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相关论文: Coalescence in a random background

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We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

种群与进化 · 定量生物学 2018-07-19 George W. A. Constable , Alan J. McKane

This paper studies the spatial coalescent on $\Z^2$. In our setting, the partition elements are located at the sites of $\Z^2$ and undergo local delayed coalescence and migration. That is, pairs of partition elements located at the same…

概率论 · 数学 2009-10-07 Andreas Greven , Vlada Limic , Anita Winter

We consider a model of a population of fixed size $N$ undergoing selection. Each individual acquires beneficial mutations at rate $\mu_N$, and each beneficial mutation increases the individual's fitness by $s_N$. Each individual dies at…

概率论 · 数学 2015-07-03 Jason Schweinsberg

Duality plays an important role in population genetics. It can relate results from forwards-in-time models of allele frequency evolution with those of backwards-in-time genealogical models; a well known example is the duality between the…

种群与进化 · 定量生物学 2019-08-09 Robert C. Griffiths , Paul A. Jenkins , Sabin Lessard

When a beneficial mutation occurs in a population, the new, favored allele may spread to the entire population. This process is known as a selective sweep. Suppose we sample $n$ individuals at the end of a selective sweep. If we focus on a…

概率论 · 数学 2007-05-23 Jason Schweinsberg , Rick Durrett

Two major sources of stochasticity in the dynamics of neutral alleles result from resampling of finite populations (genetic drift) and the random genetic background of nearby selected alleles on which the neutral alleles are found (linked…

种群与进化 · 定量生物学 2013-01-15 Graham Coop , Peter Ralph

We begin by reviewing some probabilistic results about the Dirichlet Process and its close relatives, focussing on their implications for statistical modelling and analysis. We then introduce a class of simple mixture models in which…

统计方法学 · 统计学 2010-03-23 Peter J. Green

When biological populations expand into new territory, the evolutionary outcomes can be strongly influenced by genetic drift, the random fluctuations in allele frequencies. Meanwhile, spatial variability in the environment can also…

种群与进化 · 定量生物学 2024-06-27 Jimmy Gonzalez Nuñez , Jayson Paulose , Wolfram Möbius , Daniel A. Beller

Consider a genetic locus carrying a strongly beneficial allele which has recently fixed in a large population. As strongly beneficial alleles fix quickly, sequence diversity at partially linked neutral loci is reduced. This phenomenon is…

种群与进化 · 定量生物学 2007-05-23 P. Pfaffelhuber , A. Studeny

We consider the range $R^{(n)}$, the tree made up of visited vertices by a diffusive null-recurrent randomly biased walk $\mathbb{X}$ on a Galton-Watson tree $\mathbb{T}$ up to the $n$-th return time to its root and we consider the…

概率论 · 数学 2024-10-29 Alexis Kagan

We develop a diffusion approximation for systems subject to fast random resetting by small amplitudes. Equivalently, this describes systems with frequent but small catastrophes. We demonstrate the validity of the approximation by computing…

统计力学 · 物理学 2026-02-26 Tobias Galla

The problem of natural selection in dispersal-structured populations consisting of individuals characterized by different diffusion coefficients is studied. The competition between the organisms is taken into account through the assumption…

适应与自组织系统 · 物理学 2020-05-01 E. Heinsalu , D. Navidad Maeso , M. Patriarca

We extend the spatial $\Lambda$-Fleming-Viot process introduced in [Electron. J. Probab. 15 (2010) 162-216] to incorporate recombination. The process models allele frequencies in a population which is distributed over the two-dimensional…

概率论 · 数学 2012-11-28 A. M. Etheridge , A. Véber

We suggest a simple deterministic approximation for the growth of the favoured-allele frequency during a selective sweep. Using this approximation we introduce an accurate model for genetic hitch-hiking. Only when Ns < 10 (N is the…

种群与进化 · 定量生物学 2025-10-01 A. Eriksson , P. Fernstrom , B. Mehlig , S. Sagitov

From the exact single step evolution equation of the two-point correlation function of a particle distribution subjected to a stochastic displacement field $\bu(\bx)$, we derive different dynamical regimes when $\bu(\bx)$ is iterated to…

统计力学 · 物理学 2011-11-10 Andrea Gabrielli , Fabio Cecconi

In this paper we consider the two-type Moran model with $N$ individuals. Each individual is assigned a resampling rate, drawn independently from a probability distribution ${\mathbb P}$ on ${\mathbb R}_+$, and a type, either $1$ or $0$.…

概率论 · 数学 2024-12-06 Siva Athreya , Frank den Hollander , Adrian Röllin

The genetic diversity of a species is shaped by its recent evolutionary history and can be used to infer demographic events or selective sweeps. Most inference methods are based on the null hypothesis that natural selection is a weak or…

种群与进化 · 定量生物学 2013-03-05 Richard A. Neher , Oskar Hallatschek

We consider a single genetic locus with two alleles $A_1$ and $A_2$ in a large haploid population. The locus is subject to selection and two-way, or recurrent, mutation. Assuming the allele frequencies follow a Wright-Fisher diffusion and…

概率论 · 数学 2024-04-29 Wai-Tong Louis Fan , John Wakeley

The results in this paper provide new information on asymptotic properties of classical models: the neutral Kingman coalescent under a general finite-alleles, parent-dependent mutation mechanism, and its generalisation, the ancestral…

概率论 · 数学 2022-07-08 Martina Favero , Henrik Hult

We study coalescent processes conditional on the population pedigree under the exchangeable diploid bi-parental population model of \citet{BirknerEtAl2018}. While classical coalescent models average over all reproductive histories, thereby…

概率论 · 数学 2025-05-22 Frederic Alberti , Matthias Birkner , Wai-Tong Louis Fan , John Wakeley