医学物理
High blood pressure (hypertension) is the number one risk factor for premature death. Hypertension is asymptomatic, so blood pressure must be regularly monitored to diagnose it. In auscultatory blood pressure measurement, a patient's…
Multi-source stationary computed tomography (MSS-CT) offers significant advantages in medical and industrial applications due to its gantry-less scan architecture and/or capability of simultaneous multi-source emission. However, the lack of…
Total-Body PET is one of the most promising medical diagnostics modalities. The high sensitivity provided by Total-Body technology can be advantageous for novel tomography methods like positronium imaging. Several efforts are ongoing to…
Purpose: The XCAT phantom allows for highly sophisticated multimodality imaging research. It includes a complete set of organs, muscle, bone, soft tissue, while also accounting for age, sex, and body mass index (BMI), which allows phantom…
Medical imaging systems are commonly assessed and optimized by the use of objective measures of image quality (IQ). The performance of the ideal observer (IO) acting on imaging measurements has long been advocated as a figure-of-merit to…
Positron emission tomography (PET) is an important modality for diagnosing diseases such as cancer and Alzheimer's disease, capable of revealing the uptake of radiolabeled molecules that target specific pathological markers of the diseases.…
The key molecules such as triphosphate (ATP), glutathione (GSH), and homocarnosine (hCs) - central to metabolic processes in the human brain remain elusive or challenging to detect with upfield 1H-MRSI. Traditional 3D 1H-MRSI in vivo faces…
BACKGROUND: Radiomics provides quantitative features of pulmonary nodules (PNs) which could aid lung cancer diagnosis, but medical image acquisition variability is an obstacle to clinical application. Acquisition effects may differ between…
The development of tissue engineering structures (scaffolds) for the reconstruction of bone tissue defects is the relevant task of modern biomedical materials science. Compared to metal-based structures, polymer constructs provide numerous…
A model for the progression of dental caries is derived. The analysis starts at the microscopic reaction and diffusion process. The local equations are averaged to derive a set of macroscopic equations. The global system includes features…
In recent years, four-dimensional (4D) fabrication has emerged as a powerful technology capable of revolutionizing the field of tissue engineering. This technology represents a shift in perspective from traditional tissue engineering…
Convergence of the block iterative method in image reconstruction for positron emission tomography (PET) requires careful control of relaxation parameters, which is a challenging task. The automatic determination of relaxation parameters…
Purpose: To propose a B1+ mapping technique for imaging of body parts containing metal hardware, based on magnitude images acquired with turbo spin echo (TSE) pulse sequences. Theory and Methods: To encode the underlying B1+, multiple (two…
Scatter signals can degrade the contrast and resolution of computed tomography (CT) images and induce artifacts. How to effectively correct scatter signals in CT has always been a focal point of research for researchers. This work presents…
Purpose: Measuring the ortho-positronium (oPs) lifetime in human tissue bears the potential of adding clinically relevant information about the tissue microenvironment to conventional positron emission tomography (PET). Through phantom…
In image-guided radiotherapy (IGRT), four-dimensional cone-beam computed tomography (4D-CBCT) is critical for assessing tumor motion during a patients breathing cycle prior to beam delivery. However, generating 4D-CBCT images with…
Low-intensity Transcranial Ultrasonic Stimulation (TUS) is a non-invasive brain stimulation technique enabling cortical and deep brain targeting with unprecedented spatial accuracy. Given the high rate of adoption by new users with varying…
Line-by-line scanning with linear arrays is a standard image formation method in clinical ultrasound. This method examines progressively a given region of interest by conducting focused pulse-echo measurements with dynamic transmit and…
Thanks to the rapidly evolving integration of LLMs into decision-support tools, a significant transformation is happening across large-scale systems. Like other medical fields, the use of LLMs such as GPT-4 is gaining increasing interest in…
Purpose: To identify the predominant source of the $T_1$ variability described in the literature, which ranges from 0.6-1.1 s for brain white matter at 3 T. Methods: 25 $T_1$-mapping methods from the literature were simulated with a…