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相关论文: Analysis of Hepatitis C Viral Dynamics Using Latin…

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A mathematical modeling of Hepatitis C Virus (HCV) dynamics has been presented in this paper. The proposed model, which involves four coupled ordinary differential equations, describes the interaction of target cells (hepatocytes), infected…

细胞行为 · 定量生物学 2011-05-19 Sandip Banerjee , Ram Keval , S. Gakkhar

In this paper, a mathematical analysis of the global dynamics of a viral infection model in vivo is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both extracellular and intracellular…

种群与进化 · 定量生物学 2020-11-13 Alexis Nangue , Alan D. Rendall , Brice Kammegne Tcheugam , Patrick Steve Kamdem Simo

We examine two models for hepatitis C viral (HCV) dynamics, one for monotherapy with interferon (IFN) and the other for combination therapy with IFN and ribavirin. Optimal therapy for both the models is determined using the steepest…

定量方法 · 定量生物学 2011-09-06 Gaurav Pachpute , Siddhartha P. Chakrabarty

In this paper, a mathematical analysis of the global dynamics of a partial differential equation viral infection cellular model is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both…

偏微分方程分析 · 数学 2021-11-08 Alexis Nangue , Bruno Nde Tchiffo

The aims of this work is to analyse of the global stability of the extended model of hepatitis C virus(HCV) infection with cellular proliferation, spontaneous cure and hepatocyte homeostasis. We first give general information about…

动力系统 · 数学 2019-05-08 Alexis Nangue , Cyprien Fokoue , Raoue Poumeni

This paper carries out an analysis of the global properties of solutions of an in-host model of hepatitis C for general values of its parameters. A previously unknown stable steady state on the boundary of the positive orthant is exhibited.…

种群与进化 · 定量生物学 2022-06-13 Alexis Nangue , Alan D. Rendall

We investigate the dynamics of the hepatitis B virus by integrating variable-order calculus and discrete analysis. Specifically, we utilize the Caputo variable-order difference operator in this study. To establish the existence and…

种群与进化 · 定量生物学 2024-05-27 Meriem Boukhobza , Amar Debbouche , Lingeshwaran Shangerganesh , Delfim F. M. Torres

This study develops and analyzes a stochastic differential equation (SDE) model for the dynamics of hepatitis B virus (HBV) infection. While deterministic frameworks have yielded important insights into viral behavior, they cannot…

动力系统 · 数学 2025-10-03 Abdallah Alsammani

This study presents an improved mathematical model for Hepatitis B Virus (HBV) transmission dynamics by investigating autonomous and nonautonomous cases. The novel model incorporates the effects of medical treatment, allowing for a more…

动力系统 · 数学 2025-05-15 Abdallah Alsammani

In this paper, we present the global analysis of a HCV model under therapy. We prove that the solutions with positive initial values are global, positive, bounded and not display periodic orbits. In addition, we show that the model is…

种群与进化 · 定量生物学 2019-05-09 Alexis Nangue

This paper considers a mathematical model based on the transmission dynamics of hepatitis C virus (HCV) infection. In addition to the usual compartments for susceptible, exposed, and infected individuals, this model includes compartments…

种群与进化 · 定量生物学 2017-12-25 Daniah Tahir , Abid Ali Lashari , Kazeem Oare Okosun

Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). In this paper, the transmission dynamics of hepatitis B is formulated with a mathematical model with considerations of different classes of…

种群与进化 · 定量生物学 2023-06-01 Blessing O. Emerenini , Simeon C. Inyama

We study within-host HIV dynamics using a three--component nonlinear ordinary differential equation model for healthy CD4$^{+}$ T cells, infected CD4$^{+}$ T cells, and free virus. In addition to the baseline model without treatment, we…

数值分析 · 数学 2025-12-16 Abdul Rab

We will study a mathematical model of the human immunodeficiency virus (HIV) infection in the presence of combination therapy that includes within-host infectious dynamics. The deterministic model requires us to analyze asymptotic stability…

种群与进化 · 定量生物学 2017-09-04 Majid Jaberi Douraki

Decision-makers frequently must choose a single action from a finite set of alternatives -- for example, physicians selecting a treatment, investors choosing a portfolio risk level, or judges determining sentences. To improve outcomes,…

应用统计 · 统计学 2026-05-19 Raphaël Langevin

This research gives a thorough examination of an HIV infection model that includes quiescent cells and immune response dynamics in the host. The model, represented by a system of ordinary differential equations, captures the complex…

种群与进化 · 定量生物学 2025-03-04 Ibrahim Nali , Attila Dénes , Abdessamad Tridane , Xueyong Zhou

We consider the basic model of virus dynamics in the modeling of Human Immunodeficiency Virus (HIV), in a 2D heterogenous environment. It consists of two ODEs for the non-infected and infected $CD_4^+$ $T$ lymphocytes, $T$ and $I$, and a…

动力系统 · 数学 2009-05-14 Claude-Michel Brauner , Danaelle Jolly , Luca Lorenzi , Rodolphe Thiebaut

We consider a Human Immunodeficiency Virus (HIV) model with a logistic growth term and continue the analysis of the previous article [6]. We now take the viral diffusion in a two-dimensional environment. The model consists of two ODEs for…

偏微分方程分析 · 数学 2012-11-02 Claude-Michel Brauner , Xinyue Fan , Luca Lorenzi

In this paper we study a model of HCV with mitotic proliferation, a saturation infection rate and a discrete intracellular delay: the delay corresponds to the time between infection of a infected target hepatocytes and production of new HCV…

动力系统 · 数学 2014-03-13 E. Avila-Vales , N. Chan-Chí , G. García-Almeida , C. Vargas-De-León

In this paper we present a delay induced model for hepatitis C virus incorporating the healthy and infected hepatocytes as well as infectious and noninfectious virions. The model is mathematically analyzed and characterized, both for the…

动力系统 · 数学 2014-03-11 Sandip Banerjee , Ram Keval , Sunita Gakkhar
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