医学物理
Accurate catheter digitization in CT-guided interstitial brachytherapy is a critical but time-consuming task, especially for complex implant configurations. We developed a data-efficient, physics-guided framework for automated…
The generalized equivalent uniform dose (gEUD) provides a biologically interpretable measure of heterogeneous dose distributions and is widely used in radiobiological modeling. However, because gEUD depends solely on dose magnitude, it does…
Purpose: Fully optical receive coils can potentially allow dense receiver arrays with a large channel count, reduced channel crosstalk, and less cable clutter. The power requirements of conventional low-noise amplifiers (LNAs) are…
Cardiac amyloidosis (CA) is increasingly recognized but remains substantially underdiagnosed, because its clinical and imaging phenotype overlaps with more common cardiomyopathies. Definitive subtype assignment and management further…
Purpose: Motion compromises the utility of high-resolution 3D MRI, an established tool in quantitative neuroimaging research. Deep learning-based methods have shown promise for mitigating motion-induced artifacts, but their development…
Surface relaxivity and time-dependent diffusion are two readouts of the same wall collisions on one substrate: the transverse rate that microstructure imaging fits is a bulk rate plus a surface rate $\rho\,(S/V)$, and intra- and…
Computational modeling and simulation are powerful tools for the assessment of medical device performance and safety, particularly for in silico clinical trials for automated medical systems. In ventilation, where managing gas exchange,…
In the USA, periodontal diseases, a spectrum of inflammatory conditions, affect 4 out of 10 adults (>=30 years). Current standards of care in clinical assessment of these diseases are invasive, subjective, only semi-quantitative, and…
This study compares the efficiency of three-dimensional deterministic discrete-ordinates calculations and voxel-based Monte Carlo simulations of the dose distribution around a model 6702 125I seed in a homogeneous water phantom. The…
Patient-specific quality assurance (PSQA) in pencil beam scanning proton therapy (PBS-PT) is often treated as a purely technical verification task. This PTCOG Treatment Efficiency Subcommittee White Paper instead frames PSQA as a…
International migrants face well-documented barriers to healthcare access, yet the extent to which these barriers shape patterns of disease co-occurrence remains poorly understood. Drawing on a nationwide dataset of approximately 13 million…
We report the performance of low gain avalanche Silicon detectors (LGADs) for instantaneous electron and proton beam monitoring across dose rates ranging from conventional radiotherapy to the FLASH regime, benefiting from the fast response…
Accurate interpretation of diffusion magnetic resonance imaging (dMRI) signals in grey matter (GM) remains challenging due to the complex, heterogeneous, and densely packed cellular environment. Numerical phantoms provide a controlled…
Magnetic particle imaging (MPI) enables real-time, radiation-free tracking of magnetic nanoparticle-coated instruments, making it highly suitable for interventional procedures. This study proposes a harmonic-aware transformer framework that…
In this work, we extend the local correlation equation (LCE) framework of the 2D Radon transform to clinical computed tomography (CT) geometry and propose a set of geometry-consistent discretization schemes. Building upon the…
MRI is increasingly critical for patients with active implantable medical devices (AIMDs), yet access depends on safety labeling derived from computational heating predictions under ISO/TS 10974 Tier 3. Published assessments have relied…
Purpose: To evaluate the feasibility of an integrated, free-breathing workflow for automated 2D pulmonary relaxometry (T1, T2) at 0.55T. Methods: A 2D inversion recovery ultra-fast balanced steady-state free precession (IR-uf-bSSFP)…
The movement distribution, and volume of both chyme and gas in the colon, are important metrics to understand colonic function in health, disease, and the effects of treatments and different foodstuffs. Current methods available for…
Hematologic toxicity (HT) is a major dose-limiting complication of pelvic radiotherapy for cervical cancer. Although radiomic and dosiomic features improve HT prediction beyond dosimetric metrics, their performance is highly sensitive to…
Image-guided therapies, including radiotherapy, biopsy and deep brain stimulation, rely on real-time targeting of anatomical structures. However, in the presence of motion, imaging latencies create a temporal misalignment between observed…