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Cells of the human body have nearly identical genome but exhibit very different phenotypes that allow them to carry out specific functions and react to changes in their surrounding environment. This division of labour is achieved by…

This article is a presentation of specific recent results describing scaling limits of individual-based models. Thanks to them, we wish to relate the time-scales typical of demographic dynamics and natural selection to the parameters of the…

概率论 · 数学 2023-08-01 Aurélien Velleret

We aim at modelling the appearance of distinct tags in a sequence of labelled objects. Common examples of this type of data include words in a corpus or distinct species in a sample. These sequential discoveries are often summarised via…

统计方法学 · 统计学 2020-11-16 Alessandro Zito , Tommaso Rigon , Otso Ovaskainen , David Dunson

Convergence results for averages of independent replications of counting processes are established in a $p$-variation setting and under certain assumptions. Such convergence results can be combined with functional differentiability results…

概率论 · 数学 2019-03-12 Morten Overgaard

Under a fourth order moment condition on the branching and a second order moment condition on the immigration mechanisms, we show that an appropriately scaled projection of a supercritical and irreducible continuous state and continuous…

概率论 · 数学 2021-11-29 Matyas Barczy , Sandra Palau , Gyula Pap

We study the random times between successive cases in a transmission chain of infectious diseases with asymptomatic carriers. We derive the probability distribution of this generation time (in days) from a discrete-time epidemic model with…

种群与进化 · 定量生物学 2026-04-16 Jordi Ripoll , Joan Saldaña

Sequencing by synthesis is used in many next-generation DNA sequencing technologies. Some of the technologies, especially those exploring the principle of single-molecule sequencing, allow incomplete nucleotide incorporation in each cycle.…

基因组学 · 定量生物学 2024-05-28 Yong Kong

We propose a simple model for sample space reducing (SSR) stochastic process, where the dynamical variable denoting the size of the state space is continuous. In general, one can view the model as a multiplicative stochastic process, with a…

统计力学 · 物理学 2025-07-25 Rahul Chhimpa , Avinash Chand Yadav\

This work is a continuation of [7]. We consider a continuous-time birth-and-death process in which the transition rates have an asymptotical power-law dependence upon the position of the process. We establish rough exponential asymptotic…

概率论 · 数学 2019-11-12 A. V. Logachov , Y. M. Suhov , N. D. Vvedenskaya , A. A. Yambartsev

Count data modeling has been extensively applied in medical sciences to analyze various healthcare datasets. Numerous probability models have been developed to address diverse aspects of healthcare data. In this study, we propose a novel…

统计方法学 · 统计学 2025-09-04 Peer Bilal Ahmad , Na Elah

Compartment models with delay terms are widely used across a range of disciplines. The motivation to include delay terms varies across different contexts. In epidemiological and pharmacokinetic models, the delays are often used to represent…

动力系统 · 数学 2024-06-26 Christopher N. Angstmann , Anna V. McGann , Zhuang Xu

The deluge of single-cell data obtained by sequencing, imaging and epigenetic markers has led to an increasingly detailed description of cell state. However, it remains challenging to identify how cells transition between different states,…

At least one unusual event appears in some count datasets. It will lead to a more concentrated (or dispersed) distribution than the Poisson, the gamma, the Weibull, and the Conway-Maxwell-Poisson (CMP) can accommodate. These well-known…

应用统计 · 统计学 2021-05-07 Wanrudee Skulpakdee , Mongkol Hunkrajok

The growing popularity of wearable sensors has generated large quantities of temporal physiological and activity data. Ability to analyze this data offers new opportunities for real-time health monitoring and forecasting. However, temporal…

信号处理 · 电气工程与系统科学 2021-06-02 Nazgol Tavabi , Kristina Lerman

In this article, a new mathematical model of human population growth as an autonomous non-Markov queuing system with an unlimited number of servers and two types of applications is proposed. The research of this system was carried out a…

概率论 · 数学 2020-05-22 Mariia Nosova

In vitro cell biology experiments are routinely used to characterize cell migration properties under various experimental conditions. These experiments can be interpreted using lattice-based random walk models to provide insight into…

应用物理 · 物理学 2024-06-25 Yihan Liu , David J Warne , Matthew J Simpson

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

种群与进化 · 定量生物学 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

The population protocol model describes collections of distributed agents that interact in pairs to solve a common task. We consider a dynamic variant of this prominent model, where we assume that an adversary may change the population size…

分布式、并行与集群计算 · 计算机科学 2024-05-09 Dominik Kaaser , Maximilian Lohmann

Cell division is a process that involves many biochemical steps and complex biophysical mechanisms. To simplify the understanding of what triggers cell division, three basic models that subsume more microscopic cellular processes associated…

细胞行为 · 定量生物学 2020-03-30 Mingtao Xia , Chris D. Greenman , Tom Chou
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