相关论文: On the relative role of different age groups durin…
Acute respiratory diseases are transmitted over networks of social contacts. Large-scale simulation models are used to predict epidemic dynamics and evaluate the impact of various interventions, but the contact behavior in these models is…
School environments are thought to play an important role in the community spread of airborne infections (e.g., influenza) because of the high mixing rates of school children. The closure of schools has therefore been proposed as efficient…
Little quantitative information is available on the mixing patterns of children in school environments. Describing and understanding contacts between children at school would help quantify the transmission opportunities of respiratory…
Age-dependent dynamics is an important characteristic of many infectious diseases. Age-group epidemic models describe the infection dynamics in different age-groups by allowing to set distinct parameter values for each. However, such models…
Voluntary vaccination is essential to protect oneself from infection and suppress the spread of infectious diseases. Voluntary vaccination behavior is influenced by factors such as age and interaction patterns. Differences in health…
Early on during a pandemic, vaccine availability is limited, requiring prioritisation of different population groups. Evaluating vaccine allocation is therefore a crucial element of pandemics response. In the present work, we develop a…
The way diseases spread through schools, epidemics through countries, and viruses through the Internet is crucial in determining their risk. Although each of these threats has its own characteristics, its underlying network determines the…
This study documents the relationship between computer skills/digital literacy and influenza vaccination take-up among older adults in Europe during and after the COVID-19 pandemic. Using data from the Survey of Health, Aging and Retirement…
The state of health of patients is typically not characterized by a single disease alone but by multiple (comorbid) medical conditions. These comorbidities may depend strongly on age and gender. We propose a specific phenomenological…
The vaccination against ongoing epidemics is seldom compulsory but remains one of the most classical means to fight epidemic propagation. However recent debates concerning the innocuity of vaccines and their risk with respect to the risk of…
Influenza A is a serious disease that causes significant morbidity and mortality, and vaccines against the seasonal influenza disease are of variable effectiveness. In this paper, we discuss use of the $p_{\rm epitope}$ method to predict…
The response of many governments to the COVID-19 pandemic has involved measures to control within- and between-household transmission, providing motivation to improve understanding of the absolute and relative risks in these contexts. Here,…
Aim: To assess the frequency of secondary transmissions of primary pneumonic plague relative to the onset of fever. Methods: A simple backcalculation method was employed to estimate the frequency of secondary transmissions relative to…
Seasonal influenza presents an ongoing challenge to public health. The rapid evolution of the flu virus necessitates annual vaccination campaigns, but the decision to get vaccinated or not in a given year is largely voluntary, at least in…
How important is resource depletion (e.g. depletion of target cells) in controlling infection within a host? And how can we distinguish between resource depletion and other mechanisms that may contribute to decline of pathogen load or lead…
Waning immunity and reinfection are critical features of many infectious diseases, but epidemiological models often fail to capture the intricate interaction between an individual's history of immunity and their current infection status;…
We investigate the problem of estimating the distribution of the individual reproduction number governing the COVID-19 pandemic. Under the assumption that this random variable follows a Negative Binomial distribution, we focus on…
The complex interplay between population movements in space and non-homogeneous mixing patterns have so far hindered the fundamental understanding of the conditions for spatial invasion through a general theoretical framework. To address…
As infectious disease outbreaks emerge, public health agencies often enact vaccination and social distancing measures to slow transmission. Their success depends on not only strategies and resources, but also public adherence. Individual…
Several important aspects related to SARS-CoV-2 transmission are not well known due to a lack of appropriate data. However, mathematical and computational tools can be used to extract part of this information from the available data, like…