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We investigate the dynamics of the hepatitis B virus by integrating variable-order calculus and discrete analysis. Specifically, we utilize the Caputo variable-order difference operator in this study. To establish the existence and…

种群与进化 · 定量生物学 2024-05-27 Meriem Boukhobza , Amar Debbouche , Lingeshwaran Shangerganesh , Delfim F. M. Torres

This study presents an improved mathematical model for Hepatitis B Virus (HBV) transmission dynamics by investigating autonomous and nonautonomous cases. The novel model incorporates the effects of medical treatment, allowing for a more…

动力系统 · 数学 2025-05-15 Abdallah Alsammani

Analysis of the cell population generally provides average information about viral infection in a host whereas the intracellular model captures the individual cellular responses. The primary goal of this study is to comprehensively analyze…

动力系统 · 数学 2025-05-20 Rupchand Sutradhar , D C Dalal

Long-term memory is a feature observed in systems ranging from neural networks to epidemiological models. The memory in such systems is usually modeled by the time delay. Furthermore, the nonlocal operators, such as the "fractional order…

动力系统 · 数学 2023-05-12 Divya D. Joshi , Sachin Bhalekar , Prashant M. Gade

This study develops and analyzes a stochastic differential equation (SDE) model for the dynamics of hepatitis B virus (HBV) infection. While deterministic frameworks have yielded important insights into viral behavior, they cannot…

动力系统 · 数学 2025-10-03 Abdallah Alsammani

Fractional differential equations model processes with memory effects, providing a realistic perspective on complex systems. We examine time-delayed differential equations, discussing first-order and fractional Caputo time-delayed…

广义相对论与量子宇宙学 · 物理学 2025-05-08 Bayron Micolta-Riascos , Byron Droguett , Gisel Mattar Marriaga , Genly Leon , Andronikos Paliathanasis , Luis del Campo , Yoelsy Leyva

In this research, we have derived a mathematical model for within human dynamics of COVID-19 infection using delay differential equations. The new model considers a 'latent period' and 'the time for immune response' as delay parameters,…

种群与进化 · 定量生物学 2025-01-14 Amar N. Chatterjee , Teklebirhan Abraha , Fahad Al Basir , Delfim F. M. Torres

This paper is devoted to the investigation of the nonnegative solutions and the stability and asymptotic properties of the solutions of fractional differential dynamic systems involving delayed dynamics with point delays. The obtained…

动力系统 · 数学 2010-09-23 Manuel De la Sen

In this paper we present a delay induced model for hepatitis C virus incorporating the healthy and infected hepatocytes as well as infectious and noninfectious virions. The model is mathematically analyzed and characterized, both for the…

动力系统 · 数学 2014-03-11 Sandip Banerjee , Ram Keval , Sunita Gakkhar

Hepatitis B virus infection is a deadly liver disease. A part of newly produced HBV DNA-containing capsids are reused as a core particle in HBV replication. It is investigated that the recycling of HBV capsids greatly affects the…

动力系统 · 数学 2023-09-28 Rupchand Sutradhar , D C Dalal

Chronic infection with hepatitis B virus (HBV) can lead to formation of abnormal nodular structures within the liver. To address how changes in liver anatomy affect overall virus-host dynamics, we developed within-host ordinary differential…

其他定量生物学 · 定量生物学 2025-08-01 Keoni Castellano , Omar Saucedo , Stanca M. Ciupe

A virus dynamics model with intracellular state-dependent delay and nonlinear infection rate of Beddington-DeAngelis functional response is studied. The technique of Lyapunov functionals is used to analyze stability of an interior infection…

动力系统 · 数学 2017-06-29 Alexander Rezounenko

We propose a Caputo type fractional-order mathematical model for the transmission dynamics of tuberculosis (TB). Uniform asymptotic stability of the unique endemic equilibrium of the fractional-order TB model is proved, for any $\alpha \in…

最优化与控制 · 数学 2018-04-10 Weronika Wojtak , Cristiana J. Silva , Delfim F. M. Torres

A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady…

种群与进化 · 定量生物学 2018-05-16 F. Fatehi Chenar , Y. N. Kyrychko , K. B. Blyuss

Fractional derivative and delay are important tools in modeling memory properties in the natural system. This work deals with the stability analysis of a fractional order delay differential equation \begin{equation*} D^\alpha x(t)=\delta…

动力系统 · 数学 2022-08-29 Sachin Bhalekar , Deepa Gupta

In this paper, a mathematical analysis of the global dynamics of a partial differential equation viral infection cellular model is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both…

偏微分方程分析 · 数学 2021-11-08 Alexis Nangue , Bruno Nde Tchiffo

In recent years, discrete fractional epidemic models with reaction-diffusion have become increasingly popular in the literature, not only for its necessity of numerical simulation, but also for its defined physical processes. In this paper,…

数值分析 · 数学 2022-08-16 Lu Zhenzhen , Yu Yongguang , Xu Weiyi , Ren Guojian , Meng Xiangyun

The logistic growth model is a classical framework for describing constrained growth phenomena, widely applied in areas such as population dynamics, epidemiology, and resource management. This study presents a generalized extension using…

系统与控制 · 电气工程与系统科学 2025-10-20 M. O. Aibinu , A. Shoukat , F. M. Mahomed

This paper investigates the global stability and the global asymptotic stability independent of the sizes of the delays of linear time-varying Caputo fractional dynamic systems of real fractional order possessing internal point delays. The…

动力系统 · 数学 2010-10-18 M. De La Sen

Epidemic models play a crucial role in population dynamics, offering valuable insights into disease transmission while aiding in epidemic prediction and control. In this paper, we analyze the mathematical model of the time-fractional Zika…

动力系统 · 数学 2026-02-24 Gaurav Saini , Bappa Ghosh , Sunita Chand
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