医学物理
A spectral approach based on the Fourier diffraction theorem is combined with a pair of U-NETs to perform quantitative microwave imaging of an anthropomorphic breast phantom. The U-NET pair is trained on a spectral database constructed from…
Rotational symmetry is a defining feature of many tomography systems, including computed tomography (CT) and emission computed tomography (ECT), where detectors are arranged in a circular or periodically rotating configuration. This study…
Active breath-hold techniques effectively mitigate respiratory motion but pose challenges for patients who are ineligible for the procedure. Conventional treatment planning relies on multiple energy layers, extending delivery time due to…
Objective: To propose a CBCT dose optimization method using readily available measurement equipment in radiation oncology departments. Approach: A 0.6cc air kerma (Kair) calibrated Farmer chamber measured Kair at isocenter for five default…
In this paper, we proposed a method to optimize adaptive proton FLASH therapy (ADP FLASH) using modularized pin ridge filters (pRFs) by recycling module pins from the initial plan while reducing pRF adjustments in adaptive FLASH planning.…
High-aspect-ratio polymer materials are widely utilized in applications ranging from everyday materials such as clothing to specialized equipment in industrial and medical fields. Traditional fabrication methods, such as extrusion and…
This study introduces a novel framework for joint reconstruction of the activity and the attenuation (JRAA) in positron emission tomography (PET) using diffusion posterior sampling (DPS). By leveraging diffusion models (DMs), this approach…
The success of embolisation, a minimally invasive treatment of liver cancer, could be evaluated in the operational room with cone-beam CT by acquiring a dynamic perfusion scan. The reconstruction algorithm must address the issues of low…
Ultrasonography is a vital component of modern clinical care, with handheld probes routinely used for diagnostic imaging and procedural guidance. However, handheld ultrasound imaging is limited by factors such as the partial-cross-sectional…
In this work, we have investigated the sensitivity of the effectiveness (TCP) of molecular radiotherapy (MRT) treatment to uncertainties of the dose rate curves that may appear when reconstructing those curves. We generated different dose…
We demonstrated the feasibility of using bSSFP acquisitions for off-resonance insensitive high-resolution [6,6'-2H2]-glucose deuterium metabolic imaging (DMI) studies in the healthy human brain at 9.4T. Balanced SSFP acquisitions have…
Resolving arterial flows is essential for understanding cardiovascular pathologies, improving diagnosis, and monitoring patient condition. Ultrasound contrast imaging uses microbubbles to enhance the scattering of the blood pool, allowing…
Purpose: To investigate the impact of delivery techniques and planning parameters on interplay effect in lung SBRT. Methods: A dynamic virtual patient model containing normal structures and a tumor with adjustable sizes, locations, and 3D…
The average Relative Biological effectiveness (RBE) factors for neutron irradiation in the context of a BNCT treatment are studied. This research considers the various interactions and secondary particles of each process and estimates the…
Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their…
We present a multi-scale formalism that accounts for the formation of nano-scale bubbles/cavities owing to a burst of water molecules after the passage of high energy charged particles that leads to the formation of hot non-ionizing…
Blood-mimicking fluids (BMFs) play a critical role in ultrasonic imaging and Doppler flow studies by replicating the physical and acoustic properties of blood. This study introduces a novel soybean oil-in-water emulsion as a BMF with…
Current guidelines for elective nodal irradiation in oropharyngeal squamous cell carcinoma (OPSCC) recommend including large portions of the contralateral lymph system in the clinical target volume (CTV-N), even for lateralized tumors with…
The FLASH effect refers to a lower normal tissue damage for an equivalent tumour response, potentially widening the therapeutic window for radiotherapy. Although this effect has been demonstrated in various experiments using different types…
When treating moving tumors, the precise delivery of proton therapy by pencil beam scanning (PBS) is challenged by the interplay effect. Although several 4D-optimization methods have been proposed, what is the most beneficial motion…