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We consider the SEIR compartmental epidemic model subject to state and input constraints (a cap on the proportion of infectious individuals and limits on the allowed social distancing and quarantining measures, respectively). We present a…

最优化与控制 · 数学 2024-06-11 Willem Esterhuizen , Philipp Sauerteig , Stefan Streif , Karl Worthmann

At the time of writing, the ongoing COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had already resulted in more than thirty-two million cases infected and more than one million deaths worldwide.…

最优化与控制 · 数学 2023-03-22 Chung-Han Hsieh

In this paper, we consider the problem of minimum-time optimal control for a dynamical system with initial state uncertainties and propose a sequential convex programming (SCP) solution framework. We seek to minimize the expected terminal…

最优化与控制 · 数学 2024-09-17 Kazuya Echigo , Abhishek Cauligi , Behçet Açıkmeşe

Stochastic epidemic models provide an interpretable probabilistic description of the spread of a disease through a population. Yet, fitting these models to partially observed data is a notoriously difficult task due to intractability of the…

统计计算 · 统计学 2022-10-21 Raphael Morsomme , Jason Xu

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

种群与进化 · 定量生物学 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

We propose a dynamical model for describing the spread of epidemics. This model is an extension of the SIQR (susceptible-infected-quarantined-recovered) and SIRP (susceptible-infected-recovered-pathogen) models used earlier to describe…

物理与社会 · 物理学 2022-12-08 S. P. Lukyanets , I. S. Gandzha , O. V. Kliushnichenko

The non-population conserving SIR (SIR-NC) model to describe the spread of infections in a community is proposed and studied. Unlike the standard SIR model, SIR-NC does not assume population conservation. Although similar in form to the…

最优化与控制 · 数学 2020-11-06 Vivek S. Borkar , D. Manjunath

We present a control framework for stochastic compartmental models in epidemiology. In this framework, rather than directly controlling the stochastic system, we perform optimal control of an associated Fokker-Planck equation, with the goal…

最优化与控制 · 数学 2026-04-06 Christian Parkinson , Souvik Roy

In this paper we study the diffusion of an SIS-type epidemics on a network under the presence of a random environment, that enters in the definition of the infection rates of the nodes. Accordingly, we model the infection rates in the form…

概率论 · 数学 2016-07-25 Stefano Bonaccorsi , Stefania Ottaviano

Pandemics can bring a range of devastating consequences to public health and the world economy. Identifying the most effective control strategies has been the imperative task all around the world. Various public health control strategies…

系统与控制 · 电气工程与系统科学 2021-03-29 Zhe Xu , Xiaoming Duan

In this paper, we study a novel control method for a generalized SIS epidemic process. In particular, we use predictive control to design optimal protective resource distribution strategies which balance the need to eliminate the epidemic…

最优化与控制 · 数学 2018-08-17 Nicholas J. Watkins , George J. Pappas

The rapid worldwide spread of the severe acute respiratory syndrome (SARS) demonstrated the potential threat an infectious disease poses in a closely interconnected and interdependent world. Here we introduce a probabilistic model which…

无序系统与神经网络 · 物理学 2009-11-10 L. Hufnagel , D. Brockmann , T. Geisel

We present an exact analytical solution to a one-dimensional model of the Susceptible-Infected-Recovered (SIR) epidemic type, with infection rates dependent on nearest-neighbor occupations. We use a quantum mechanical approach, transforming…

统计力学 · 物理学 2015-05-30 H. Thomas Williams , Irina Mazilu , Dan Mazilu

In this study, a new and natural way of constructing a stochastic Susceptible-Infected-Susceptible (SIS) model is proposed. This approach is natural in the sense that the disease transmission rate, $\beta$, is substituted with a generic,…

概率论 · 数学 2025-11-07 Berk Tan Perçin

The study of epidemic models plays an important role in mathematical epidemiology. There are many researches on epidemic models using ordinary differential equations, partial differential equations or stochastic differential equations. In…

概率论 · 数学 2023-03-10 Yuqi Li , Lihua Zhang

This article considers the stochastic optimal control of discrete-time linear systems subject to (possibly) unbounded stochastic disturbances, hard constraints on the manipulated variables, and joint chance constraints on the states. A…

最优化与控制 · 数学 2017-06-23 Joel A. Paulson , Edward A. Buehler , Richard D. Braatz , Ali Mesbah

This paper presents a real time, data driven decision support framework for epidemic control. We combine a compartmental epidemic model with sequential Bayesian inference and reinforcement learning (RL) controllers that adaptively choose…

统计方法学 · 统计学 2025-11-25 Giacomo Iannucci , Petros Barmpounakis , Alexandros Beskos , Nikolaos Demiris

Model Predictive Control (MPC) is widely used to achieve performance objectives, while enforcing operational and safety constraints. Despite its high performance, MPC often demands significant computational resources, making it challenging…

最优化与控制 · 数学 2025-01-24 Mohsen Amiri , Mehdi Hosseinzadeh

Motivated by recent epidemic outbreaks, including those of COVID-19, we solve the canonical problem of calculating the dynamics and likelihood of extensive outbreaks in a population within a large class of stochastic epidemic models with…

种群与进化 · 定量生物学 2022-01-31 Jason Hindes , Michael Assaf , Ira B. Schwartz

The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

种群与进化 · 定量生物学 2020-11-17 Christian Gourieroux , Yang Lu