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In this paper we introduce a new mathematical model for the active contraction of cardiac muscle, featuring different thermo-electric and nonlinear conductivity properties. The passive hyperelastic response of the tissue is described by an…

组织与器官 · 定量生物学 2019-05-02 Ricardo Ruiz Baier , Alessio Gizzi , Alessandro Loppini , Christian Cherubini , Simonetta Filippi

Most existing learning-based methods for solving imaging inverse problems can be roughly divided into two classes: iterative algorithms, such as plug-and-play and diffusion methods leveraging pretrained denoisers, and unrolled architectures…

图像与视频处理 · 电气工程与系统科学 2026-03-31 Matthieu Terris , Samuel Hurault , Maxime Song , Julian Tachella

In this paper we deal with the problem of determining perfectly insulating regions (cavities) from boundary measurements in a nonlinear elliptic equation arising from cardiac electrophysiology. With minimal regularity assumptions on the…

偏微分方程分析 · 数学 2022-09-14 E. Beretta , M. C. Cerutti , D. Pierotti

The inverse conductivity problem aims at determining the unknown conductivity inside a bounded domain from boundary measurements. In practical applications, algorithms based on minimizing a regularized residual functional subject to PDE…

数值分析 · 数学 2025-10-02 Lefu Cai , Zhixin Liu , Minghui Song , Xianchao Wang

We consider the common problem setting of an elastic sphere impacting on a flexible beam. In contrast to previous studies, we analyze the modal energy distribution induced by the impact, having in mind the particular application of impact…

系统与控制 · 电气工程与系统科学 2022-07-05 Felix Gehr , Timo Theurich , Carlo Monjaraz-Tec , Johann Gross , Stefan Schwarz , Andreas Hartung , Malte Krack

In this paper, we address the challenging problem of optimal experimental design (OED) of constrained inverse problems. We consider two OED formulations that allow reducing the experimental costs by minimizing the number of measurements.…

数值分析 · 数学 2017-08-17 Lars Ruthotto , Julianne Chung , Matthias Chung

Mathematical modeling of cardiac function can provide augmented simulation-based diagnosis tool for complementing and extending human understanding of cardiac diseases which represent the most common cause of worldwide death. As the…

计算工程、金融与科学 · 计算机科学 2021-05-05 Chi Zhang , Jianhang Wang , Massoud Rezavand , Dong Wu , Xiangyu Hu

This work presents a matrix-free finite element solver for finite-strain elasticity adopting an $hp$-multigrid preconditioner. Compared to classical algorithms relying on a global sparse matrix, matrix-free solution strategies significantly…

计算工程、金融与科学 · 计算机科学 2024-12-09 Richard Schussnig , Niklas Fehn , Peter Munch , Martin Kronbichler

We introduce a new geometric approach for the homogenization and inverse homogenization of the divergence form elliptic operator with rough conductivity coefficients $\sigma(x)$ in dimension two. We show that conductivity coefficients are…

偏微分方程分析 · 数学 2009-05-13 Mathieu Desbrun , Roger D. Donaldson , Houman Owhadi

This work considers Bayesian experimental design for the inverse boundary value problem of linear elasticity in a two-dimensional setting. The aim is to optimize the positions of compactly supported pressure activations on the boundary of…

数值分析 · 数学 2023-09-06 Sarah Eberle-Blick , Nuutti Hyvönen

Inverse problems for Partial Differential Equations (PDEs) are crucial in numerous applications such as geophysics, biomedical imaging, and material science, where unknown physical properties must be inferred from indirect measurements. In…

数值分析 · 数学 2025-11-12 Dabin Park , Sanghyun Lee , Sunghwan Moon

We present a loosely coupled scheme for the numerical simulation of the cardiac electro-fluid-structure interaction problem, whose solution is typically computationally intensive due to the need to suitably treat the coupling of the…

Cardiac myocytes are the fundamental cells composing the heart muscle. The propagation of electric signals and chemical quantities through them is responsible for their nonlinear contraction and dilatation. In this study, a theoretical…

软凝聚态物质 · 物理学 2018-08-01 Pietro Lenarda , Alessio Gizzi , Marco Paggi

Existing physical model-based imaging methods for ultrasound elasticity reconstruction utilize fixed variational regularizers that may not be appropriate for the application of interest or may not capture complex spatial prior information…

图像与视频处理 · 电气工程与系统科学 2021-03-29 Narges Mohammadi , Marvin M. Doyley , Mujdat Cetin

Solving inverse problems in cardiovascular modeling is particularly challenging due to the high computational cost of running high-fidelity simulations. In this work, we focus on Bayesian parameter estimation and explore different methods…

机器学习 · 统计学 2025-12-22 Chloe H. Choi , Andrea Zanoni , Daniele E. Schiavazzi , Alison L. Marsden

This paper studies the formulation, well-posedness, and numerical solution of Bayesian inverse problems on metric graphs, in which the edges represent one-dimensional wires connecting vertices. We focus on the inverse problem of recovering…

偏微分方程分析 · 数学 2026-03-30 David Bolin , Wenwen Li , Daniel Sanz-Alonso

The inverse problem in Acousto-Electric tomography concerns the reconstruction of the electric conductivity in a domain from knowledge of the power density function in the interior of the body. This interior power density results from…

数值分析 · 数学 2020-01-09 Changyou Li , Mirza Karamehmedovic , Ekaterina Sherina , Kim Knudsen

Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…

软凝聚态物质 · 物理学 2026-05-28 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

Optimal recursive decomposition (or DR-planning) is crucial for analyzing, designing, solving or finding realizations of geometric constraint sytems. While the optimal DR-planning problem is NP-hard even for general 2D bar-joint constraint…

计算几何 · 计算机科学 2015-07-07 Troy Baker , Meera Sitharam , Menghan Wang , Joel Willoughby

We propose a one-dimensional, nonconvex elastic constitutive model with higher gradients that can predict spontaneous fracture at a critical load via a bifurcation analysis. It overcomes the problem of discontinuous deformations without…

偏微分方程分析 · 数学 2021-03-17 Phoebus Rosakis , Timothy J. Healey , Ugur Alyanak