相关论文: Generalized Hopf Bifurcation in a Cancer Model wit…
This paper investigates a class of reaction-diffusion population models defined on a bounded domain, characterized by a general time-delayed per capita growth rate and a general advection term. Notably, the growth rate encompasses both…
We propose a simple dynamic model of cancer development that captures carcinogenesis and subsequent cancer progression. A central idea of the model is to include the immune system as an extinction threshold, similar to the strong Allee…
Integrating experimental data into ecological models plays a central role in understanding biological mechanisms that drive tumor progression where such knowledge can be used to develop new therapeutic strategies. While the current studies…
This paper concerns a free boundary problem modeling tumor growth with angiogenesis and two time delays. The two delays represent the time taken for cells to undergo mitosis and modify the rate of cell loss because of apoptosis,…
This paper investigates the dynamical behaviors of a Holling type I Leslie-Gower predator-prey model where the predator exhibits an Allee effect and is subjected to constant harvesting. The model demonstrates three types of equilibrium…
The population dynamics in a modified Leslie-Gower model with an additive Allee effect are highly sensitive to both parameters and initial population densities, leading to outcomes ranging from coextinction to sustained multistable steady…
Tumors constitute a wide family of diseases kinetically characterized by the co-presence of multiple spatio-temporal scales. So, tumor cells ecologically interplay with other kind of cells, e.g. endothelial cells or immune system effectors,…
We propose a novel predator-prey model that integrate two ecologically significant mechanisms: the Allee effect in the prey population and cooperative hunting behavior among predators. Building upon the Rosenzweig-MacArthur framework, our…
This paper investigates the dynamical behaviors of a Holling type I Leslie-Gower predator-prey model where the predator exhibits an Allee effect and is subjected to constant harvesting. The model demonstrates three types of equilibrium…
In this paper, we investigate a delayed reaction-diffusion-advection equation, which models the population dynamics in the advective heterogeneous environment. The existence of the nonconstant positive steady state and associated Hopf…
In this paper, we discuss a hierarchical model, based on a Ricker competition model. The species considered are competing for resources and may be subject to an Allee effect due to mate limitation, anti-predator vigilance or aggression,…
Goodwin's model is a cornerstone in the study of dynamical systems within macroeconomics, explaining the interaction between employment ratio and wage share in a closed economy. Analogous to predator-prey dynamics in mathematical economics,…
Tumor cells develop different features to adapt to environmental conditions. A prominent example is the ability of tumor cells to switch between migratory and proliferative phenotypes, a phenomenon known as go-or-grow mechanism. It is…
Intratumor heterogeneity (ITH), referring to coexistence of different cell subpopulations in a single tumor, has been a major puzzle in cancer research for almost half a century. The lack of understanding of the underlying mechanism of ITH…
We consider the local bifurcation and global dynamics of a predator-prey model with cooperative hunting and Allee effect. For the model with weak cooperation, we prove the existence of limit cycle, heteroclinic cycle at a threshold of…
Heterogeneity is a hallmark of all cancers. Tumor heterogeneity is found at different levels -- interpatient, intrapatient, and intratumor heterogeneity. All of them pose challenges for clinical treatments. The latter two scenarios can also…
The transition between strong and weak Allee effects in prey provides a simple regime shift in ecology. A deteriorating environment changes weak Allee effects into strong ones. In this paper, we study the interplay between the functional…
This paper investigates a predator-prey system with an additive Allee effect and a generalized Holling IV functional response using a dynamical system approach. By means of a mixture of analytical and numerical procedures, we find the…
We analyze the asymptotic stability of a nonlinear system of two differential equations with delay describing the dynamics of blood cell production. This process takes place in the bone marrow where stem cells differentiate throughout…
The use of predator-prey models in theoretical ecology has a long history, and the model equations have largely evolved since the original Lotka-Volterra system towards more realistic descriptions of the processes of predation, reproduction…