医学物理
Modelling the diffusion-relaxation magnetic resonance (MR) signal obtained from multi-parametric sequences has recently gained immense interest in the community due to new techniques significantly reducing data acquisition time. A preferred…
Techniques for preclinical intensity modulated radiation therapy are being developed to improve translation by replicating the clinical paradigm. This study presents the first treatment planning comparison between small animal IMRT…
We investigate the effect of the microstructure on the mechanical response of lattice structures made of a defect tolerant Ti-14 Mo binary alloy fabricated by Electron Powder Bed Fusion. Some of the lattice structures were subjected to…
Magnetic resonance imaging and spectroscopy rely on the magnetic fields generated by radiofrequency volume coils to acquire high-quality data. Consequently, a comprehensive understanding of electromagnetic field behavior in RF volume coils…
Background: Despite the significant advances made in the field of computational fluid dynamics (CFD) to simulate the left atrium (LA) in atrial fibrillation (AF) conditions, the connection between atrial structure, flow dynamics, and blood…
Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting over 1% of the population. It is usually triggered by irregular electrical impulses that cause the atria to contract irregularly and…
Boron Neutron Capture Therapy (BNCT) is a form of radiotherapy based on the irradiation of the tumour with a low energy neutron beam, after the administration of a selective drug enriched in boron-10. The therapy exploits the high cross…
The treatment of intracranial aneurysms (IA) relies on angiography guidance using biplane views. However, accurate flow estimation and device sizing for treatment are often compromised by vessel overlap and foreshortening, which can obscure…
Osseointegration is crucial to the success of biomedical implants. Additive manufacturing of implants offers a high degree of design freedom, enabling precise control over implant geometry and material composition. Bioactive glass (BG) can…
Over the past years, rapid progress has been made on soft-matter electronics for wearable and implantable devices, for bioelectronics and optogenetics. Liquid Metal (LM) based electronics were especially popular, due to their long-term…
Premature delivery is a leading cause of fetal death and morbidity, making the prediction and treatment of preterm contractions critical. The electrohysterographic (EHG) signal measures the electrical activity controlling uterine…
This article presents a study on the influence of antenna parameters in medical microwave radiometers on brightness temperature. A series of computational experiments was conducted to analyse the dependence of brightness temperature on…
This study proposes a novel, contrast-free Magnetic Resonance Fingerprinting (MRF) method using balanced Steady-State Free Precession (bSSFP) sequences for the quantification of cerebral blood volume (CBV), vessel radius (R), and…
This work examines the hypothesis that intravoxel incoherent motion MRI (IVIM) can quantify local cerebral blood flow (qCBF), infarct volume, and define the ischemic penumbra for determination of the perfusion-diffusion mismatch (PWI/DWI)…
Dosimetry in BNCT poses significant challenges due to the indirect effect of neutrons interacting with elements within the body and uncertainties associated with the uptake of boron compounds used in clinical practice. Current treatment…
The presence of tumor hypoxia is known to correlate with poor patient prognosis. Measurement of tissue oxygen concentration can be challenging, but recent advancements using positron annihilation lifetime spectroscopy (PALS) in…
Intravoxel Incoherent Motion (IVIM) is a non-contrast magnetic resonance imaging diffusion-based scan that uses a multitude of b-values to measure various speeds of molecular perfusion and diffusion, sidestepping inaccuracy of arterial…
This study investigates the application of surface-enhanced Raman spectroscopy (SERS) as a diagnostic tool for myasthenia gravis, a severe neuromuscular disorder characterized by muscle weakness and fatigue. Blood serum samples were…
Purpose: Patient-specific ridge filters can modulate proton energy to obtain a conformal dose. We describe a new framework for optimization of filter design and spot maps to meet the unique demands of FLASH radiotherapy. We demonstrate an…
The high compliance of the urinary bladder during filling is essential for its proper function, enabling it to accommodate significant volumetric increases with minimal rise in transmural pressure. This study aimed to elucidate the physical…