医学物理
Prostate cancer is a major global health concern, requiring advancements in robotic surgery and diagnostics to improve patient outcomes. A phantom is a specially designed object that simulates human tissues or organs. It can be used for…
Objective: To assess response-to-loading in a human cadaveric knee joint model under different loading conditions before and after meniscectomy Design: In this prospective study, stress magnetic resonance imaging was performed using an…
This study investigates the sensitivity and specificity of the MapCHECK phantom housed in MapPHAN to errors in conformal arc Stereotactic Ablative Body Radiotherapy (SABR). A specific focus is applied to Organ At Risk (OAR) dosimetry.…
Chronic pancreatitis (CP) is a progressive inflammatory disease frequently associated with severe, treatment-resistant abdominal pain, which is hypothesized to result from pancreatic ductal hypertension (PDH) secondary to ductal strictures…
Objective: The aim of this study was to evaluate the efficacy of alendronate therapy in improving bone density distribution in skull bones and corresponding ultrasound permeability in patients who had previously experienced unsuccessful…
To navigate medical instruments safely and accurately inside a patient's vascular tree, combining X-ray fluoroscopy with intermittent contrast injections is the gold standard. However, prolonged exposure to ionizing radiation poses health…
Background: Upright proton therapy with compact delivery systems has the potential to reduce costs for treatments but could also lead to broadening of the beam penumbra due to energy selection close to the patient. Purpose: This study aims…
Wireless radio frequency coils provide a promising solution for clinical MR applications due to several benefits, such as cable-free connection and compatibility with MR platforms of different vendors. Namely, for the purpose of clinical…
Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…
This study presents the design, simulation, and experimental validation of a novel multimodal concentric surface coil for MR imaging, developed to achieve higher B1 field efficiency while maintaining low SAR for enhanced imaging…
Objective: This study aims to uncover the opaque decision-making process of an artificial intelligence (AI) agent for automatic treatment planning. Approach: We examined a previously developed AI agent based on the Actor-Critic with…
In this study, various nanoparticle species-including Au and Gd$_2$O$_3$-were irradiated with low-energy gamma rays, such as 59.5 keV photons from $^{241}$Am. Pulse-height spectra were recorded using a liquid-scintillation counting system…
Accurate patient positioning is critical for precise radiotherapy dose delivery, as positioning errors can significantly affect treatment outcomes. This study introduces a novel method for tracking loco-regional tissue deformation through…
Sodium magnetic resonance imaging (MRI) is sensitive and specific to ionic balance of cells owing to 10 fold difference in sodium concentration across membrane actively maintained by sodium potassium (Na+ K+) pump. Disruption of the pump…
Near infrared spectroscopy (NIRS) is an optical technique that is widely used to monitor tissue oxygenation. These devices take advantage of the near infrared light to monitor deep tissues like brain, muscle or placenta. In this study, we…
Depth electrodes used in stereoelectroencephalography (sEEG) and deep-brain stimulation (DBS) are essential tools for neural recording and stimulation. Traditional designs have limited spatial resolution, typically 8 to 16 cylindrical…
Temperature-responsive polymeric micelles have great potential in drug delivery, enhancing therapeutic efficacy while minimizing systemic toxicity. This study investigates the self-assembly of poly(ethylene…
Background: Computational fluid dynamics (CFD) has become an essential design tool for ventricular assist devices (VADs), where the goal of maximizing performance often conflicts with biocompatibility. This tradeoff becomes even more…
Interoperative measurements using magnetic sensors is a valuable technique in cancer surgery for finding magnetic tracers. Here we present a fiber-coupled nitrogen-vacancy (N-V) center magnetometer capable of detecting iron oxide suspension…
Image reconstruction in Magnetic Resonance Imaging (MRI) is fundamentally a linear inverse problem, such that the image can be recovered via explicit pseudoinversion of the encoding matrix by solving $\textbf{data} = \textbf{Encode} \times…