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The reduced 1D Poisson-Nernst-Planck (PNP) model of artificial nanopores in the presence of a permanent charge on the channel wall is studied. More specifically, we consider the limit where the channel length exceed much the Debye screening…

化学物理 · 物理学 2008-11-23 I. D. Kosińska , I. Goychuk , M. Kostur , G. Schmid , P. Hänggi

The Poisson-Nernst-Planck (PNP) system is a standard model for describing ion transport. In many applications, e.g., ions in biological tissues, the presence of thin boundary layers poses both modelling and computational challenges. In a…

生物物理 · 物理学 2018-06-22 Zilong Song , Xiulei Cao , Huaxiong Huang

Ion flow in charged nanopores is strongly influenced by the ratio of the Debye length to the pore radius. We investigate the asymptotic behaviour of solutions to the Poisson-Nernst-Planck (PNP) system in narrow pore like geometries and…

偏微分方程分析 · 数学 2019-04-10 B. Matejczyk , J. -F. Pietschmann , G. Richardson , M. -T. Wolfram

In this paper, we propose and validate a two-species Multiscale model for a Poisson-Nernst-Planck (PNP) system, focusing on the correlated motion of positive and negative ions under the influence of a trap. Specifically, we aim to model…

数值分析 · 数学 2026-04-28 Clarissa Astuto , Giovanni Russo

The Poisson-Nernst-Planck (PNP) system is a widely accepted model for simulation of ionic channels. In this paper, we design, analyze, and numerically validate a second order unconditional positivity-preserving scheme for solving a reduced…

数值分析 · 数学 2019-10-01 Hailiang Liu , Wumaier Maimaitiyiming

The molecular mechanism of ion channel gating and substrate modulation is elusive for many voltage gated ion channels, such as eukaryotic sodium ones. The understanding of channel functions is a pressing issue in molecular biophysics and…

生物大分子 · 定量生物学 2016-11-15 Duan Chen , Guowei Wei

A macroscopic model to describe the dynamics of ion transport in ion channels is the Poisson-Nernst-Planck(PNP) equations. In this paper, we develop a finite-difference method for solving PNP equations, which is second-order accurate in…

数值分析 · 数学 2013-03-18 Allen Flavell , Michael Machen , Bob Eisenberg , Chun Liu , Xiaofan Li

The model reduction of a mesoscopic kinetic dynamics to a macroscopic continuum dynamics has been one of the fundamental questions in mathematical physics since Hilbert's time. In this paper, we consider a diagram of the diffusion limit…

数值分析 · 数学 2020-09-29 Jae Yong Lee , Jin Woo Jang , Hyung Ju Hwang

Ion transport through narrow channels is described by the coupled Poisson--Nernst--Planck--Stokes equations (PNPS) on a continuum scale. However, direct numerical simulations in two or three dimensions of boundary value problems for small…

偏微分方程分析 · 数学 2026-03-10 Christine Keller , Andreas Münch , Barbara Wagner

In this paper we propose a computational framework for the investigation of the correlated motion between positive and negative ions exposed to the attraction of a bubble surface that mimics the (oscillating) cell membrane. The correlated…

Effective Poisson-Nernst-Planck (PNP) equations are derived for macroscopic ion transport in charged porous media under periodic fluid flow by an asymptotic multi-scale expansion with drift. The microscopic setting is a two-component…

数学物理 · 物理学 2014-07-16 Markus Schmuck , Martin Z. Bazant

The main goal of this work is to examine the qualitative effect of ion sizes via a steady-state boundary value problem. We study a one-dimensional version of a Poisson-Nernst-Planck system with a local hard-sphere potential model for ionic…

数学物理 · 物理学 2022-03-18 Weishi Liu , Hamid Mofidi

The Poisson--Nernst--Planck (PNP) equations have been widely applied to describe ionic transport in ion channels, nanofluidic devices, and many electrochemical systems. Despite their wide applications, the PNP equations fail in predicting…

统计力学 · 物理学 2018-01-03 Farjana Siddiqua , Zhongming Wang , Shenggao Zhou

We consider the compressible Poisson-Nernst-Planck-Navier-Stokes (PNPNS) system of equations, governing the transport of charged particles under the influence of the self-consistent electrostatic potential, in a three-dimensional bounded…

偏微分方程分析 · 数学 2024-10-03 Daniel Marroquin , Dehua Wang

With a small parameter $\epsilon$, Poisson-Nernst-Planck (PNP) systems over a finite one-dimensional (1D) spatial domain have steady state solutions, called 1D boundary layer solutions, which profiles form boundary layers near boundary…

偏微分方程分析 · 数学 2015-06-30 Chia-Yu Hsieh , Tai-Chia Lin

In this paper, we design, analyze, and numerically validate positive and energy-dissipating schemes for solving the time-dependent multi-dimensional system of Poisson-Nernst-Planck (PNP) equations, which has found much use in the modeling…

数值分析 · 数学 2020-02-24 Hailiang Liu , Wumaier Maimaitiyiming

The non-equilibrium steady states of a semi-infinite quasi-one-dimensional univalent binary electrolyte solution, characterised by non-vanishing electric currents, are investigated by means of Poisson-Nernst-Planck (PNP) theory. Exact…

软凝聚态物质 · 物理学 2024-01-09 Markus Bier

In order to describe the dynamics of crowded ions (charged particles), we use an energetic variation approach to derive a modified Poisson-Nernst-Planck (PNP) system which includes an extra dissipation due to the effective velocity…

数学物理 · 物理学 2014-08-01 Chia-Yu Hsieh , YunKyong Hyon , Hijin Lee , Tai-Chia Lin , Chun Liu

Ion transport in biological and synthetic nanochannels is characterized by phenomena such as ion current fluctuations and rectification. Recently, it has been demonstrated that nanofabricated synthetic pores can mimic transport properties…

经典物理 · 物理学 2009-11-13 I. D. Kosińska , I. Goychuk , M. Kostur , G. Schmid , P. Hänggi

In this paper, we investigate the correlated diffusion of two ion species governed by a Poisson-Nernst-Planck (PNP) system. Here we further validate the numerical scheme recently proposed in \cite{astuto2025asymptotic}, where a time…

数值分析 · 数学 2026-04-28 Clarissa Astuto
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