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The formula for the probability of fixation of a new mutation is widely used in theoretical population genetics and molecular evolution. Here we derive a series of identities, inequalities and approximations for the exact probability of…

种群与进化 · 定量生物学 2015-03-10 David M. McCandlish , Charles L. Epstein , Joshua B. Plotkin

A mutator is an allele that increases the mutation rate throughout the genome by disrupting some aspect of DNA replication or repair. Mutators that increase the mutation rate by the order of 100 fold have been observed to spontaneously…

种群与进化 · 定量生物学 2008-12-31 C. Scott Wylie , Cheol-Min Ghim , David A. Kessler , Herbert Levine

In nature, most microbial populations have complex spatial structures that can affect their evolution. Evolutionary graph theory predicts that some spatial structures modelled by placing individuals on the nodes of a graph affect the…

种群与进化 · 定量生物学 2024-12-30 Alia Abbara , Lisa Pagani , Celia García-Pareja , Anne-Florence Bitbol

We demonstrate a vast expansion of the theory of evolutionary stability to finite populations with mutation, connecting the theory of the stationary distribution of the Moran process with the Lyapunov theory of evolutionary stability. We…

动力系统 · 数学 2020-02-11 Marc Harper , Dashiell Fryer

The Moran process, as studied by [Lieberman, E., Hauert, C. and Nowak, M. Evolutionary dynamics on graphs. Nature 433, pp. 312-316 (2005)], is a stochastic process modeling the spread of genetic mutations in populations. In this process,…

种群与进化 · 定量生物学 2021-07-27 Themistoklis Melissourgos , Sotiris Nikoletseas , Christoforos Raptopoulos , Paul Spirakis

We define the incentive process, a natural generalization of the Moran process incorporating evolutionary updating mechanisms corresponding to well-known evolutionary dynamics, such as the logit, projection, and best-reply dynamics.…

动力系统 · 数学 2013-12-04 Marc Harper , Dashiell Fryer

In evolutionary processes, population structure has a substantial effect on natural selection. Here, we analyze how motion of individuals affects constant selection in structured populations. Motion is relevant because it leads to changes…

种群与进化 · 定量生物学 2017-10-10 Madison S. Krieger , Alex McAvoy , Martin A. Nowak

Temporal environmental variations are ubiquitous in nature, yet most of the theoretical works in population genetics and evolution assume fixed environment. Here we analyze the effect of variations in carrying capacity on the fate of a…

种群与进化 · 定量生物学 2019-12-16 Immanuel Meyer , Nadav M. Shnerb

The multi-type Moran process is an evolutionary process on a connected graph $G$ in which each vertex has one of $k$ types and, in each step, a vertex $v$ is chosen to reproduce its type to one of its neighbours. The probability of a vertex…

数据结构与算法 · 计算机科学 2023-03-15 Leslie Ann Goldberg , Marc Roth , Tassilo Constantin Schwarz

We study the dynamics of a population subject to selective pressures, evolving either on RNA neutral networks or in toy fitness landscapes. We discuss the spread and the neutrality of the population in the steady state. Different limits…

种群与进化 · 定量生物学 2009-11-13 Sumedha , Olivier C Martin , Luca Peliti

The environment in which a population evolves can have a crucial impact on selection. We study evolutionary dynamics in finite populations of fixed size in a changing environment. The population dynamics are driven by birth and death…

种群与进化 · 定量生物学 2014-09-01 Peter Ashcroft , Philipp M Altrock , Tobias Galla

In this paper, we study the absorption and fixation times for evolutionary processes on graphs, under different updating rules. While in Moran process a single neighbour is randomly chosen to be replaced, in proliferation processes other…

种群与进化 · 定量生物学 2026-01-16 Fernando Alcalde Cuesta , Gustavo Guerberoff , Álvaro Lozano Rojo

Population structure and spatial heterogeneity are integral components of evolutionary dynamics, in general, and of evolution of cooperation, in particular. Structure can promote the emergence of cooperation in some populations and suppress…

种群与进化 · 定量生物学 2017-10-10 Yu-Ting Chen , Alex McAvoy , Martin A. Nowak

Many mathematical models of evolution assume that all individuals experience the same environment. Here, we study the Moran process in heterogeneous environments. The population is of finite size with two competing types, which are exposed…

种群与进化 · 定量生物学 2018-12-19 Kamran Kaveh , Alex McAvoy , Martin A. Nowak

In subdivided populations, migration acts together with selection and genetic drift and determines their evolution. Building up on a recently proposed method, which hinges on the emergence of a time scale separation between local and global…

种群与进化 · 定量生物学 2015-03-24 Pierangelo Lombardo , Andrea Gambassi , Luca Dall'Asta

Stronger selection implies faster evolution---that is, the greater the force, the faster the change. This apparently self-evident proposition, however, is derived under the assumption that genetic variation within a population is primarily…

种群与进化 · 定量生物学 2017-08-18 Masahiko Ueda , Nobuto Takeuchi , Kunihiko Kaneko

We study the large population limit of the Moran process, assuming weak-selection, and for different scalings. Depending on the particular choice of scalings, we obtain a continuous model that may highlight the genetic-drift (neutral…

种群与进化 · 定量生物学 2013-01-21 Fabio A. C. C. Chalub , Max O. Souza

Evolutionary game theory is a mathematical approach to studying how social behaviors evolve. In many recent works, evolutionary competition between strategies is modeled as a stochastic process in a finite population. In this context, two…

种群与进化 · 定量生物学 2017-08-16 Christine Sample , Benjamin Allen

One of the most fundamental concepts of evolutionary dynamics is the "fixation" probability, i.e. the probability that a mutant spreads through the whole population. Most natural communities are geographically structured into habitats…

种群与进化 · 定量生物学 2013-05-01 Bahram Houchmandzadeh , Marcel Vallade

In stochastic dynamical systems, different concepts of stability can be obtained in different limits. A particularly interesting example is evolutionary game theory, which is traditionally based on infinite populations, where strict Nash…

种群与进化 · 定量生物学 2007-05-23 Arne Traulsen , Jorge M. Pacheco , Lorens A. Imhof