2012-06-21 Konstantin Borovkov , Geoffrey Decrouez , Matthieu Gilson

Well-mixed chemical reaction networks (CRNs) contain many distinct chemical species with copy numbers that fluctuate in correlated ways. While those correlations are typically monitored via Monte Carlo sampling of stochastic trajectories,…

统计力学 · 物理学 2026-01-14 John P. Zima , Schuyler B. Nicholson , Todd R. Gingrich

Coupled chemical interactions in a well-mixed solution are commonly formalized as chemical reaction networks (CRNs). However, despite the widespread use of CRNs in the natural sciences, the range of computational behaviors exhibited by CRNs…

新兴技术 · 计算机科学 2023-04-11 Ho-Lin Chen , David Doty , Wyatt Reeves , David Soloveichik

Motivation: A Chemical Reaction Network (CRN) is a set of chemical reactions, which can be very complex and difficult to analyze. Indeed, dynamical properties of CRNs can be described by a set of non-linear differential equations that…

计算工程、金融与科学 · 计算机科学 2021-07-02 Lucia Nasti , Roberta Gori , Paolo Milazzo , Federico Poloni

Stochastic reaction networks are mathematical models with a wide range of applications in biochemistry, ecology, and epidemiology, and are often complex to analyze. Except for some special cases, it is generally difficult to predict how the…

概率论 · 数学 2026-04-02 Daniele Cappelletti , Giulio Cuniberti , Paola Siri

Stochastic reaction network models arise in intracellular chemical reactions, epidemiological models and other population process models, and are a class of continuous time Markov chains which have the nonnegative integer lattice as state…

数值分析 · 数学 2024-07-26 Muruhan Rathinam , Mingkai Yu

Biological systems exhibit processes on a wide range of time and length scales. This work demonstrates that models, wherein the interaction between system constituents is captured by algebraic operations, inherently allow for successive…

分子网络 · 定量生物学 2019-08-16 Dimitri Loutchko

Tensor structured Markov chains are part of stochastic models of many practical applications, e.g., in the description of complex production or telephone networks. The most interesting question in Markov chain models is the determination of…

数值分析 · 数学 2015-05-08 Matthias Bolten , Karsten Kahl , Sonja Sokolović