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Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…

The stomach plays a central role in digestion through coordinated muscle contractions, known as gastric peristalsis, driven by slow-wave electrophysiology. Understanding this process is critical for treating motility disorders such as…

计算工程、金融与科学 · 计算机科学 2025-12-15 Maire S. Henke , Sebastian Brandstaeter , Sebastian L. Fuchs , Roland C. Aydin , Alessio Gizzi , Christian J. Cyron

Exploring fluid-structure interactions is essential for understanding the physical principle underlying flow control in biological and man-made systems. Traditionally, we assume that the geometry is known, and from it, the solution to the…

流体动力学 · 物理学 2023-10-13 Kaare H. Jensen , Anneline H. Christensen

Cardiovascular waveforms contain information for clinical diagnosis. By "learning" and organizing the subtle change of waveform morphology from large amounts of raw waveform data, unsupervised manifold learning helps delineate a…

定量方法 · 定量生物学 2019-12-03 Shen-Chih Wang , Hau-Tieng Wu , Po-Hsun Huang , Cheng-Hsi Chang , Chien-Kun Ting , Yu-Ting Lin

The reconstruction of electrical excitation patterns through the unobserved depth of the tissue is essential to realizing the potential of computational models in cardiac medicine. We have utilized experimental optical-mapping recordings of…

定量方法 · 定量生物学 2023-09-06 Christopher D. Marcotte , Matthew J. Hoffman , Flavio H. Fenton , Elizabeth M. Cherry

The prediction of heart surface potentials using measurements from the body's surface is known as the inverse problem of electrocardiography. It is an ill-posed problem due to the multiple factors that affect the heart signal as it…

医学物理 · 物理学 2019-02-06 Joe Horvath , Lu Shien , Tommy Peng , Avinash Malik , Mark Trew , Laura Bear

In Electrical Impedance Tomography (EIT) one wants to image the conductivity distribution of a body from current and voltage measurements carried out on its boundary. In this paper we consider the underlying mathematical model, the inverse…

数值分析 · 数学 2017-04-10 Andreas Hauptmann , Matteo Santacesaria , Samuli Siltanen

This article aims to present a general analysis of a class of inverse problems that consists in recovering the elliptic parameter maps in systems of PDEs, such as the linear elastic system, from the knowledge of some of their solutions.…

偏微分方程分析 · 数学 2025-05-26 Élie Bretin , Eliott Kacedan , Laurent Seppecher

Estimating the shape and motion state of the myocardium is essential in diagnosing cardiovascular diseases.However, cine magnetic resonance (CMR) imaging is dominated by 2D slices, whose large slice spacing challenges inter-slice shape…

计算机视觉与模式识别 · 计算机科学 2023-08-29 Xiaohan Yuan , Cong Liu , Yangang Wang

Electrical impedance tomography (EIT) is a non-invasive imaging technique, capable of reconstructing images of the electrical conductivity of tissues and materials. It is popular in diverse application areas, from medical imaging to…

计算机视觉与模式识别 · 计算机科学 2024-12-24 Shuaikai Shi , Ruiyuan Kang , Panos Liatsis

In this paper we provide a representation formula for boundary voltage perturbations caused by internal conductivity inhomogeneities of low volume fraction in a simplified {\em monodomain model} describing the electric activity of the…

偏微分方程分析 · 数学 2014-12-24 Elena Beretta , M. Cristina Cerutti , Andrea Manzoni , Dario Pierotti

Slender structures, such as rods, often exhibit large nonlinear geometrical deformations even under moderate external forces (e.g., gravity). This characteristic results in a rich variety of morphological changes, making them appealing for…

软凝聚态物质 · 物理学 2024-06-24 Dezhong Tong , Zhuonan Hao , Weicheng Huang

Inferring the mechanical properties of soft tissues from measured deformations is a fundamental challenge in elastography. A rarely examined assumption underlying existing approaches is that the assumed constitutive law correctly describes…

机器学习 · 统计学 2026-04-15 Vincent C. Scholz , P. S. Koutsourelakis

This paper presents a novel intersection-based remapping method for isoparametric curvilinear meshes within the indirect arbitrary Lagrangian-Eulerian (ALE) framework, addressing the challenges of transferring physical quantities between…

数值分析 · 数学 2025-06-24 Nuo Lei , Juan Cheng , Chi-Wang Shu

Inverse problems in statistical physics are motivated by the challenges of `big data' in different fields, in particular high-throughput experiments in biology. In inverse problems, the usual procedure of statistical physics needs to be…

无序系统与神经网络 · 物理学 2017-11-07 H. Chau Nguyen , Riccardo Zecchina , Johannes Berg

Before septation processes shape its four chambers, the embryonic heart is a straight tube that spontaneously bends and twists breaking the left-right symmetry. In particular, the heart tube is subjected to a cell remodelling inducing…

软凝聚态物质 · 物理学 2020-10-05 Giulia Bevilacqua , Pasquale Ciarletta , Alfio Quarteroni

Vertex Models, as used to describe cellular tissue, have an energy controlled by deviations of each cell area and perimeter from target values. The constrained nonlinear relation between area and perimeter leads to new mechanical response.…

软凝聚态物质 · 物理学 2022-07-04 Arthur Hernandez , Michael F. Staddon , Mark J. Bowick , M. Cristina Marchetti , Michael Moshe

In this paper, we deal with the inverse problem of the shape reconstruction of inclusions in elastic bodies. The main idea of this reconstruction is based on the monotonicity property of the Neumann-to-Dirichlet operator presented in a…

数值分析 · 数学 2021-05-06 Sarah Eberle , Bastian Harrach

This study proposes an end-to-end unsupervised diffeomorphic deformable registration framework based on moving mesh parameterization. Using this parameterization, a deformation field can be modeled with its transformation Jacobian…

图像与视频处理 · 电气工程与系统科学 2022-08-30 Ameneh Sheikhjafari , Deepa Krishnaswamy , Michelle Noga , Nilanjan Ray , Kumaradevan Punithakumar