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The metric space of phylogenetic trees defined by Billera, Holmes, and Vogtmann, which we refer to as BHV space, provides a natural geometric setting for describing collections of trees on the same set of taxa. However, it is sometimes…

种群与进化 · 定量生物学 2018-07-12 Gillian Grindstaff , Megan Owen

Given natural limitations on the length DNA sequences, designing phylogenetic reconstruction methods which are reliable under limited information is a crucial endeavor. There have been two approaches to this problem: reconstructing partial…

数据结构与算法 · 计算机科学 2008-12-10 Radu Mihaescu , Cameron Hill , Satish Rao

Distance-based phylogenetic algorithms attempt to solve the NP-hard least squares phylogeny problem by mapping an arbitrary dissimilarity map representing biological data to a tree metric. The set of all dissimilarity maps is a Euclidean…

种群与进化 · 定量生物学 2013-07-24 Ruth Davidson , Seth Sullivant

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

种群与进化 · 定量生物学 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel

Rotation distance between rooted binary trees measures the number of simple operations it takes to transform one tree into another. There are no known polynomial-time algorithms for computing rotation distance. We give an efficient,…

数据结构与算法 · 计算机科学 2018-03-19 Sean Cleary , Katherine St. John

Statistically consistent estimation of phylogenetic trees or gene trees is possible if pairwise sequence dissimilarities can be converted to a set of distances that are proportional to the true evolutionary distances. Susko et al. (2004)…

种群与进化 · 定量生物学 2015-04-28 Emily Jane McTavish , Mike Steel , Mark T. Holder

We investigate isometric embeddings of finite metric trees into $(\mathbb{R}^n,d_{1})$ and $( \mathbb{R}^n, d_{\infty})$. We prove that a finite metric tree can be isometrically embedded into $(\mathbb{R}^n,d_{1})$ if and only if the number…

度量几何 · 数学 2020-02-06 Asuman Güven Aksoy , Mehmet Kiliç , Sahin Koçak

The problem of comparing trees representing the evolutionary histories of cancerous tumors has turned out to be crucial, since there is a variety of different methods which typically infer multiple possible trees. A departure from the…

数据结构与算法 · 计算机科学 2019-04-03 Giulia Bernardini , Paola Bonizzoni , Gianluca Della Vedova , Murray Patterson

This paper addresses the basic question of how well can a tree approximate distances of a metric space or a graph. Given a graph, the problem of constructing a spanning tree in a graph which strongly preserves distances in the graph is a…

离散数学 · 计算机科学 2016-08-31 Ittai Abraham , Yair Bartal , Ofer Neiman

We study the problem of how well a tree metric is able to preserve the sum of pairwise distances of an arbitrary metric. This problem is closely related to low-stretch metric embeddings and is interesting by its own flavor from the line of…

数据结构与算法 · 计算机科学 2013-01-16 Mong-Jen Kao , Der-Tsai Lee , Dorothea Wagner

Let $G=(V,E)$ be a simple, unweighted, connected graph. Let $d(u,v)$ denote the distance between vertices $u,v$. A resolving set of $G$ is a subset $S$ of $V$ such that knowing the distance from a vertex $v$ to every vertex in $S$ uniquely…

数据结构与算法 · 计算机科学 2023-02-14 Paul Gutkovich , Zi Song Yeoh

Ancestral mixture model, proposed by Chen and Lindsay (2006), is an important model to build a hierarchical tree from high dimensional binary sequences. Mixture trees created from ancestral mixture models involve in the inferred…

数据结构与算法 · 计算机科学 2019-11-28 Justie Su-Tzu Juan , Yi-Ching Chen , Chen-Hui Lin , Shu-Chuan , Chen

An evolutionary tree is a cascade of bifurcations starting from a single common root, generating a growing set of daughter species as time goes by. Species here is a general denomination for biological species, spoken languages or any other…

定量方法 · 定量生物学 2013-08-26 Paulo Murilo Castro de Oliveira

Computational inference of dated evolutionary histories relies upon various hypotheses about RNA, DNA, and protein sequence mutation rates. Using mutation rates to infer these dated histories is referred to as molecular clock assumption.…

种群与进化 · 定量生物学 2021-01-11 Lena Collienne , Kieran Elmes , Mareike Fischer , David Bryant , Alex Gavryushkin

Graphs are interesting structures: extremely useful to depict real-life problems, extremely easy to understand given a sketch, extremely complicated to represent formally, extremely complicated to compare. Phylogeny is the study of the…

数据结构与算法 · 计算机科学 2019-01-18 Bernardo Lopo Tavares

In this study, we investigate the problem of comparing gene trees reconciled with the same species tree using a novel semi-metric, called the Path-Label Reconciliation (PLR) dissimilarity measure. This approach not only quantifies…

In this paper, we study the parallel query complexity of reconstructing biological and digital phylogenetic trees from simple queries involving their nodes. This is motivated from computational biology, data protection, and computer…

数据结构与算法 · 计算机科学 2020-09-10 Ramtin Afshar , Michael T. Goodrich , Pedro Matias , Martha C. Osegueda

Phylogenetic tree comparison metrics are an important tool in the study of evolution, and hence the definition of such metrics is an interesting problem in phylogenetics. In a paper in Taxon fifty years ago, Sokal and Rohlf proposed to…

种群与进化 · 定量生物学 2013-01-22 Gabriel Cardona , Arnau Mir , Francesc Rossello , Lucia Rotger , David Sanchez

In phylogenetics, a central problem is to infer the evolutionary relationships between a set of species $X$; these relationships are often depicted via a phylogenetic tree -- a tree having its leaves univocally labeled by elements of $X$…

数据结构与算法 · 计算机科学 2016-04-12 Julien Baste , Christophe Paul , Ignasi Sau , Celine Scornavacca

The path-difference metric is one of the oldest distances for the comparison of fully resolved phylogenetic trees, but its statistical properties are still quite unknown. In this paper we compute the mean value of the square of the…

种群与进化 · 定量生物学 2009-06-16 Arnau Mir , Francesc Rossello