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We consider a branching process with Poissonian immigration where individuals have inheritable types. At rate theta, new individuals singly enter the total population and start a new population which evolves like a supercritical,…

概率论 · 数学 2010-12-02 Mathieu Richard

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

种群与进化 · 定量生物学 2023-12-20 Cameron A. Smith , Ben Ashby

Consider a multi-dimensional supercritical branching process with offspring distribution in a parametric family. Here, each vector coordinate corresponds to the number of offspring of a given type. The process is observed under family-size…

统计理论 · 数学 2025-06-13 Gonzalo Contador , Bret Hanlon

Population genetics theory has laid the foundations for genomics analyses including the recent burst in genome scans for selection and statistical inference of past demographic events in many prokaryote, animal and plant species.…

种群与进化 · 定量生物学 2014-01-22 Aurelien Tellier , Christophe Lemaire

The entropy rates of the Wright-Fisher process, the Moran process, and generalizations are computed and used to compare these processes and their dependence on standard evolutionary parameters. Entropy rates are measures of the variation…

动力系统 · 数学 2014-03-26 Marc Harper

The paper describes a new class of capture-recapture models for closed populations when individual covariates are available. The novelty consists in combining a latent class model for the distribution of the capture history, where the class…

统计方法学 · 统计学 2021-11-08 Antonio Forcina , Francesco Bartolucci

In this paper, we propose a constraint-based modeling approach for the problem of discovering frequent gradual patterns in a numerical dataset. This SAT-based declarative approach offers an additional possibility to benefit from the recent…

人工智能 · 计算机科学 2019-03-21 Jerry Lonlac , Saïdd Jabbour , Engelbert Mephu Nguifo , Lakhdar Saïs , Badran Raddaoui

Biologists have long sought a way to explain how statistical properties of genetic sequences emerged and are maintained through evolution. On the one hand, non-random structures at different scales indicate a complex genome organisation. On…

定量方法 · 定量生物学 2018-11-01 Giampaolo Cristadoro , Mirko Degli Esposti , Eduardo G. Altmann

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

组织与器官 · 定量生物学 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

Sequential modelling entails making sense of sequential data, which naturally occurs in a wide array of domains. One example is systems that interact with users, log user actions and behaviour, and make recommendations of items of potential…

信息检索 · 计算机科学 2021-09-15 Christian Hansen

Case-cohort design, an outcome-dependent sampling design for censored survival data, is increasingly used in biomedical research. The development of asymptotic theory for a case-cohort design in the current literature primarily relies on…

统计理论 · 数学 2012-04-13 Bin Nan , Jon A. Wellner

Probabilistic model checking for systems with large or unbounded state space is a challenging computational problem in formal modelling and its applications. Numerical algorithms require an explicit representation of the state space, while…

计算机科学中的逻辑 · 计算机科学 2018-06-12 Dimitrios Milios , Guido Sanguinetti , David Schnoerr

We develop a new class of dynamic multivariate Poisson count models that allow for fast online updating and we refer to these models as multivariate Poisson-scaled beta (MPSB). The MPSB model allows for serial dependence in the counts as…

统计方法学 · 统计学 2016-09-16 Tevfik Aktekin , Nicholas G. Polson , Refik Soyer

Phylodynamics seeks to estimate effective population size fluctuations from molecular sequences of individuals sampled from a population of interest. One way to accomplish this task formulates an observed sequence data likelihood exploiting…

统计方法学 · 统计学 2016-04-27 Michael D. Karcher , Julia A. Palacios , Trevor Bedford , Marc A. Suchard , Vladimir N. Minin

We are interested in the evolving genealogy of a birth and death process with trait structure and ecological interactions. Traits are hereditarily transmitted from a parent to its offspring unless a mutation occurs. The dynamics may depend…

概率论 · 数学 2012-06-20 Sylvie Méléard , Viet Chi Tran

We consider a problem of data integration. Consider determining which genes affect a disease. The genes, which we call predictor objects, can be measured in different experiments on the same individual. We address the question of finding…

机器学习 · 统计学 2016-10-04 Xin Gao , Raymond J. Carroll

Measurements continuous in time were consistently introduced in quantum mechanics and applications worked out, mainly in quantum optics. In this context a quantum filtering theory has been developed giving the reduced state after the…

量子物理 · 物理学 2009-11-11 A. Barchielli , V. P. Belavkin

Statistical Inference is the process of determining a probability distribution over the space of parameters of a model given a data set. As more data becomes available this probability distribution becomes updated via the application of…

无序系统与神经网络 · 物理学 2022-04-28 David S. Berman , Jonathan J. Heckman , Marc Klinger

A striking feature of the marine ecosystem is the regularity in its size spectrum: the abundance of organisms as a function of their weight approximately follows a power law over almost ten orders of magnitude. We interpret this as evidence…

种群与进化 · 定量生物学 2010-09-17 Jose A. Capitan , Gustav W. Delius

We study the following model for a diploid population of constant size $N$: Every individual carries a random number of (genetic) elements. Upon a reproduction event each of the two parents passes each element independently with probability…

概率论 · 数学 2023-02-28 Peter Pfaffelhuber , Anton Wakolbinger