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In this paper, we study a phase-space analysis of a mathematical model of tumor growth with an immune response. Mathematical analysis of the model equations with multipoint initial condition, regarding to dissipativity, boundedness of…

组织与器官 · 定量生物学 2018-01-17 Veli Shakhmurov

In this paper, we studied phase-space analysis of a certain mathematical model of tumor growth with an immune responses and chemotherapy therapy. Mathematical modelling of this process is viewed as a potentially powerful tool in the…

动力系统 · 数学 2018-03-15 Veli Shakhmurov , Akif Maharramov , Bunyad Shahmurzada

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

偏微分方程分析 · 数学 2013-06-11 Martin Kohlmann

We consider the problem of the long time dynamics for a diffuse interface model for tumor growth. The model describes the growth of a tumor surrounded by host tissues in the presence of a nutrient and consists in a Cahn-Hilliard-type…

偏微分方程分析 · 数学 2018-10-30 Alain Miranville , Elisabetta Rocca , Giulio Schimperna

In this survey article, a variety of systems modeling tumor growth are discussed. In accordance with the hallmarks of cancer, the described models incorporate the primary characteristics of cancer evolution. Specifically, we focus on…

动力系统 · 数学 2023-03-21 Marvin Fritz

This paper concerns multiphase models of tumor growth in interaction with a surrounding tissue, taking into account also the interplay with diffusible nutrients feeding the cells. Models specialize in nonlinear systems of possibly…

数学物理 · 物理学 2017-01-20 Andrea Tosin

We investigate the dynamics of a nonlinear model for tumor growth within a cellular medium. In this setting the "tumor" is viewed as a multiphase flow consisting of cancerous cells in either proliferating phase or quiescent phase and a…

偏微分方程分析 · 数学 2015-03-31 Donatella Donatelli , Konstantina Trivisa

Cancer is a very complex phenomenon that involves many different scales and situations. In this paper we consider a free boundary problem describing the evolution of a tumor colony and we derive a new asymptotic model for tumor growth. We…

偏微分方程分析 · 数学 2025-04-15 Rafael Granero-Belinchón , Martina Magliocca

We present a multiphase mathematical model for tumor growth which incorporates the remodeling of the extracellular matrix and describes the formation of fibrotic tissue by tumor cells. We also detail a full qualitative analysis of the…

数学物理 · 物理学 2010-08-09 Andrea Tosin , Luigi Preziosi

This paper provides a unified mathematical analysis of a family of non-local diffuse interface models for tumor growth describing evolutions driven by long-range interactions. These integro-partial differential equations model cell-to-cell…

偏微分方程分析 · 数学 2021-07-07 Luca Scarpa , Andrea Signori

We propose a model for describing the growth on an untreated tumor, which is characterized in a simple way by a minimal number of parameters with a well-defined physical interpretation. The model is motivated by invoking the Master Equation…

种群与进化 · 定量生物学 2007-05-23 José F. Nieves , Marcelo R. Ubriaco

We consider two minimal mathematical models for cancer dynamics and self-adaptation. We aim to capture the interplay between the rapid progression of cancer growth and the possibility to leverage and enhance self-adaptive defense mechanisms…

适应与自组织系统 · 物理学 2025-03-27 Christian Kuehn

We investigate the dynamics of a nonlinear system modeling tumor growth with drug application. The tumor is viewed as a mixture consisting of proliferating, quiescent and dead cells as well as a nutrient in the presence of a drug. The…

偏微分方程分析 · 数学 2015-06-22 Donatella Donatelli , Konstantina Trivisa

We study a tumor growth model in two space dimensions, where proliferation of the tumor cells leads to expansion of the tumor domain and migration of surrounding normal tissues into the exterior vacuum. The model features two moving…

偏微分方程分析 · 数学 2020-02-11 Inwon Kim , Jiajun Tong

In this paper we propose an ecological resilience point of view on cancer. This view is based on the analysis of a simple ODE model for the interactions between cancer and normal cells. The model presents two regimes for tumor growth. In…

种群与进化 · 定量生物学 2016-09-01 Artur C. Fassoni , Hyun M. Yang

In this paper we present a study of local dynamics of the growth of cancer tumor and healthy cells considering the presence of nutrients in the system. We also analyze the evolution of system if we take indirectly into account the level of…

生物物理 · 物理学 2019-01-29 Cristian C. Pérez Águila , Maura Cárdenas G. , J. Fernando Rojas

In this paper, we conduct a thorough mathematical analysis of a tumor growth model with treatments. The model is a system describing the evolution of metastatic tumors and the number of cells present in a primary tumor. The former evolution…

偏微分方程分析 · 数学 2022-05-25 Slah Eddin Ben Abdeljalil , Atef Ben Essid , Saloua Mani Aouadi

In this paper a macroscopic model of tumor cord growth is developed, relying on the mathematical theory of deformable porous media. Tumor is modeled as a saturated mixture of proliferating cells, extracellular fluid and extracellular…

数学物理 · 物理学 2010-11-09 Andrea Tosin

We consider a phase-field model of prostate cancer growth with chemotherapy and antiangiogenic therapy effects which is introduced in [2]. It is comprised of phase-field equation to describe tumor growth, which is coupled to a…

偏微分方程分析 · 数学 2020-10-22 Tania Biswas , Elisabetta Rocca

We give a very short introduction to discrete and continuum models for the evolutionary and spatial dynamics of cancer through two case studies: a model for the evolutionary dynamics of cancer cells under cytotoxic therapy and a model for…

组织与器官 · 定量生物学 2019-11-07 Tommaso Lorenzi , Fiona R. Macfarlane , Chiara Villa
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