医学物理
MATI (Microstructural Analysis Toolbox for Imaging) is a versatile MATLAB-based toolbox that combines both simulation and data fitting capabilities for microstructural dMRI research. It provides a user-friendly, GUI-driven interface that…
The K\"arger model and its derivatives have been widely used to incorporate transcytolemmal water exchange rate, an essential characteristic of living cells, into analyses of diffusion MRI (dMRI) signals from tissues. The K\"arger model…
Statement of problem. Cold rolling is widely used for screw thread manufacturing in industry but is less common in implant dentistry, where cutting is the preferred manufacturing method. Purpose. The purpose of this in vitro study was to…
Intraoperative 2D quantitative angiography (QA) for intracranial aneurysms (IAs) has accuracy challenges due to the variability of hand injections. Despite the success of singular value decomposition (SVD) algorithms in reducing biases in…
Stretchable electronics capable of conforming to nonplanar and dynamic human body surfaces are central for creating implantable and on-skin devices for high-fidelity monitoring of diverse physiological signals. While various strategies have…
Infrared (IR) dyes, especially those within the near-infrared (NIR) spectrum, offer substantial advantages for in vivo imaging, owing to their deep tissue penetration and minimal background autofluorescence. Nanoparticles incorporating…
Permanent magnet array (PMA) is a popular option to provide the main magnetic field in a dedicated portable magnetic resonance imaging (MRI) system because it does not need power or a cooling system and has a much stronger field strength…
Biophysical modeling, particularly involving partial differential equations (PDEs), offers significant potential for tailoring disease treatment protocols to individual patients. However, the inverse problem-solving aspect of these models…
Purpose: With the development of spectral CT, several novel spectral filters have been introduced to modulate the spectra, such as split filters and spectral modulators. However, due to the finite size of the focal spot of X-ray source,…
This study investigates the noise characteristics of intraoperative X-ray fluoroscopic images acquired during real-time image-guided radiotherapy (IGRT), and presents a novel noise image generation method based on the identified noise…
We present a new imaging system to support real-time tumor tracking for surface-guided radiotherapy (SGRT). SGRT uses optical surface imaging (OSI) to acquire real-time surface topography images of the patient on the treatment couch.…
Receptor occupancy (RO) studies using PET neuroimaging play a critical role in the development of drugs targeting the central nervous system (CNS). The conventional approach to estimate drug receptor occupancy consists in estimation of…
Magnetoencephalography (MEG) allows the non-invasive detection of interictal epileptiform discharges (IEDs). Clinical MEG analysis in epileptic patients traditionally relies on the visual identification of IEDs, which is time consuming and…
Skin dose in radiotherapy is a key issue for reducing patient side effects, but dose calculations in this high-gradient region remains a challenge. To support radiation therapists and medical physicist in their decisions, a computational…
Previously, a synchrotron-based horizontal proton beamline (87.2 MeV) was successfully commissioned to deliver radiation doses in FLASH and conventional dose rate modes to small fields and volumes. In this study, we developed a strategy to…
Fatty acid can potentially serve as biomarker for evaluating metabolic disorder and inflammation condition, and quantifying the double bonds is the key for revealing fatty acid information. This study presents an assessment of a deep…
We present a novel approach for the reconstruction of time-resolved free-running first-pass myocardial perfusion MRI, named CMR-MOTUS. This method builds upon the MR-MOTUS framework and addresses the challenges of a contrast varying…
The paper considers an inverse problem of reconstructing the spatially distributed complex dielectric permittivity function using backscattered data of the electric field in the frequency domain. We develop iterative algorithm for…
The Dice Similarity Coefficient (DSC) is the current de facto standard to determine agreement between a reference segmentation and one generated by manual / auto-contouring approaches. This metric is useful for non-spatially important…
Transcranial ultrasound (TUS) has emerged as a promising tool in clinical and research settings due to its potential to modulate neuronal activity, open the blood-brain barrier, facilitate targeted drug delivery via nanoparticles, and…