相关论文: A generalized Cahn-Hilliard equation for biologica…
In this paper, the authors study the distributed optimal control of a system of three evolutionary equations involving fractional powers of three selfadjoint, monotone, unbounded linear operators having compact resolvents. The system is a…
A high-order accurate implicit-mesh discontinuous Galerkin framework for wave propagation in single-phase and bi-phase solids is presented. The framework belongs to the embedded-boundary techniques and its novelty regards the spatial…
We consider a model of congestion dynamics with chemotaxis: The density of cells follows a chemical signal it generates, while subject to an incompressibility constraint. The incompressibility constraint results in the formation of patches,…
In this paper, we study the sharp interface limit for solutions of the Cahn-Hilliard equation with disparate mobilities. This means that the mobility function degenerates in one of the two energetically favorable configurations, suppressing…
Multicomponent bilayer structures arise as the ubiquitous plasma membrane in cellular biology and as blends of amphiphilic copolymers used in electrolyte membranes, drug delivery, and emulsion stabilization within the context of synthetic…
We investigate the propagation of chemical fronts arising in Fisher--Kolmogorov--Petrovskii--Piskunov (FKPP) type models in the presence of a steady cellular flow. In the long-time limit, a steadily propagating pulsating front is…
In the present work, we address a class of Cahn-Hilliard equations characterized by a singular diffusion term. The problem is a simplified version with constant mobility of the Cahn-Hilliard-de Gennes model of phase separation in binary,…
We consider a discretized version of the quenched Edwards-Wilkinson model for the propagation of a driven interface through a random field of obstacles. Our model consists of a system of ordinary differential equations on a $d$-dimensional…
We investigate a diffuse-interface model that describes the dynamics of incompressible two-phase viscous flows with surfactant. The resulting system of partial differential equations consists of a sixth-order Cahn-Hilliard equation for the…
In the present contribution we study the sliding mode control (SMC) problem for a diffuse interface tumor growth model coupling a viscous Cahn-Hilliard type equation for the phase variable with a reaction-diffusion equation for the…
The well-posedness of a system of partial differential equations and dynamic boundary conditions, both of Cahn-Hilliard type, is discussed. The existence of a weak solution and its continuous dependence on the data are proved using a…
A distributed optimal control problem for a diffuse interface model, which physical context is that of tumour growth dynamics, is addressed. The system we deal with comprises a Cahn--Hilliard equation for the tumour fraction coupled with a…
When plated onto substrates, cell morphology and even stem cell differentiation are influenced by the stiffness of their environment. Stiffer substrates give strongly spread (eventually polarized) cells with strong focal adhesions, and…
A typical phase field approach for describing phase separation and coarsening phenomena in alloys is the Cahn-Hilliard model. This model has been generalized to the so-called Cahn-Larch\'e system by combining it with elasticity to capture…
We derive a novel thermodynamically consistent Navier--Stokes--Cahn--Hilliard system with dynamic boundary conditions. This model describes the motion of viscous incompressible binary fluids with different densities. In contrast to previous…
We rigorously prove the convergence of weak solutions to a model for lipid raft formation in cell membranes which was recently proposed by Garcke et al. to weak (varifold) solutions of the corresponding sharp-interface problem for a…
We study the spreading and leveling of a gravity current in a Hele-Shaw cell with flow-wise width variations as an analog for flow {in fractures and horizontally heterogeneous aquifers}. Using phase-plane analysis, we obtain second-kind…
Cell-cell adhesion plays a vital role in the development and maintenance of multicellular organisms. One of its functions is regulation of cell migration, such as occurs, e.g. during embryogenesis or in cancer. In this work, we develop a…
Over the past decades, nonlocal models have been widely used to describe aggregation phenomena in biology, physics, engineering, and the social sciences. These are often derived as mean-field limits of attraction-repulsion agent-based…
We propose a simple mathematical model to describe the mechanical relaxation of cells within a curved epithelial tissue layer represented by an arbitrary curve in two-dimensional space. This model generalises previous one-dimensional models…