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Continuous time Markov chains are commonly used as models for the stochastic behavior of chemical reaction networks. More precisely, these Stochastic Chemical Reaction Networks (SCRNs) are frequently used to gain a mechanistic understanding…

While convolutional neural networks (CNNs) trained by back-propagation have seen unprecedented success at semantic segmentation tasks, they are known to struggle on out-of-distribution data. Markov random fields (MRFs) on the other hand,…

计算机视觉与模式识别 · 计算机科学 2021-04-13 Mikael Brudfors , Yaël Balbastre , John Ashburner , Geraint Rees , Parashkev Nachev , Sébastien Ourselin , M. Jorge Cardoso

Certain chemical reaction networks (CRNs) when modeled as a deterministic dynamical system taken with mass-action kinetics have the property of reaction network detailed balance (RNDB) which is achieved by imposing network-related…

概率论 · 数学 2014-12-30 Badal Joshi

Cycles, which can be found in many different kinds of networks, make the problems more intractable, especially when dealing with dynamical processes on networks. On the contrary, tree networks in which no cycle exists, are simplifications…

物理与社会 · 物理学 2021-04-07 Wenjun Zhang , Wei Li , Weibing Deng

Modeling joint probability distributions over sequences has been studied from many perspectives. The physics community developed matrix product states, a tensor-train decomposition for probabilistic modeling, motivated by the need to…

机器学习 · 计算机科学 2020-10-22 Siddarth Srinivasan , Sandesh Adhikary , Jacob Miller , Guillaume Rabusseau , Byron Boots

A Markovian single-server queue is studied in an interactive random environment. The arrival and service rates of the queue depend on the environment, while the transition dynamics of the random environment depends on the queue length. We…

概率论 · 数学 2020-01-10 Yana Belopolskaya , Guodong Pang , Andrey Sarantsev , Yurii Suhov

Markov chains for probability distributions related to matrix product states and 1D Hamiltonians are introduced. With appropriate 'inverse temperature' schedules, these chains can be combined into a random approximation scheme for ground…

强关联电子 · 物理学 2014-05-14 S. Iblisdir

We address a fundamental question: under which conditions do the dynamics and thermodynamics of open chemical reaction networks (CRNs), grounded on the notion of idealized chemostats that exchange selected species, emerge from underlying…

统计力学 · 物理学 2026-04-17 Benedikt Remlein , Massimiliano Esposito , Francesco Avanzini

The catalytic reaction system (CRS) formalism by Hordijk and Steel is a versatile method to model autocatalytic biochemical reaction networks. It is particularly suited, and has been widely used, to study self-sustainment and…

分子网络 · 定量生物学 2023-08-16 Dimitri Loutchko

Recent research into analog computing has introduced new notions of computing real numbers. Huang, Klinge, Lathrop, Li, and Lutz defined a notion of computing real numbers in real-time with chemical reaction networks (CRNs), introducing the…

新兴技术 · 计算机科学 2021-09-08 Willem Fletcher , Titus H. Klinge , James I. Lathrop , Dawn A. Nye , Matthew Rayman

Much recent research activity has been devoted to empirical study and theoretical models of complex networks (random graphs) with three qualitative features: power-law degree distribution, local clustering of edges, and small diameter. We…

无序系统与神经网络 · 物理学 2017-08-23 David J. Aldous

The study of probabilistic models for the analysis of complex networks represents a flourishing research field. Among the former, Exponential Random Graphs (ERGs) have gained increasing attention over the years. So far, only linear ERGs…

物理与社会 · 物理学 2026-02-10 Mattia Marzi , Francesca Giuffrida , Diego Garlaschelli , Tiziano Squartini

We propose a Markov chain simulation method to generate simple connected random graphs with a specified degree sequence and level of clustering. The networks generated by our algorithm are random in all other respects and can thus serve as…

离散数学 · 计算机科学 2010-02-09 Shweta Bansal , Shashank Khandelwal , Lauren Ancel Meyers

The integration of Graph Neural Networks (GNNs) and Neural Ordinary and Partial Differential Equations has been extensively studied in recent years. GNN architectures powered by neural differential equations allow us to reason about their…

机器学习 · 计算机科学 2024-06-18 Moshe Eliasof , Eldad Haber , Eran Treister

From the perspective of probability, the stability of growing network is studied in the present paper. Using the DMS model as an example, we establish a relation between the growing network and Markov process. Based on the concept and…

数学物理 · 物理学 2008-06-02 Zhenting Hou , Jinying Tong , Dinghua Shi

Recurrent neural networks (RNNs) are widely used throughout neuroscience as models of local neural activity. Many properties of single RNNs are well characterized theoretically, but experimental neuroscience has moved in the direction of…

机器学习 · 计算机科学 2023-01-31 Leo Kozachkov , Michaela Ennis , Jean-Jacques Slotine

We consider a family of measure preserving transformations, which act on a common probability space and are chosen at random by a stationary ergodic Markov chain. This setting defines an instance of a random dynamical system (RDS), which…

动力系统 · 数学 2024-02-27 Pablo Lummerzheim , Felix Pogorzelski , Elias Zimmermann

The spatially distributed reaction networks are indispensable for the understanding of many important phenomena concerning the development of organisms, coordinated cell behavior, and pattern formation. The purpose of this brief discussion…

最优化与控制 · 数学 2013-05-15 Marko Seslija , Jacquelien M. A. Scherpen , Arjan van der Schaft

A reaction system exhibits "absolute concentration robustness" (ACR) in some species if the positive steady-state value of that species does not depend on initial conditions. Mathematically, this means that the positive part of the variety…

动力系统 · 数学 2022-06-08 Nicolette Meshkat , Anne Shiu , Angélica Torres

We consider a continuous-time Markov chain (CTMC) whose state space is partitioned into aggregates, and each aggregate is assigned a probability measure. A sufficient condition for defining a CTMC over the aggregates is presented as a…

离散数学 · 计算机科学 2013-03-21 Arnab Ganguly , Tatjana Petrov , Heinz Koeppl