医学物理
Objectives- Several ultrasound measures have shown promise for assessment of steatosis compared to traditional B-scan, however clinicians may be required to integrate information across the parameters. Here, we propose an integrated…
The presented multi-scale, closed-loop blood circulation model includes arterial, venous, and portal venous systems, heart-pulmonary circulation, and micro-circulation in capillaries. One-dimensional models simulate large blood vessel flow,…
$\textbf{Purpose:}$ To assess the viability of a physics-based, deterministic and adjoint-capable algorithm for performing treatment planning system independent dose calculations and for computing dosimetric differences caused by anatomical…
This study proposes a versatile and efficient optimisation method for discrete coils that induce a magnetic field by their steady currents. The prime target is gradient coils for MRI (Magnetic Resonance Imaging). The derivative (gradient)…
Photoacoustic tomography (PAT) is a rapidly-evolving medical imaging modality that combines optical absorption contrast with ultrasound imaging depth. One challenge in PAT is image reconstruction with inadequate acoustic signals due to…
The integral quality monitor (IQM) system compares the signal measured with a large volume chamber mounted to the linear accelerator's head to the signal calculated using the patient DICOM RT plan for patient-specific quality assurance…
A software system named AutoMRISimQA was developed to monitor the daily performance of a wide-bore 3T scanner(MRI) which was designed and dedicated to radiotherapy simulation. The system can monitor the performance of the MRI simulator not…
Proprioception is crucial in intuitive control of prosthetic limbs and therefor contributes to intuitive prosthetic use. The agonist-antagonist myoneural interface (AMI) is an prosthetic innovation with enhanced control, reduced pain, and…
Proton magnetic resonance spectroscopic imaging (1H-MRSI) is a powerful tool that enables the multidimensional non-invasive mapping of the neurochemical profile at high-resolution over the entire brain. The constant demand for higher…
Objective: Conventional event positioning algorithms in light-sharing PET detectors are often limited by edge effects and the impact of inter-crystal scattering (ICS). This study explores the feasibility of deep neural network (DNN)…
The inherent characteristics of lung tissues, which are independent of breathing manoeuvre, may provide fundamental information on lung function. This paper attempted to study function-correlated lung textures and their spatial distribution…
Myocardial perfusion imaging using single-photon emission computed tomography (SPECT), or myocardial perfusion SPECT (MPS) is a widely used clinical imaging modality for the diagnosis of coronary artery disease. Current clinical protocols…
Photon counting detectors (PCDs) bring valuable advantages to diagnostic computed tomography (CT), including lower noise and higher resolution than energy integrating detectors. However, there are still several nonideal factors preventing…
The Electrocardiography Brain Perfusion index (EBPi) is a novel electrocardiography (ECG)-based metric that may function as a proxy for cerebral blood flow (CBF). We investigated the spatio-temporal correlation between EBPi and epileptic…
This study assessed the safety, feasibility, and acceptability of a novel device to monitor ischaemic stroke patients. The device captured electroencephalography (EEG) and electrocardiography (ECG) data to compute an ECG-based metric termed…
SPECT can enable the quantification of activity uptake in lesions and at-risk organs in {\alpha}-particle-emitting radiopharmaceutical therapies ({\alpha}-RPTs). But this quantification is challenged by the low photon counts, complicated…
The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…
Objective evaluation of quantitative imaging (QI) methods with patient data, while important, is typically hindered by the lack of gold standards. To address this challenge, no-gold-standard evaluation (NGSE) techniques have been proposed.…
Image-guided navigation of catheter devices to anatomic targets within large 3D cardiac chambers and vessels is challenging in the interventional setting due to the limitations of a conventional 2D x-ray projection format. Scanning-beam…
Even for short protocols (<1 min), head movement can compromise accurate haemodynamic modelling of cerebral CT perfusion (CTP) imaging in acute stroke. Frame-to-frame registration is the most common form of retrospective correction but…