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Brownian escape is key to a wealth of physico-chemical processes, including polymer folding, and information storage. The frequency of thermally activated energy barrier crossings is assumed to generally decrease exponentially with…

软凝聚态物质 · 物理学 2020-06-19 Marie Chupeau , Jannes Gladrow , Alexei Chepelianskii , Ulrich F. Keyser , Emmanuel Trizac

The probability per unit time for a thermally activated Brownian particle to escape over a potential well is in general well-described by Kramers theory. Kramers showed that the escape time decreases exponentially with increasing barrier…

统计力学 · 物理学 2023-03-22 Iman Abdoli , Hartmut Löwen , Jens-Uwe Sommer , Abhinav Sharma

The mean first passage time (MFPT) is a key metric for understanding transport, search, and escape processes in stochastic systems. While well characterized for passive Brownian particles, its behavior in active systems-such as active…

软凝聚态物质 · 物理学 2025-10-22 Sarafa A. Iyaniwura , Zhiwei Peng

Intracellular transport in living cells is often spatially inhomogeneous with an accelerated effective diffusion close to the cell membrane and a ballistic motion away from the centrosome due to active transport along actin filaments and…

统计力学 · 物理学 2021-10-22 Matthieu Mangeat , Heiko Rieger

The narrow escape problem is a first-passage problem concerned with randomly moving particles in a physical domain, being trapped by absorbing surface traps (windows), such that the measure of traps is small compared to the domain size. The…

数学物理 · 物理学 2021-09-15 Vaibhava Srivastava , Alexei Cheviakov

We study the first-passage-time (FPT) properties of an active Brownian particle under stochastic resetting to its initial configuration, comprising its position and orientation, to reach an absorbing wall in two dimensions. Coupling a…

软凝聚态物质 · 物理学 2025-04-04 Yanis Baouche , Christina Kurzthaler

The mean first passage time (MFPT) for a Brownian particle to reach a small target in cellular microdomains is a key parameter for chemical activation. Although asymptotic estimations of the MFPT are available for various geometries, these…

神经元与认知 · 定量生物学 2015-03-19 Juergen Reingruber , David Holcman

Activity significantly enhances the escape rate of a Brownian particle over a potential barrier. Whereas constant activity has been extensively studied in the past, little is known about the effect of time-dependent activity on the escape…

软凝聚态物质 · 物理学 2019-07-10 A. Scacchi , J. M. Brader , A. Sharma

During a random search, resetting the searcher's position from time to time to the starting point often reduces the mean completion time of the process. Although many different resetting models have been studied over the past ten years,…

统计力学 · 物理学 2022-09-15 Gabriel Mercado-Vásquez , Denis Boyer , Satya N. Majumdar

We study the mean first passage time (MFPT) to an absorbing target of a one-dimensional Brownian particle subject to an external potential $v(x)$ in a finite domain. We focus on the cases in which the external potential is confining, of the…

统计力学 · 物理学 2022-07-14 Gabriel Mercado-Vásquez , Denis Boyer , Satya N. Majumdar

The mean first-passage time (MFPT) is one standard measure for the reaction time in thermally activated barrier-crossing processes. While the relationship between MFPTs and phenomenological rate coefficients is known for systems that…

统计力学 · 物理学 2024-03-12 Qingyuan Zhou , Roland R. Netz , Benjamin A. Dalton

The problems of escape from metastable state in randomly flipping potential and of diffusion in fast fluctuating periodic potentials are considered. For the overdamped Brownian particle moving in a piecewise linear dichotomously fluctuating…

统计力学 · 物理学 2009-11-10 Bernardo Spagnolo , Alexander A. Dubkov , Nikolay V. Agudov

The kinetics of a variety of transport-controlled processes can be reduced to the problem of determining the mean time needed to arrive at a given location for the first time, the so called mean first passage time (MFPT) problem. The…

统计力学 · 物理学 2015-06-11 Aljaz Godec , Ralf Metzler

We develop novel numerical methods and perturbation approaches to determine the mean first passage time (MFPT) for a Brownian particle to be captured by either small stationary or mobile traps inside a bounded 2-D confining domain. Of…

数值分析 · 数学 2019-11-20 Sarafa Iyaniwura , Tony Wong , Michael J. Ward , Colin B. Macdonald

We study the first-passage-time (FPT) properties of active Brownian particles to reach an absorbing wall in two dimensions. Employing a perturbation approach we obtain exact analytical predictions for the survival and FPT distributions for…

软凝聚态物质 · 物理学 2025-03-10 Yanis Baouche , Magali Le Goff , Christina Kurzthaler , Thomas Franosch

We derive a functional equation for the mean first-passage time (MFPT) of a generic self-similar Markovian continuous process to a target in a one-dimensional domain and obtain its exact solution. We show that the obtained expression of the…

统计力学 · 物理学 2015-05-27 Vincent Tejedor , Olivier Bénichou , Ralf Metzler , Raphael Voituriez

Active matter concerns the self-organization of energy consuming elements such as motile bacteria or self-propelled colloids. A canonical example is an active Brownian particle (ABP) that moves at constant speed while its direction of…

统计力学 · 物理学 2023-06-21 Paul C Bressloff

Narrow escape and narrow capture problems which describe the average times required to stop the motion of a randomly travelling particle within a domain have applications in various areas of science. While for general domains, it is known…

统计力学 · 物理学 2022-01-14 Jason Gilbert , Alexei Cheviakov

Thermally activated escape of an over-damped particle from a metastable well under the action of a time-ramped force is studied. We express the mean first passage time (MFPT) as the solution to a partial differential equation, which we…

统计力学 · 物理学 2009-10-31 Julian Shillcock , Udo Seifert

In one-dimensional systems, the dynamics of a Brownian particle are governed by the force derived from a potential as well as by diffusion properties. In this work, we obtain the first-passage-time statistics of a Brownian particle driven…

统计力学 · 物理学 2015-11-25 Eugenio Urdapilleta
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