医学物理
GRASP (Golden-angle RAdial Sparse Parallel) MRI has emerged as one of the most influential motion-robust dynamic MRI frameworks over the past decade. By combining continuous golden-angle radial sampling with compressed sensing and parallel…
Modern magnetic resonance imaging (MRI) relies on application-specific multi-channel receive coils to achieve high performance, but these coils are typically costly, rigid, and difficult to generalize across anatomies. Recent wireless,…
Artificial intelligence is increasingly integrated into radiotherapy workflows, yet such pipelines remain vulnerable to out-of-distribution image data that may introduce unexpected behavior in clinical tasks. Deep learning-based anomaly…
Purpose: MicroWave Ablation (MWA) modeling and simulation bear great potential for loco-regional treatment of liver tumors. However, accurately positioning the antenna according to a planned orientation/location is technically challenging.…
Purpose: The Unadjusted Langevin Algorithm (ULA) in combination with diffusion models can generate high quality MRI reconstructions with uncertainty estimation from highly undersampled k-space data. However, sampling methods such as…
Electromagnetic interference (EMI) is a significant challenge for low-field MRI systems operating without conventional Faraday-shielded rooms. Traditional EMI mitigation approaches include external shields, subject grounding via electrodes,…
Purpose: Phase singularities are a common problem in image reconstruction with auto-calibrated sensitivities due to an inherent ambiguity of the estimation problem. The purpose of this work is to develop a method for detecting and…
Background: Access to radiotherapy (RT) is constrained by two compounding factors: insufficient machine capacity to meet patient demand and geographic distance from treatment facilities. Existing analyses address these factors separately,…
We developed a new magnetic resonance imaging method called multinuclear fingerprinting (MNF) which leverages simultaneously-acquired proton (1H) and sodium (23Na) data to generate seven quantitative maps of the whole brain: proton density…
Artificial intelligence (AI) empowers innovative diagnostic tools for common diseases, yet its clinical application in skeletal health evaluation is constrained by unsatisfactory accuracy, owing to the inherent porous and poroelastic…
Advanced radiotherapy approaches such as FLASH irradiation and spatially fractionated radiotherapy (SFRT) show potential to improve the therapeutic ratio, yet their biological mechanisms and optimal delivery parameters remain uncertain.…
Head impacts can cause concussion, but the precise biomechanical conditions that produce injury remain uncertain. Rotational acceleration has long been posited as the primary cause and has guided concussion prevention strategies. Using…
Accurate cardiac output (CO) estimation from photoplethysmography (PPG) is promising for unobtrusive hemodynamic monitoring, but remains difficult since CO is jointly determined by cardiac function and vascular tone. Conventional…
Background: Despite the large variety of materials used to repair congenital diaphragmatic hernia (CDH), none has proven ideal due to complications and risk of recurrence. Understanding the mechanical behavior of the diaphragm's central…
Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…
We present the first nuclear-scale persistent homology and Random Forest classification analysis of radiation-induced DNA double-strand break (DSB) topology across the clinical particle therapy range. Using TOPAS-nBio and the Voxel-Aware…
This work proposes Attractor-Vascular Coupling Theory (AVCT), a mathematical framework showing that cardiac attractor geometry encodes blood pressure (BP) information sufficient for AAMI-standard estimation, and validates the theory through…
Purpose: Stereotactic arrhythmia radioablation (STAR) is a non-invasive salvage therapy for refractory ventricular tachycardia (VT), especially in patients ineligible for catheter ablation. This narrative review and pooled analysis…
Positronium-based imaging requires realistic modelling of positronium (Ps) decay in matter. We introduce a modular Ps decay model implemented in GATE 9.4 and GATE 10, enabling the definition of an arbitrary number of decay channels…
Objective. Hypoxic tumor subvolumes resist radiation through elevated oxygen enhancement ratios (OER), yet no computational OER model is simultaneously particle-specific, mechanistically grounded, and fast enough for voxel-scale treatment…