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A variety of natural phenomena comprises a huge number of competing reactions and short-lived intermediates. Any study of such processes requires the discovery and accurate modeling of their underlying reaction network. However, this task…

化学物理 · 物理学 2014-05-27 Paolo Elvati , Angela Violi

This paper considers optimization problems over networks where agents have individual objectives to meet, or individual parameter vectors to estimate, subject to subspace constraints that require the objectives across the network to lie in…

多智能体系统 · 计算机科学 2020-04-22 Roula Nassif , Stefan Vlaski , Ali H. Sayed

Stochastic reaction networks, which are usually modeled as continuous-time Markov chains on $\mathbb Z^d_{\ge 0}$, and simulated via a version of the "Gillespie algorithm," have proven to be a useful tool for the understanding of processes,…

概率论 · 数学 2025-07-15 David F. Anderson , Aidan S. Howells

The balance between excitation and inhibition is crucial for neuronal computation. It is observed that the balanced state of neuronal networks exists in many experiments, yet its underlying mechanism remains to be fully clarified.…

神经元与认知 · 定量生物学 2017-10-17 Qing-long L. Gu , Songting Li , Wei P. Dai , Douglas Zhou , David Cai

Reaction networks in the bulk and on surfaces are widespread in physical, chemical and biological systems. In macroscopic systems, which include large populations of reactive species, stochastic fluctuations are negligible and the reaction…

统计力学 · 物理学 2007-10-12 Baruch Barzel , Ofer Biham , Raz Kupferman

We investigate the possibility that for any given reaction rate vector $k$ associated with a network $G$, there exists another network $G'$ with a corresponding reaction rate vector that reproduces the mass-action dynamics generated by…

动力系统 · 数学 2024-09-10 Samay Kothari , Jiaxin Jin , Abhishek Deshpande

Biological regulatory networks depend upon chemical interactions to process information. Engineering such molecular computing systems is a major challenge for synthetic biology and related fields. The chemical reaction network (CRN) model…

新兴技术 · 计算机科学 2020-09-23 Cameron Chalk , Niels Kornerup , Wyatt Reeves , David Soloveichik

We study the decay process for the reaction-diffusion process of three species on the small-world network. The decay process is manipulated from the deterministic rate equation of three species in the reaction-diffusion system. The particle…

统计力学 · 物理学 2007-05-23 Kyungsik Kim , K. H. Chang , M. -K. Yum , J. S. Choi , T. Odagaki

The number of units of a network dynamical system, its size, arguably constitutes its most fundamental property. Many units of a network, however, are typically experimentally inaccessible such that the network size is often unknown. Here…

适应与自组织系统 · 物理学 2021-04-02 Hauke Haehne , Jose Casadiego , Joachim Peinke , Marc Timme

We consider a natural class of reaction networks which consist of reactions where either two species can inactivate each other (i.e., sequestration), or some species can be transformed into another (i.e., transmutation), in a way that gives…

动力系统 · 数学 2022-04-12 Gheorghe Craciun , Badal Joshi , Casian Pantea , Ike Tan

Recent algorithmic developments have enabled computers to automatically determine and prove the capacity regions of small hypergraph networks under network coding. A structural theory relating network coding problems of different sizes is…

信息论 · 计算机科学 2017-04-07 Congduan Li , Steven Weber , John MacLaren Walsh

This paper deals with identifiability of undirected dynamical networks with single-integrator node dynamics. We assume that the graph structure of such networks is known, and aim to find graph-theoretic conditions under which the state…

最优化与控制 · 数学 2018-07-24 Henk J. van Waarde , Pietro Tesi , M. Kanat Camlibel

It is useful to have complete lists of nonisomorphic chemical reaction networks (CRNs) of a given size, with or without various restrictions. One may, for example, be interested in exploring how often certain dynamical behaviours occur in…

分子网络 · 定量生物学 2017-06-01 Murad Banaji

This paper (parts I and II) provides an expository introduction to monotone and near-monotone dynamical systems associated to biochemical networks, those whose graphs are consistent or near-consistent. Many conclusions can be drawn from…

分子网络 · 定量生物学 2007-05-23 Eduardo D. Sontag

We present a computational procedure to characterize the signs of sensitivities of steady states to parameter perturbations in chemical reaction networks.

定量方法 · 定量生物学 2013-12-31 Eduardo D. Sontag

Resonator networks are ubiquitous in natural and engineered systems, such as solid-state materials, neural tissue, and electrical circuits. To understand and manipulate these networks, it is essential to characterize their building blocks,…

数据分析、统计与概率 · 物理学 2023-06-05 Viva R. Horowitz , Brittany Carter , Uriel Hernandez , Trevor Scheuing , Benjamín J. Alemán

Analog electrical networks have long been investigated as energy-efficient computing platforms for machine learning, leveraging analog physics during inference. More recently, resistor networks have sparked particular interest due to their…

新兴技术 · 计算机科学 2024-06-07 Benjamin Scellier

Understanding the emergent behavior of chemical reaction networks (CRNs) is a fundamental aspect of biology and its origin from inanimate matter. A closed CRN monotonically tends to thermal equilibrium, but when it is opened to external…

分子网络 · 定量生物学 2024-05-16 Masanari Shimada , Pegah Behrad , Eric De Giuli

We consider linear elimination of variables in steady state equations of a chemical reaction network. Particular subsets of variables corresponding to sets of so-called reactant-noninteracting species, are introduced. The steady state…

分子网络 · 定量生物学 2018-07-03 Meritxell Sáez , Carsten Wiuf , Elisenda Feliu

It is well-known that biological and social interaction networks have a varying degree of redundancy, though a consensus of the precise cause of this is so far lacking. In this paper, we introduce a topological redundancy measure for…