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Understanding age-group dynamics of infectious diseases is a fundamental issue for both scientific study and policymaking. Age-structure epidemic models were developed in order to study and improve our understanding of these dynamics. By…

种群与进化 · 定量生物学 2019-11-22 Rami Yaari , Amit Huppert , Itai Dattner

For a heterogeneous host population, the basic reproduction number of an infectious disease, $\cR_0$, is defined as the spectral radius of the next generation operator (NGO). The threshold properties of the basic reproduction number are…

种群与进化 · 定量生物学 2025-04-29 Horst R Thieme

We introduce a model for the evolution of sexually transmitted diseases, in which the social behavior is incorporated as a determinant factor for the further propagation of the infection. The system may be regarded as a society of agents…

统计力学 · 物理学 2009-11-07 Sebatian Goncalves , Marcelo Kuperman

The Mekong Delta Region of Vietnam faces increasing dengue risks driven by urbanization, globalization, and climate change. This study introduces a probabilistic forecasting model for predicting dengue incidence and outbreaks with one to…

We analyse an epidemiological model of competing strains of pathogens and hence differences in transmission for first versus secondary infection due to interaction of the strains with previously aquired immunities, as has been described for…

种群与进化 · 定量生物学 2008-06-30 Maira Aguiar , Nico Stollenwerk , Bob W. Kooi

Dengue, a mosquito-borne disease, continues to pose a persistent public health challenge in urban areas, particularly in tropical regions such as Singapore. Effective and affordable control requires anticipating where transmission risks are…

人工智能 · 计算机科学 2026-01-26 Liping Huang , Gaoxi Xiao , Stefan Ma , Hechang Chen , Shisong Tang , Flora Salim

Despite being similar in structure, functioning, and size viral pathogens enjoy very different mostly well-defined ways of life. They occupy their hosts for a few days (influenza), for a few weeks (measles), or even lifelong (HCV), which…

种群与进化 · 定量生物学 2020-05-01 Alexander Lange

Mosquitoes are vectors of many human diseases. In particular, Aedes \ae gypti (Linnaeus) is the main vector for Chikungunya, Dengue, and Zika viruses in Latin America and it represents a global threat. Public health policies that aim at…

机器学习 · 统计学 2018-05-08 J. M. Scavuzzo , F. Trucco , M. Espinosa , C. B. Tauro , M. Abril , C. M. Scavuzzo , A. C. Frery

Understanding how age-specific social contact patterns and susceptibility influence infectious disease transmission is crucial for accurate epidemic modeling. This study presents an eigenvector-based sensitivity analysis framework to…

种群与进化 · 定量生物学 2025-11-21 Evans Kiptoo Korir , Zsolt Vizi

Motivated by observations in sequence data of herpesviruses, we introduce a multi-locus model for the joint evolution of different genotypes in a virus population that is distributed across a population of hosts. In the model, virus…

种群与进化 · 定量生物学 2025-09-24 Raphael Eichhorn , Cornelia Pokalyuk

We study the early stages of viral infection, and the distribution of times to obtain a persistent infection. The virus population proliferates by entering and reproducing inside a target cell until a sufficient number of new virus…

种群与进化 · 定量生物学 2019-07-11 Carmel Sagi , Michael Assaf

The non-equilibrium phase transition in models for epidemic spreading with long-range infections in combination with incubation times is investigated by field-theoretical and numerical methods. Here the spreading process is modelled by…

统计力学 · 物理学 2007-05-23 Julian Adamek , Michael Keller , Arne Senftleben , Haye Hinrichsen

The reproduction number of deterministic models is an essential quantity to predict whether an epidemic will spread or die out. Thresholds for disease extinction contribute crucial knowledge on disease control, elimination, and mitigation…

种群与进化 · 定量生物学 2013-08-08 Ling Xue , Caterina Scoglio

When an infectious disease propagates throughout society, the incidence function may rise at first due to an increase in pathogenicity and then decrease due to inhibitory effects until it reaches saturation. Effective vaccination and…

动力系统 · 数学 2023-07-11 Sushil Pathak , G. Shirisha , K. Venkata Ratnam

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

种群与进化 · 定量生物学 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

It is preliminarily known that Aedes mosquitoes are very close to humans and their dwellings, also give rises to a broad spectrum of diseases: dengue, yellow fever, chikungunya. In this paper, we explore a multi-age-class model for mosquito…

最优化与控制 · 数学 2017-12-04 Karunia Putra Wijaya , Thomas Goetz , Edy Soewono

We consider multiple diseases spreading in a static Configuration Model network. We make standard assumptions that infection transmits from neighbor to neighbor at a disease-specific rate and infected individuals recover at a…

种群与进化 · 定量生物学 2015-06-11 Joel C. Miller

Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…

Dengue fever is increasing in geographical range, spread by invasion of its vector mosquitoes. The trade in second-hand tires has been implicated as a factor in this process as they act as mobile reservoirs of mosquito eggs and larvae.…

种群与进化 · 定量生物学 2017-01-23 Emilene Pliego Pliego , Jorge Velázquez-Castro , Markus P. Eichhorn , Andrés Fraguela Collar

Age-dependent dynamics is an important characteristic of many infectious diseases. Age-group epidemic models describe the infection dynamics in different age-groups by allowing to set distinct parameter values for each. However, such models…

统计方法学 · 统计学 2017-07-17 Rami Yaari , Itai Dattner , Amit Huppert