医学物理
The kernel reconstruction is a method that reduces noise in dynamic positron emission tomography (PET) by exploiting spatial correlations in the PET image. Although this method works well for large anatomical regions with relatively slow…
In positron emission tomography (PET), time-of-flight (TOF) information localizes source positions along lines of response. Cherenkov-radiator-integrated microchannel-plate photomultiplier tubes have achieved 30 ps TOF resolution,…
Purpose: Examine the theory and potential clinical application of estimated intravoxel flow of separated perfusion, tubular flow, and diffusion from multi-b-value DWI in kidney allografts. Methods: Multi-b-value DWI (9 b-values; 0-800…
Multi-layer diffuse correlation spectroscopy (DCS) models have been developed to reduce the contamination of superficial signals in cerebral blood flow index (CBFi) measurements. However, a systematic comparison of these models and clear…
Purpose: This study explores the feasibility of dose-escalated proton beam therapy (dPBT) for Locally Advanced Pancreatic Cancer (LAPC) patients by modeling common patient scenarios using current clinically-adopted practices. Methods: Five…
Wound geometry and the mechanical properties of human skin govern the failure modes of partially healed or scarred tissue. Though dermatologists and surgeons develop an intuitive understanding of the mechanical characteristics of skin…
Magnetic resonance imaging (MRI) scanners have advanced significantly, with a growing use of highfield 3 T systems. This evolution gives rise to safety concerns for healthcare personnel working in proximity to MRI equipment. While…
This study presents a practical and dose-efficient strategy for resolution enhancement in planar radiography, based on mechanically supersampled acquisition with high-Z photon-counting detectors (PCDs). Unlike prior event-based or cluster…
This paper presents an improved technique for solving the inverse problem in magnetic induction tomography (MIT) by considering skin and proximity effects in coils. MIT is a non-contact, noninvasive, and low-cost imaging modality for…
Assessment of muscle coordination during cycling may provide insight into motor control strategies and movement efficiency. This study evaluated muscle synergies and coactivation patterns as indicators of neuromuscular coordination in…
To simultaneously fit multiple-pool effects, spectrally selective 3D CEST imaging typically requires single-shot readouts to save time. However, to date, FLASH and EPI have been the primary pulse sequences used for this purpose. They suffer…
The open-source console MaRCoS, which stands for "Magnetic Resonance Control System", combines hardware, firmware and software elements for integral control of Magnetic Resonance Imaging (MRI) scanners. Previous developments have focused on…
Time-resolved CBCT imaging, which reconstructs a dynamic sequence of CBCTs reflecting intra-scan motion (one CBCT per x-ray projection without phase sorting or binning), is highly desired for regular and irregular motion characterization,…
This report details the successful construction of an ultrasound imaging platform and the design and fabrication of a novel ultrasound endoscope probe. The projects primary objective was to establish a functional system for acquiring and…
Purpose: This work aims to develop a robust Nyquist ghost correction method for multishot echo-planar imaging (EPI). The method helps correct challenging Nyquist ghosts, particularly on scanners with high-performance gradients or ultra-high…
By integrating the generative strengths of diffusion models with the representation capabilities of frequency-domain attention, DFAM effectively enhances reconstruction performance under low-SNR condi-tions. Experimental results demonstrate…
This study is to evaluate the impact of lung volume choices on predicting radiation pneumonitis (RP) risk in patients with locally advanced NSCLC undergoing radiotherapy. Dosimetric variables V20, V5, and mean lung dose (MLD) were extracted…
Butterfly tumors are a distinct class of gliomas that span the corpus callosum, producing a characteristic butterfly-shaped appearance on MRI. The distinctive growth pattern of these tumors highlights how white matter fibers and structural…
The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostatic lesion (DIL) boost represents a significant advancement in…
Purpose: Accurate segmentation of glioma subregions in multi-parametric MRI (MP-MRI) is essential for diagnosis and treatment planning but remains challenging due to tumor heterogeneity and ambiguous boundaries. This study proposes an…