医学物理
We propose a novel approach using Multiplex-Coherent Anti-Stokes Raman Scattering (M-CARS) for la-bel-free discriminations in biomedical tissues. The strategy is based on the evaluation of the contrast be-tween resonant and nonresonant…
Focused ultrasound (FUS) therapy is a promising tool for optimally targeted treatment of spinal cord injuries (SCI), offering submillimeter precision to enhance blood flow at injury sites while minimizing impact on surrounding tissues.…
Lactate is crucial in the brain, as it is involved in neuronal activity and memory formation. This is thought to be related to the astrocyte-neuron lactate shuttle hypothesis (ANLS), which has been debated for 30 years, not least because it…
Purpose: To theoretically and experimentally study implant lead tip heating caused by radiofrequency (RF) power deposition in different wire configurations that contain loop(s). Methods: Maximum temperature rise caused by RF heating was…
Understanding alterations in structural disorders in tissue or cells or building blocks, such as DNA or chromatin in the human brain, at the nano to submicron level provides us with efficient biomarkers for Alzheimers detection. Here, we…
One of the goals of personalized medicine is to tailor diagnostics to individual patients. Diagnostics are performed in practice by measuring quantities, called biomarkers, that indicate the existence and progress of a disease. In common…
This study pioneers the two-field correlation spectroscopy (COSY) in zero to ultralow field (ZULF) liquid state NMR, employing hyperpolarized [1-$^{13}$C]pyruvate as a model system. We demonstrate the successful integration of signal…
Magnetic Detection Electrical Impedance Tomography is a novel technique that could enable non-invasive imaging of fast neural activity in the brain. However, commercial magnetometers are not suited to its technical requirements.…
We investigate the connection between visual semantic features defined in PI-RADS and associated risk factors, moving beyond abnormal imaging findings, establishing a shared framework between medical and AI professionals by creating a…
Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, its clinical implementations…
This study aims to validate if MRI can measure anisotropic mesoscopic Larmor frequency shifts from white matter axonal microstructure relative to the B0 direction and if dMRI can estimate this anisotropy. Recent models describe how…
Objective: The aim of this study is to validate the effectiveness of an energy-modulated scatter correction method in suppressing scatter in photon-counting detector (PCD)-based cone beam CT (CBCT) imaging. Approach: The scatter correction…
This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…
Three different computed tomography (CT) reconstruction algorithms: Filtered Back Projection (FBP), Unified Tomographic Reconstruction (UTR) and customized Simultaneous Algebraic Reconstruction Technique (cSART), have been systematically…
The first partial boundary data complex geometrical optics based methods for electrical impedance tomography in three dimensions are developed, and tested, on simulated and experimental data. The methods provide good localization of targets…
Palpation of human tissue during Minimally Invasive Surgery is hampered due to restricted access. In this extended abstract, we present a variable stiffness and dynamic force range sensor that has the potential to address this challenge.…
Computed Tomography (CT) has been widely adopted in medicine and it is increasingly being used in scientific and industrial applications. Parallelly, research in different mathematical areas concerning discrete inverse problems has led to…
The production of 225Ac using either a proton or electron accelerator requires a target of 226Ra. Radium metal is difficult to work with and so a radium salt, such as radium carbonate, is preferred as a target material. Normally available…
Seismocardiogram (SCG) signals can play a crucial role in remote cardiac monitoring, capturing important events such as aortic valve opening (AO) and mitral valve closure (MC). However, existing SCG methods for detecting AO and MC typically…
Seismocardiography (SCG) has gained significant attention due to its potential applications in monitoring cardiac health and diagnosing cardiovascular conditions. Conventional SCG methods rely on accelerometers attached to the chest, which…