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Background: Large foundation models have revolutionized single-cell analysis, yet no kidney-specific model currently exists, and it remains unclear whether organ-focused models can outperform generalized models. The kidney's complex…

While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage…

定量方法 · 定量生物学 2023-09-19 Kapil Panda , Anirudh Mazumder

Efficiently quantifying renal structures can provide distinct spatial context and facilitate biomarker discovery for kidney morphology. However, the development and evaluation of the transformer model to segment the renal cortex, medulla,…

图像与视频处理 · 电气工程与系统科学 2022-03-07 Xin Yu , Yucheng Tang , Yinchi Zhou , Riqiang Gao , Qi Yang , Ho Hin Lee , Thomas Li , Shunxing Bao , Yuankai Huo , Zhoubing Xu , Thomas A. Lasko , Richard G. Abramson , Bennett A. Landman

Patients with end-stage kidney disease can expect to wait for several years before they receive a transplant, all the while their health deteriorates. How would the survival change if we managed to reduce these waiting times? To provide an…

统计方法学 · 统计学 2022-07-19 Haris Fawad , Pål Ryalen , Vasiliki Tsarpali , Kristian Heldal , Kjetil Røysland

The optimal moment to start renal replacement therapy in a patient with acute kidney injury (AKI) remains a challenging problem in intensive care nephrology. Multiple randomised controlled trials have tried to answer this question, but…

The study of matching theory has gained importance recently with applications in Kidney Exchange, House Allocation, School Choice etc. The general theme of these problems is to allocate goods in a fair manner amongst participating agents.…

计算机科学与博弈论 · 计算机科学 2020-02-10 Shyam Chandramouli , Jay Sethuraman

Renal transplantation emerges as the most effective solution for end-stage renal disease. Occurring from complex causes, a substantial risk of transplant chronic dysfunction persists and may lead to graft loss. Medical imaging plays a…

计算机视觉与模式识别 · 计算机科学 2023-05-02 Leo Milecki , Vicky Kalogeiton , Sylvain Bodard , Dany Anglicheau , Jean-Michel Correas , Marc-Olivier Timsit , Maria Vakalopoulou

This contribution presents a deep-learning method for extracting and fusing image information acquired from different viewpoints, with the aim to produce more discriminant object features for the identification of the type of kidney stones…

The shortage of nephrologists and the growing public health concern over renal failure have spurred the demand for AI systems capable of autonomously detecting kidney abnormalities. Renal failure, marked by a gradual decline in kidney…

计算机视觉与模式识别 · 计算机科学 2024-04-26 Tahmim Hossain , Faisal Sayed , Solehin Islam

We introduce partitioned matching games as a suitable model for international kidney exchange programmes, where in each round the total number of available kidney transplants needs to be distributed amongst the participating countries in a…

计算机科学与博弈论 · 计算机科学 2024-01-23 Márton Benedek , Péter Biró , Walter Kern , Dömötör Pálvölgyi , Daniël Paulusma

Chronic Kidney Disease (CKD) is a major global health issue which is affecting million people around the world and with increasing rate of mortality. Mitigation of progression of CKD and better patient outcomes requires early detection.…

Medical institutions are considering the use of LLMs in high-stakes clinical decision-making, such as organ allocation. In such sensitive use cases, evaluating fairness is imperative. However, existing evaluation methods often fall short;…

机器学习 · 计算机科学 2026-01-16 Brian Hyeongseok Kim , Hannah Murray , Isabelle Lee , Jason Byun , Joshua Lum , Dani Yogatama , Evi Micha

This work deals with a mathematical analysis of sodium's transport in a tubular architecture of a kidney nephron. The nephron is modelled by two counter-current tubules. Ionic exchange occurs at the interface between the tubules and the…

偏微分方程分析 · 数学 2020-05-18 Marta Marulli , Vuk Milisic , Nicolas Vauchelet

Among the top approaches of recent years, link prediction using knowledge graph embedding (KGE) models has gained significant attention for knowledge graph completion. Various embedding models have been proposed so far, among which, some…

人工智能 · 计算机科学 2021-06-01 Chengjin Xu , Mojtaba Nayyeri , Sahar Vahdati , Jens Lehmann

The stochastic matching problem deals with finding a maximum matching in a graph whose edges are unknown but can be accessed via queries. This is a special case of stochastic $k$-set packing, where the problem is to find a maximum packing…

数据结构与算法 · 计算机科学 2015-04-30 Avrim Blum , John P. Dickerson , Nika Haghtalab , Ariel D. Procaccia , Tuomas Sandholm , Ankit Sharma

Modelling ultrasound speckle has generated considerable interest for its ability to characterize tissue properties. As speckle is dependent on the underlying tissue architecture, modelling it may aid in tasks like segmentation or disease…

图像与视频处理 · 电气工程与系统科学 2022-06-15 Rohit Singla , Ricky Hu , Cailin Ringstrom , Victoria Lessoway , Janice Reid , Christopher Nguan , Robert Rohling

Machine learning in healthcare requires effective representation of structured medical codes, but current methods face a trade off: knowledge graph based approaches capture formal relationships but miss real world patterns, while data…

机器学习 · 计算机科学 2025-10-07 Ahmed Elhussein , Paul Meddeb , Abigail Newbury , Jeanne Mirone , Martin Stoll , Gamze Gursoy

Accurate delineation of the boundaries between the renal cortex and medulla is crucial for subsequent functional structural analysis and disease diagnosis. Training high-quality deep-learning models for layer segmentation relies on the…

图像与视频处理 · 电气工程与系统科学 2025-03-24 Junchao Zhu , Mengmeng Yin , Ruining Deng , Yitian Long , Yu Wang , Yaohong Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Accurate cell nuclei segmentation is critical for downstream tasks in kidney pathology and remains a major challenge due to the morphological diversity and imaging variability of renal tissues. While our prior work has evaluated…

We show that, in many settings, the worst-case performance of a distributed optimization algorithm is independent of the number of agents in the system, and can thus be computed in the fundamental case with just two agents. This result…

最优化与控制 · 数学 2025-11-03 Sebastien Colla , Julien M. Hendrickx