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Deterministic reaction networks (RNs) are tools to model diverse biological phenomena characterized by particle systems, when there are abundant number of particles. Examples include but are not limited to biochemistry, molecular biology,…

分子网络 · 定量生物学 2021-07-22 Carsten Wiuf , Chuang Xu

Reaction networks (RNs) comprise a set $X$ of species and a set $\mathscr{R}$ of reactions $Y\to Y'$, each converting a multiset of educts $Y\subseteq X$ into a multiset $Y'\subseteq X$ of products. RNs are equivalent to directed…

分子网络 · 定量生物学 2022-01-06 Stefan Müller , Christoph Flamm , Peter F. Stadler

Which reaction networks, when taken with mass-action kinetics, have the capacity for multiple steady states? There is no complete answer to this question, but over the last 40 years various criteria have been developed that can answer this…

动力系统 · 数学 2015-08-21 Badal Joshi , Anne Shiu

The paper is devoted to studies of perturbed Markov chains commonly used for description of information networks. In such models, the matrix of transition probabilities for the corresponding Markov chain is usually regularised by adding a…

We discuss recent developments in the formulation of a Statistical Mechanics approach to non thermal systems, such as granular media. We review a few important numerical results on the assessment of Edwards' theory and, in particular, we…

凝聚态物理 · 物理学 2009-11-10 Antonio Coniglio , Annalisa Fierro , Mario Nicodemi

This work reviews deterministic and diffusion approximations of the stochastic chemical reaction networks and explains their applications. We discuss the added value the diffusion approximation provides for systems with different phenomena,…

We analyze the behavior of closed product-form queueing networks when the number of customers grows to infinity and remains proportionate on each route (or class). First, we focus on the stationary behavior and prove the conjecture that the…

概率论 · 数学 2014-04-11 Jonatha Anselmi , Bernardo D'Auria , Neil Walton

We introduce a novel training principle for probabilistic models that is an alternative to maximum likelihood. The proposed Generative Stochastic Networks (GSN) framework is based on learning the transition operator of a Markov chain whose…

For general, almost surely absorbed Markov processes, we obtain necessary and sufficient conditions for exponential convergence to a unique quasi-stationary distribution in the total variation norm. These conditions also ensure the…

概率论 · 数学 2014-12-25 Nicolas Champagnat , Denis Villemonais

We consider periodic Markov chains with absorption. Applying to iterates of this periodic Markov chain criteria for the exponential convergence of conditional distributions of aperiodic absorbed Markov chains, we obtain exponential…

概率论 · 数学 2022-11-08 Nicolas Champagnat , Denis Villemonais

We derive and analyze new diffusion approximations of stationary distributions of Markov chains that are based on second- and higher-order terms in the expansion of the Markov chain generator. Our approximations achieve a higher degree of…

概率论 · 数学 2022-07-12 Anton Braverman , J. G. Dai , Xiao Fang

Physically motivated stochastic dynamics are often used to sample from high-dimensional distributions. However such dynamics often get stuck in specific regions of their state space and mix very slowly to the desired stationary state. This…

机器学习 · 统计学 2025-05-13 Abhijith Jayakumar , Andrey Y. Lokhov , Sidhant Misra , Marc Vuffray

The problem of time-series clustering is considered in the case where each data-point is a sample generated by a piecewise stationary ergodic process. Stationary processes are perhaps the most general class of processes considered in…

机器学习 · 统计学 2019-06-27 Azadeh Khaleghi , Daniil Ryabko

We define a de Bruijn process with parameters n and L as a certain continuous-time Markov chain on the de Bruijn graph with words of length L over an n-letter alphabet as vertices. We determine explicitly its steady state distribution and…

概率论 · 数学 2013-10-09 Arvind Ayyer , Volker Strehl

We model non-stationary volume-price distributions with a log-normal distribution and collect the time series of its two parameters. The time series of the two parameters are shown to be stationary and Markov-like and consequently can be…

统计金融 · 定量金融 2017-05-04 Joana Estevens , Paulo Rocha , Joao Boto , Pedro Lind

We provide a functional view of distributional robustness motivated by robust statistics and functional analysis. This results in two practical computational approaches for approximate distributionally robust nonlinear optimization based on…

系统与控制 · 电气工程与系统科学 2021-10-27 Yassine Nemmour , Bernhard Schölkopf , Jia-Jie Zhu

We present a data-driven verification approach that determines whether or not a given chemical reaction network (CRN) satisfies a given property, expressed as a formula in a modal logic. Our approach consists of three phases, integrating…

计算工程、金融与科学 · 计算机科学 2020-04-24 Gareth W. Molyneux , Viraj B. Wijesuriya , Alessandro Abate

Chemical Reaction Networks (CRNs) provide a useful abstraction of molecular interaction networks in which molecular structures as well as mass conservation principles are abstracted away to focus on the main dynamical properties of the…

分子网络 · 定量生物学 2020-07-31 Elisabeth Degrand , François Fages , Sylvain Soliman

Many biochemical and industrial applications involve complicated networks of simultaneously occurring chemical reactions. Under the assumption of mass action kinetics, the dynamics of these chemical reaction networks are governed by systems…

动力系统 · 数学 2014-07-15 Matthew D. Johnston

We present a novel method for identifying a biochemical reaction network based on multiple sets of estimated reaction rates in the corresponding reaction rate equations arriving from various (possibly different) experiments. The current…

应用统计 · 统计学 2008-10-06 Gheorghe Craciun , Casian Pantea , Grzegorz A. Rempala
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