医学物理
Nanodevices that show the potential for non-linear transformation of electrical signals and various forms of memory can be successfully used in new computational paradigms, such as neuromorphic or reservoir computing (RC). Dedicated…
Objective: Endobronchial Valves are a minimally invasive treatment for emphysema. After bronchoscopic placement the valves reduce the flow of air into targeted areas of the lung, causing collapse, and allowing the remainder of the lung to…
The mechanical properties of micro-scale bio-entities are fundamental for understanding their functions and pathological states. However, current methods for assessing elastic properties at single-particle level such as Brillouin and atomic…
Sequential registering of fluorescence signals in conventional Excitation-Emission Matrices (EEMs), followed by modeling based on multilinear properties of the data, requires stable fluorophore concentrations throughout the acquisition of…
This work reviews the concepts of an event used in micro- and nanodosimetry and analyzes how single event distributions could theoretically be derived from probability distributions related to interactions of the primary particle which…
Background: Lower production of H$_2$O$_2$ in water is a hallmark of ultra-high dose rate (UHDR) compared to the conventional dose rate (CDR). However, the current computational models based on the predicted yield of H$_2$O$_2$ are in…
Background: Real-time treatment planning in IMRT is challenging due to complex beam interactions. AI has improved automation, but existing models require large, high-quality datasets and lack universal applicability. Deep reinforcement…
Background: Multi-collimator proton minibeam radiation therapy (MC-pMBRT) has recently emerged as a versatile technique for dose shaping, enabling peak-valley dose patterns in organs-at-risk (OAR) while maintaining a uniform dose…
X-ray fluorescence computed tomography (XFCT), a form of X-ray molecular imaging, offers detailed quantitative imaging capabilities for high-Z metal nanoparticles (MNPs), which are widely studied for their applications in multifunctional…
Objective To conduct biomechanical analysis on the starting technique of male short-distance speed skating athletes in China and determine the key factors affecting the effectiveness of the starting movement. Methods 13 high-level male…
Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…
Multi-source static Computed Tomography (CT) systems have introduced novel opportunities for adaptive imaging techniques. This work presents an innovative method of fluence field modulation using spotlight collimators. These instruments…
Neurological Positron Emission Tomography (PET) is a critical imaging modality for diagnosing and studying neurodegenerative diseases like Alzheimer's disease. However, the inherent low spatial resolution of PET images poses significant…
Objectives: To determine the on-field validity of instrumented mouthguards (iMGs) in American football and to quantify head acceleration event (HAE) incidence in NCAA football players. Methods: Instrumented mouthguards were fitted to 35…
Musculoskeletal models are pivotal in the domains of rehabilitation and resistance training to analyze muscle conditions. However, individual variability in musculoskeletal parameters and the immeasurability of some internal biomechanical…
The progression of cancer is associated with different genetic and epigenetic events which result in nano to microscale structural alterations in cells/tissue. However, these structural alterations in the early stage of the disease remain…
Cardiac arrest is very common nowadays. Sudden heart attack is a condition where the heart suddenly stops beating causing a significant decrease in blood flow to the brain. The first step in medical point of view is for a patient…
Amyloidosis is a protein misfolding disease caused by the deposition of large, insoluble aggregates (amyloid fibrils) of protein in a tissue, which has been associated with various conditions, such as lymphoid disorders, Alzheimer's…
Limited-view computed tomography (CT) presents significant potential for reducing radiation exposure and expediting the scanning process. While deep learning (DL) methods have exhibited promising results in mitigating streaking artifacts…
Photoacoustic (PA) waves are strongly distorted and attenuated in skull bone. To study these effects on PA imaging, we designed and 3D-printed tissue-mimicking phantoms of human skull. We present a comparison of results in phantom and ex…