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In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

最优化与控制 · 数学 2024-11-08 Nelson L. Santos Junior , João A. M. Gondim

We study an optimal control problem for a non-autonomous SEIRS model with incidence given by a general function of the infective, the susceptible and the total population, and with vaccination and treatment as control variables. We prove…

最优化与控制 · 数学 2018-06-13 Joaquim P. Mateus , Paulo Rebelo , Silvério Rosa , César M. Silva , Delfim F. M. Torres

We develop a mathematical model for transferring the vaccine BNT162b2 based on the heat diffusion equation. Then, we apply optimal control theory to the proposed generalized SEIR model. We introduce vaccination for the susceptible…

最优化与控制 · 数学 2022-04-22 Mohamed Abdelaziz Zaitri , Mohand Ouamer Bibi , Delfim F. M. Torres

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

最优化与控制 · 数学 2016-12-28 Olga Klimenkova

This work will study an optimal control problem describing the two-strain SEIR epidemic model. The studied model is in the form of six nonlinear differential equations illustrating the dynamics of the susceptibles and the exposed, the…

种群与进化 · 定量生物学 2024-04-29 Karam Allali , Mouhamadou A. M. T. Balde , Babacar M. Ndiaye

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

最优化与控制 · 数学 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

In this paper we introduce an approach to the management of infectious disease diffusion through the formulation of a controlled compartmental SVIR (Susceptible-Vaccinated-Infected-Recovered) model. We consider a cost functional…

最优化与控制 · 数学 2023-11-28 Alessandro Ramponiand M. Elisabetta Tessitore

The paper considers the problems of optimal vaccination control in the classical SIR model under constraints on the resource capabilities of the insurance medical system, in particular under constraints on the possible absolute rate of…

最优化与控制 · 数学 2025-11-24 Bogdan Norkin , Vladimir Norkin

This study aims to determine an optimal control strategy for vaccine scheduling in COVID-19 pandemic treatment by converting widely acknowledged infectious disease model named SEIR into an optimal control problem. The problem is augmented…

种群与进化 · 定量生物学 2020-08-26 Syed Irfan Ali Meerza , Seyed M. Karimi , Bert B. Little , Jacek M. Zurada , Tamer Inanc

This paper presents a vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population amounts as a refrain for…

动力系统 · 数学 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

This paper presents several simple linear vaccination-based control strategies for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population…

动力系统 · 数学 2011-03-28 M. De la Sen , S. Alonso-Quesada

In this study, we present an epidemic-controlled SIRD model with two types of control strategies: mask wear and screening. The aim of this study is to minimize the number of deceased keeping a minimal cost of mask advertising and screening.…

种群与进化 · 定量生物学 2021-09-06 Amira Bouhali , Walid Ben Aribi , Slimane Ben Miled , Amira Kebir

We apply optimal control theory to a generalized SEIR-type model. The proposed system has three controls, representing social distancing, preventive means, and treatment measures to combat the spread of the COVID-19 pandemic. We analyze…

最优化与控制 · 数学 2021-12-10 Mohamed Abdelaziz Zaitri , Mohand Ouamer Bibi , Delfim F. M. Torres

This article considers the optimal control of the SIR model with both transmission and treatment uncertainty. It follows the model presented in Gatto and Schellhorn (2021). We make four significant improvements on the latter paper. First,…

最优化与控制 · 数学 2021-05-20 Yujia Ding , Henry Schellhorn

This paper deals with an SIR model with saturated incidence rate affected by inhibitory effect and saturated treatment function. Two control functions have been used, one for vaccinating the susceptible population and other for the…

动力系统 · 数学 2018-07-17 Jayanta Kumar Ghosh , Uttam Ghosh , M. H. A. Biswas , Susmita Sarkar

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

最优化与控制 · 数学 2020-12-22 Hailiang Liu , Xuping Tian

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

种群与进化 · 定量生物学 2021-08-17 Evangelos F. Magirou

During decades, mathematical models have been used to predict the behavior of physical and biologic systems, and to define strategies aiming the minimization of the effects regarding different types of diseases. In the present days, the…

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

最优化与控制 · 数学 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

This paper introduces a spatiotemporal SEIQR epidemic model governed by a system of reaction-diffusion partial differential equations that incorporates optimal control strategies. The model captures the transmission dynamics of an…

动力系统 · 数学 2025-07-29 Achraf Zinihi , Matthias Ehrhardt , Moulay Rchid Sidi Ammi
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