医学物理
Background: In MR-guided proton therapy planning, aligning MR and CT images is key for MR-based CT synthesis, especially in mobile regions like the head-and-neck. Misalignments here can lead to less accurate synthetic CT (sCT) images,…
Minimally invasive interventions performed inside brain vessels with the synergistic use of microcatheters pushed over guidewires have revolutionized the way aneurysms, stroke, arteriovenous malformations, brain tumors and other…
Proton arc therapy (PAT) is an emerging and promising modality in radiotherapy, offering improved dose distribution and treatment robustness over intensity-modulated proton therapy. Yet, identifying the optimal energy layer (EL) sequence…
Intensity modulated proton therapy (IMPT) is an advanced cancer treatment modality that offers significant advantages over conventional X-ray therapies, particularly in its ability to minimize radiation dose beyond the tumor target. This…
Modern MRI relies on the well-established Echo-Planar-Imaging (EPI) method for fast acquisition. EPI is the workhorse of diffusion and functional MRI in neuroscience as well as of many dynamic applications for clinical body imaging. Its…
Introduction: Rehabilitation after a neurological impairment can be supported by functional electrical stimulation (FES). However, FES is limited by early muscle fatigue, slowing down the recovery progress. The use of optimal control to…
Controlling the size of powder particles is pivotal in the design of many pharmaceutical forms and the related manufacturing processes and plants. One of the most common techniques for particle size reduction in process industry is powder…
Purpose: Radiation pneumonitis (RP) is a serious complication of intensity-modulated radiation therapy (IMRT) for breast cancer patients, underscoring the need for precise and explainable predictive models. This study presents an…
Space radiation poses a significant challenge for long duration human space missions, with sources including Galactic Cosmic Rays, Solar Particle Events, and trapped particles in the Van Allen belts. These high-energy radiations cause…
Background: Intravoxel Incoherent Motion (IVIM) model characterizes both water diffusion and perfusion in tissues, providing quantitative biomarkers valuable for tumor tissue characterization. However, parameter estimation based on this…
Ultrasound simulations used for treatment planning in transcranial ultrasound stimulation(TUS) currently depend on converting computed tomography(CT) images to acoustic properties. Aiming to reduce subject exposure to ionising radiation,…
Purpose: To develop a self-supervised scan-specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods: We propose REFINE-MORE (REference-Free Implicit NEural representation with MOdel…
Background: Adnexal masses are heterogeneous and have varied sonographic presentations, making them difficult to diagnose correctly. Purpose: Our study aimed to develop an innovative hybrid artificial intelligence/computer aided diagnosis…
Purpose: To develop and evaluate a new pulse sequence for highly accelerated distortion-free diffusion MRI (dMRI) by inserting additional echoes without prolonging TR, when generalized slice dithered enhanced resolution (gSlider)…
The future of ART in head and neck cancer is just beginning. Novel technologies have pushed the boundary of what is possible in terms of techniques to identify biomarkers for adaptation as well as innovative devices specialized to respond…
Anchor point placement is a crucial yet often overlooked aspect of exosuit design since it determines how forces interact with the human body. This work analyzes the impact of different anchor point positions on gait kinematics, muscular…
Biocompatibility is a critical factor in the application of nanomaterials in medical fields, as these materials must interact safely and effectively with biological systems to be viable for therapeutic and diagnostic use. This article…
Glioblastoma, the most aggressive primary brain tumor, poses a severe clinical challenge due to its diffuse microscopic infiltration, which remains largely undetected on standard MRI. As a result, current radiotherapy planning employs a…
Background: Ultrasound imaging plays a pivotal role in diagnosing carotid atherosclerosis, a significant precursor to cardiovascular and cerebrovascular diseases and events. This non-invasive modality provides real-time, high-resolution…
Objectives: Magnetic resonance elastography (MRE) is a noninvasive technique for assessing the viscoelastic properties of soft biological tissues in vivo, with potential relevance for pediatric tumor evaluation. This study aimed to evaluate…