医学物理
Accurate targeting is critical for the effectiveness of transcranial focused ultrasound (tFUS) neuromodulation. While CT provides accurate skull acoustic properties, its ionizing radiation and poor soft tissue contrast limit clinical…
Ultrasound imaging of the cortex of long bones may enable the measurement of the cortical thickness and the ultrasound wave speed in cortical bone tissue. However, with bone loss, the cortical porosity and the size of the pores increase,…
The aim of the present article is to enrich the comprehension of iterative magnetic resonance imaging (MRI) reconstructions, including compressed sensing (CS) and iterative deep learning (DL) reconstructions, by describing them in the…
Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-invasive option for such patients. While photon-based STAR has…
Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…
Purpose. Portable low-field (< 0.1 T) MRI is increasingly used for point-of-care imaging, but electromagnetic interference (EMI) presents a significant challenge, especially in unshielded environments. EMI can degrade image quality and…
Simulated data is increasingly valued by researchers for validating MRS processing and analysis algorithms. However, there is no consensus on the optimal approaches for simulation models and parameters. This study introduces a novel MRS…
Cardiovascular magnetic resonance imaging is a powerful diagnostic tool for assessing cardiac structure and function. However, traditional breath-held imaging protocols pose challenges for patients with arrhythmias or limited breath-holding…
In the context of numerical simulations of the vascular system, local geometric uncertainties have not yet been examined in sufficient detail due to model complexity and the associated large numerical effort. Such uncertainties are related…
Zero echo time (ZTE) sequences have proven a powerful tool for Magnetic Resonance Imaging (MRI) of ultrashort T2 tissues, but they fail to produce useful images in the presence of strong field inhomogeneities. Here we present a method to…
Objective. To develop methods to design the complete magnetic system for a truly portable MRI scanner for neurological and musculoskeletal (MSK) applications, optimized for field homogeneity, field of view (FoV) and gradient performance…
This literature review presents a comprehensive overview of machine learning (ML) applications in proton magnetic resonance spectroscopy (MRS). As the use of ML techniques in MRS continues to grow, this review aims to provide the MRS…
Historically, functional magnetic resonance imaging (fMRI) of the brain has focused primarily on gray matter, particularly the cortical gray matter and associated nuclei. However, recent work has demonstrated that functional activity in…
Microdosimetry investigates the energy deposition of ionizing radiation at microscopic scales, beyond the assessment capabilities of macroscopic dosimetry. This contributes to an understanding of the biological response in radiobiology,…
Background: Trans-spinal FUS (tsFUS) has recently been shown promise in modulating spinal reflexes in rodents, opening new avenues for spinal cord interventions in motor control and pain management. However, anatomical differences between…
Purpose: This work aims to enable real-time automated intra-uterine volumetric reporting and fetal weight estimation for fetal MRI, deployed directly on the scanner. Methods: A multi-region segmentation nnUNet was trained on 146 bSSFP…
We set up a mathematical model for a DC current in a human tissue that shows an attenuation effect in an extended circuit. We give a positive lower bound on the time duration over which this is guaranteed to happen in terms of the…
Accurate MR signal simulation, including microvascular structures and water diffusion, is crucial for MRI techniques like fMRI BOLD modeling and MR vascular Fingerprinting (MRF), which use susceptibility effects on MR signals for tissue…
Current approaches to in vivo imaging of the mouse central nervous system (CNS) do not offer a combination of micrometer resolution and a whole-brain field of view. To address this limitation, we introduce an approach based on synchrotron…
In the first part of this paper, quantitative aspects of propagation-based phase-contrast imaging (PBI) were investigated using theoretical and numerical approaches, as well as experimental two-dimensional PBI images collected with plane…