医学物理

X-ray dark-field imaging is well-suited to visualizing the health of the lungs because the alveoli create a strong dark-field signal. However, time-resolved and tomographic (i.e., 4D) dark-field imaging is challenging, since most x-ray…

Spatiotemporal magnetic field variations from B0-inhomogeneity and diffusion-encoding-induced eddy-currents can be detrimental to rapid image-encoding schemes such as spiral, EPI and 3D-cones, resulting in undesirable image artifacts. In…

In intracranial aneurysm (IA) treatment, digital subtraction angiography (DSA) monitors device-induced hemodynamic changes. Quantitative angiography (QA) provides more precise assessments but is limited by hand-injection variability. This…

This paper analyzes conventional and deep learning methods for eliminating electromagnetic interference (EMI) in MRI systems. We compare traditional analytical and adaptive techniques with advanced deep learning approaches. Key strengths…

Small-animal diffusion MRI (dMRI) has been used for methodological development and validation, characterizing the biological basis of diffusion phenomena, and comparative anatomy. The steps from animal setup and monitoring, to acquisition,…

This study evaluates a multimodal machine learning framework for predicting treatment outcomes in intracranial aneurysms (IAs). Combining angiographic parametric imaging (API), patient biomarkers, and disease morphology, the framework aims…

Significance: Smartphones hold great potential in point-of-care settings due to their accessibility and computational capabilities. This is critical as clinicians increasingly seek to quantify skin-tone, a characteristic which has been…

This study leverages convolutional neural networks to enhance the temporal resolution of 3D angiography in intracranial aneurysms focusing on the reconstruction of volumetric contrast data from sparse and limited projections. Three…

The goal of this work is to study occurrences of non-unique solutions in dual-energy CT (DECT) for objects containing water and a contrast agent. Previous studies of the Jacobian of nonlinear systems identified that a vanishing Jacobian…

The design of nuclear imaging scanners is crucial for optimizing detection and imaging processes. While advancements have been made in simplistic, symmetrical modalities, current research is progressing towards more intricate structures,…

Introduction Speech is an integral component of human communication, requiring the coordinated efforts of various organs to produce sound (Titze & Alipour, 2006). The glottis region, a key player in voice production, assumes a crucial role…

Background: Advances in artificial intelligence, particularly large language models (LLMs), have the potential to enhance technical expertise in magnetic resonance imaging (MRI), regardless of operator skill or geographic location. Methods:…

We report on the first experimental characterization of a laser-wakefield accelerator able to deliver, in a single pulse, doses in excess of \unit[1]{Gy} on timescales of the order of a hundred femtoseconds, reaching unprecedented average…

Background & Purpose: FLASH or ultra-high dose rate (UHDR) radiation therapy (RT) has gained attention in recent years for its ability to spare normal tissues relative to conventional dose rate (CDR) RT in various preclinical trials.…

X-ray computed tomography (CT) in PET/CT is commonly operated with a single energy, resulting in a limitation of lacking tissue composition information. Dual-energy (DE) spectral CT enables material decomposition by using two different…

The heart is the central part of the cardiovascular network. Its role is to pump blood to various body organs. Many cardiovascular diseases occur due to an abnormal functioning of the heart. A diseased heart leads to severe complications…

This study aims to mitigate these biases and enhance QA analysis by applying a path-length correction (PLC) correction, followed by singular value decomposition (SVD)-based deconvolution, to angiograms obtained through both in-silico and…

In Angiographic Parametric Imaging (API), accurate estimation of parameters from Time Density Curves (TDC) is crucial. However, these estimations are often marred by errors arising from factors such as patient motion, procedural…

During intracranial aneurysm (IA) treatment with Diverters (FDs), the device/parent artery diameters ratio may influence the ability of the device to induce aneurysm healing response. Oversized FDs are safer to deploy but may not induce…

FLASH radiotherapy (FLASH-RT) is a new modality of radiotherapy by delivering doses with ultra-high dose rates. FLASH-RT has the ability to suppress tumor growth while sparing normal tissues, known as the FLASH effect. Although FLASH effect…