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Chemical Reaction Networks (CRNs) provide a useful abstraction of molecular interaction networks in which molecular structures as well as mass conservation principles are abstracted away to focus on the main dynamical properties of the…

分子网络 · 定量生物学 2020-07-31 Elisabeth Degrand , François Fages , Sylvain Soliman

Absolute concentration robustness (ACR) and concordance are novel concepts in the theory of robustness and stability within Chemical Reaction Network Theory. In this paper, we have extended Shinar and Feinberg's reaction network analysis…

分子网络 · 定量生物学 2022-09-14 Patrick Vincent N. Lubenia , Eduardo R. Mendoza , Angelyn R. Lao

The concept of the limiting step is extended to the asymptotology of multiscale reaction networks. Complete theory for linear networks with well separated reaction rate constants is developed. We present algorithms for explicit…

化学物理 · 物理学 2010-06-15 A. N. Gorban , O. Radulescu , A. Y. Zinovyev

Binomial ideals are special polynomial ideals with many algorithmically and theoretically nice properties. We discuss the problem of deciding if a given polynomial ideal is binomial. While the methods are general, our main motivation and…

组合数学 · 数学 2015-09-11 Carsten Conradi , Thomas Kahle

An important invariant of a chemical reaction network is its maximum number of positive steady states. This number, however, is in general difficult to compute. Nonetheless, there is an upper bound on this number -- namely, a network's…

分子网络 · 定量生物学 2020-12-09 Nida Obatake , Anne Shiu , Dilruba Sofia

An algorithm is given in this paper for the computation of dynamically equivalent weakly reversible realizations with the maximal number of reactions, for chemical reaction networks (CRNs) with mass action kinetics.

动力系统 · 数学 2015-03-19 Gabor Szederkenyi , Katalin M. Hangos , Zsolt Tuza

The large-scale properties of chemical reaction systems, such as the metabolism, can be studied with graph-based methods. To do this, one needs to reduce the information -- lists of chemical reactions -- available in databases. Even for the…

分子网络 · 定量生物学 2009-09-25 Petter Holme

We present the state-of-the-art single-zone nuclear reaction network WinNet that is capable of calculating the nucleosynthetic yields of a large variety of astrophysical environments and conditions. This ranges from the calculation of the…

This paper develops a mathematical framework to study signal networks, in which nodes can be active or inactive, and their activation or deactivation is driven by external signals and the states of the nodes to which they are connected via…

概率论 · 数学 2025-10-14 Bernd Heidergott , Frank den Hollander , Ines Lindner , Azadeh Parvaneh

Cycles, which can be found in many different kinds of networks, make the problems more intractable, especially when dealing with dynamical processes on networks. On the contrary, tree networks in which no cycle exists, are simplifications…

物理与社会 · 物理学 2021-04-07 Wenjun Zhang , Wei Li , Weibing Deng

Two new classes of networks are introduced that resemble small-world properties. These networks are recursively constructed but retain a fixed, regular degree. They consist of a one-dimensional lattice backbone overlayed by a hierarchical…

无序系统与神经网络 · 物理学 2008-05-29 S. Boettcher , B. Goncalves , H. Guclu

We study reaction zones in three different versions of the A+B->0 system. For a steady state formed by opposing currents of A and B particles we derive scaling behavior via renormalization group analysis. By use of a previously developed…

凝聚态物理 · 物理学 2009-10-22 Benjamin P. Lee , John Cardy

Mathematical models of stem cell differentiation are commonly based upon the concept of subsequent cell fate decisions, each controlled by a gene regulatory network. These networks exhibit a multistable behavior and cause the system to…

定量方法 · 定量生物学 2011-07-06 Christian Breindl , Daniella Schittler , Steffen Waldherr , Frank Allgöwer

To what extent do the characteristic features of a chemical reaction network reflect its purpose and function? In general, one argues that correlations between specific features and specific functions are key to understanding a complex…

统计力学 · 物理学 2012-03-22 Sang Hoon Lee , Sebastian Bernhardsson , Petter Holme , Beom Jun Kim , Petter Minnhagen

A large variety of dynamical systems, such as chemical and biomolecular systems, can be seen as networks of nonlinear entities. Prediction, control, and identification of such nonlinear networks require knowledge of the state of the system.…

最优化与控制 · 数学 2018-06-27 Aleksandar Haber , Ferenc Molnar , Adilson E. Motter

Identifying differences in networks has become a canonical problem in many biological applications. Here, we focus on testing whether two Gaussian graphical models are the same. Existing methods try to accomplish this goal by either…

统计方法学 · 统计学 2019-10-01 Sen Zhao , Stephen Ottinger , Suzanne Peck , Christine Mac Donald , Ali Shojaie

Siphons in a chemical reaction system are subsets of the species that have the potential of being absent in a steady state. We present a characterization of minimal siphons in terms of primary decomposition of binomial ideals, we explore…

交换代数 · 数学 2010-01-05 Anne Shiu , Bernd Sturmfels

Quasi-steady state (QSS) reduction is a commonly used method to lower the dimension of a differential equation model of a chemical reaction network. From a mathematical perspective, QSS reduction is generally interpreted as a special type…

动力系统 · 数学 2019-08-30 Elisenda Feliu , Christian Lax , Sebastian Walcher , Carsten Wiuf

With the rapid advancement of quantum information technology, quantum networks have become essential for supporting diverse applications, which often have stringent demands for key metrics such as fidelity and request completion time. In…

量子物理 · 物理学 2025-08-08 Yuan Li , Chen Zhang , Hao Zhang , Tao Huang , Yunjie Liu

Using a generalized random recurrent neural network model, and by extending our recently developed mean-field approach [J. Aljadeff, M. Stern, T. Sharpee, Phys. Rev. Lett. 114, 088101 (2015)], we study the relationship between the network…

无序系统与神经网络 · 物理学 2016-02-09 Johnatan Aljadeff , David Renfrew , Marina Vegué , Tatyana O. Sharpee