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相关论文: The algebra of the general Markov model on phyloge…

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We present a method of dimensional reduction for the general Markov model of sequence evolution on a phylogenetic tree. We show that taking certain linear combinations of the associated random variables (site pattern counts) reduces the…

种群与进化 · 定量生物学 2016-11-29 Jeremy G Sumner

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees relating species. Along branches, sequence evolution is modelled using a continuous-time Markov process characterised by an instantaneous rate…

Methods of phylogenetic inference use more and more complex models to generate trees from data. However, even simple models and their implications are not fully understood. Here, we investigate the two-state Markov model on a tripod tree,…

种群与进化 · 定量生物学 2011-12-06 Steffen Klaere , Volkmar Liebscher

Inference of evolutionary trees and rates from biological sequences is commonly performed using continuous-time Markov models of character change. The Markov process evolves along an unknown tree while observations arise only from the tips…

统计理论 · 数学 2008-02-01 Elizabeth S. Allman , Cecile Ane , John A. Rhodes

The evolution of molecular and phenotypic traits is commonly modelled using Markov processes along a phylogeny. This phylogeny can be a tree, or a network if it includes reticulations, representing events such as hybridization or admixture.…

种群与进化 · 定量生物学 2024-08-28 Benjamin Teo , Paul Bastide , Cécile Ané

In the last decade, some algebraic tools have been successfully applied to phylogenetic reconstruction. These tools are mainly based on the knowledge of equations describing algebraic varieties associated to phylogenetic trees evolving…

种群与进化 · 定量生物学 2025-07-04 Marta Casanellas , Jesús Fernández-Sánchez

The evolution of aligned DNA sequence sites is generally modeled by a Markov process operating along the edges of a phylogenetic tree. It is well known that the probability distribution on the site patterns at the tips of the tree…

种群与进化 · 定量生物学 2013-10-15 Benny Chor , Mike Steel

Modelling the substitution of nucleotides along a phylogenetic tree is usually done by a hidden Markov process. This allows to define a distribution of characters at the leaves of the trees and one might be able to obtain polynomial…

种群与进化 · 定量生物学 2020-10-12 Marta Casanellas , Jesús Fernández-Sánchez , Marina Garrote-López

We studied how to obtain a distribution for the number of ancestors in species of sexual reproduction. Present models concentrate on the estimation of distributions repetitions of ancestors in genealogical trees. It has been shown that is…

生物物理 · 物理学 2019-09-12 M. Caruso , C. Jarne

We consider the problem of uniformly generating a spanning tree, of a connected undirected graph. This process is useful to compute statistics, namely for phylogenetic trees. We describe a Markov chain for producing these trees. For cycle…

数据结构与算法 · 计算机科学 2020-07-08 Luís M. S. Russo , Andreia Sofia Teixeira , Alexandre P Francisco

The general Markov model of the evolution of biological sequences along a tree leads to a parameterization of an algebraic variety. Understanding this variety and the polynomials, called phylogenetic invariants, which vanish on it, is a…

代数几何 · 数学 2007-06-13 Elizabeth S. Allman , John A. Rhodes

In recent years, a number of methods have been developed to infer complex demographic histories, especially historical population size changes, from genomic sequence data. Coalescent Hidden Markov Models have proven to be particularly…

种群与进化 · 定量生物学 2017-10-10 Alexey Miroshnikov , Matthias Steinrücken

We consider a class of density-dependent branching processes which generalises exponential, logistic and Gompertz growth. A population begins with a single individual, grows exponentially initially, and then growth may slow down as the…

概率论 · 数学 2022-04-11 David Cheek

We introduce some natural families of distributions on rooted binary ranked plane trees with a view toward unifying ideas from various fields, including macroevolution, epidemiology, computational group theory, search algorithms and other…

组合数学 · 数学 2017-08-22 Sean Cleary , Mareike Fischer , Robert C. Griffiths , Raazesh Sainudiin

An analysis of the Kimura 3ST model of DNA sequence evolution is given on the basis of its continuous Lie symmetries. The rate matrix commutes with a U(1)xU(1)xU(1) phase subgroup of the group GL(4) of 4x4x4 invertible complex matrices…

种群与进化 · 定量生物学 2013-07-23 J. D. Bashford , P. D. Jarvis , J. G. Sumner , M. A. Steel

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees. Substitutions in sequences are modelled through a continuous-time Markov process, characterised by an instantaneous rate matrix, which standard…

种群与进化 · 定量生物学 2020-07-20 Naomi E. Hannaford , Sarah E. Heaps , Tom M. W. Nye , Tom A. Williams , T. Martin Embley

More than ever, today we are left with the abundance of molecular data outpaced by the advancements of the phylogenomic methods. Especially in the case of presence of many genes over a set of species under the phylogeny question, more…

应用统计 · 统计学 2021-11-29 Ali Amiryousefi

Many of the stochastic models used in inference of phylogenetic trees from biological sequence data have polynomial parameterization maps. The image of such a map --- the collection of joint distributions for a model --- forms the model…

种群与进化 · 定量生物学 2012-12-07 Elizabeth S. Allman , John A. Rhodes , Amelia Taylor

We consider a branching model in discrete time where each individual has a trait in some general state space. Both the reproduction law and the trait inherited by the offsprings may depend on the trait of the mother and the environment. We…

概率论 · 数学 2013-11-26 Vincent Bansaye

The general Markov plus invariable sites (GM+I) model of biological sequence evolution is a two-class model in which an unknown proportion of sites are not allowed to change, while the remainder undergo substitutions according to a Markov…

种群与进化 · 定量生物学 2011-11-10 Elizabeth S. Allman , John A. Rhodes
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