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Cohort studies are of significant importance in the field of healthcare analysis. However, existing methods typically involve manual, labor-intensive, and expert-driven pattern definitions or rely on simplistic clustering techniques that…

机器学习 · 计算机科学 2024-06-21 Qingpeng Cai , Kaiping Zheng , H. V. Jagadish , Beng Chin Ooi , James Yip

The dynamics of fractional population sizes y_i=Y_i/N in homogeneous compartment models with time dependent total population N is analyzed. Assuming constant per capita birth and death rates the vector field Y_i'=V_i(Y) naturally projects…

种群与进化 · 定量生物学 2023-04-17 Florian Nill

Bayesian models are increasing fit to large administrative data sets and then used to make individualized recommendations. For instance, Medicare's Hospital Compare webpage provides information to patients about specific hospital mortality…

应用统计 · 统计学 2018-04-03 E. I. George , V. Rockova , P. R. Rosenbaum , V. A. Satopaa , J. H. Silber

This paper introduces a new fixed effects estimator for linear panel data models with clustered time patterns of unobserved heterogeneity. The method avoids non-convex and combinatorial optimization by combining a preliminary consistent…

计量经济学 · 经济学 2025-04-21 Martin Mugnier

Machine learning models that aim to predict dementia onset usually follow the classification methodology ignoring the time until an event happens. This study presents an alternative, using survival analysis within the context of machine…

机器学习 · 计算机科学 2023-06-21 Daniel Stamate , Henry Musto , Olesya Ajnakina , Daniel Stahl

A class of multivariate mixed survival models for continuous and discrete time with a complex covariance structure is introduced in a context of quantitative genetic applications. The methods introduced can be used in many applications in…

应用统计 · 统计学 2014-05-06 Rafael Pimentel Maia , Per Madsen , Rodrigo Labouriau

In this paper, we present a technique for parameterizing Leslie transition matrices from simple age and sex population counts, using an implementation of "Wood's Method" [wood]; these matrices can forecast population by age and sex (the…

种群与进化 · 定量生物学 2012-04-24 W. Webb Sprague

We consider first the mixed discrete-continuous scheme of observation in multistate models; this is a classical pattern in epidemiology because very often clinical status is assessed at discrete visit times while times of death or other…

统计理论 · 数学 2008-12-18 Daniel Commenges , Anne Gégout-Petit

This article describes a method to estimate the mortality rate ratio R from current status data with duration in a chronic condition in case the general mortality of the overall population is known. Apart from the general mortality, the…

统计方法学 · 统计学 2022-10-21 Ralph Brinks

Many spreading processes in our real-life can be considered as a complex contagion, and the linear threshold (LT) model is often applied as a very representative model for this mechanism. Despite its intensive usage, the LT model suffers…

物理与社会 · 物理学 2020-08-18 Yijun Ran , Xiaomin Deng , Xiaomeng Wang , Tao Jia

Joint analysis of multi-omic single-cell data across cohorts has significantly enhanced the comprehensive analysis of cellular processes. However, most of the existing approaches for this purpose require access to samples with complete…

机器学习 · 计算机科学 2024-05-21 Marianne Arriola , Weishen Pan , Manqi Zhou , Qiannan Zhang , Chang Su , Fei Wang

This article investigates the model-robustness of fixed-effects models for analyzing a broad class of longitudinal cluster trials (CTs) such as stepped-wedge, parallel-with-baseline and crossover designs, encompassing both randomized (CRTs)…

统计方法学 · 统计学 2026-04-10 Kenneth M. Lee , Fan Li

I present three types of applications of generalized additive models (GAMs) to COVID-19 mortality rates in the US for the purpose of advancing methods to document inequities with respect to which communities suffered disproportionate…

应用统计 · 统计学 2022-12-01 Christian Testa

In a recent article in PNAS, Case and Deaton show a figure illustrating "a marked increase in the all-cause mortality of middle-aged white non-Hispanic men and women in the United States between 1999 and 2013." The authors state that their…

应用统计 · 统计学 2016-04-27 Andrew Gelman , Jonathan Auerbach

Several collective risk models have recently been proposed by relaxing the widely used but controversial assumption of independence between claim frequency and severity. Approaches include the bivariate copula model, random effect model,…

应用统计 · 统计学 2019-06-11 Rosy Oh , Jae Youn Ahn , Woojoo Lee

When modeling sub-national mortality rates, it is important to incorporate any possible correlation among sub-populations to improve forecast accuracy. Moreover, forecasts at the sub-national level should aggregate consistently across the…

应用统计 · 统计学 2020-11-17 Han Lin Shang , Yang Yang

Cohort studies employ pairwise measures of association to quantify dependencies among conditions and exposures. To reliably use these measures to draw conclusions about the underlying association strengths requires that the measures be…

定量方法 · 定量生物学 2017-05-30 Venkateshan Kannan , Kristina Alexandersson , Jesper Tegner

Since the beginning of the COVID-19 pandemic, many dashboards have emerged as useful tools to monitor the evolution of the pandemic, inform the public, and assist governments in decision making. Our goal is to develop a globally applicable…

We propose a new method for modelling simple longitudinal data. We aim to do this in a flexible manner (without restrictive assumptions about the shapes of individual trajectories), while exploiting structural similarities between the…

统计方法学 · 统计学 2024-09-24 Helen Ogden

There has been growing interest on forecasting mortality. In this article, we propose a novel dynamic Bayesian approach for modeling and forecasting the age-at-death distribution, focusing on a three-components mixture of a Dirac mass, a…

应用统计 · 统计学 2021-12-20 Emanuele Aliverti , Stefano Mazzuco , Bruno Scarpa