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We revisit the SICA (Susceptible-Infectious-Chronic-AIDS) mathematical model for transmission dynamics of the human immunodeficiency virus (HIV) with varying population size in a homogeneously mixing population. We consider SICA models…

种群与进化 · 定量生物学 2020-08-10 Cristiana J. Silva , Delfim F. M. Torres

We propose a mathematical spatiotemporal epidemic SICA model with a control strategy. The spatial behavior is modeled by adding a diffusion term with the Laplace operator, which is justified and interpreted both mathematically and…

最优化与控制 · 数学 2022-07-12 Houssine Zine , Abderrahim El Adraoui , Delfim F. M. Torres

We propose a stochastic SICA epidemic model for HIV transmission, described by stochastic ordinary differential equations, and discuss its perturbation by environmental white noise. Existence and uniqueness of the global positive solution…

种群与进化 · 定量生物学 2018-05-30 Jasmina Djordjevic , Cristiana J. Silva , Delfim F. M. Torres

We investigate the celebrated mathematical SICA model but using fractional differential equations in order to better describe the dynamics of HIV-AIDS infection. The infection process is modelled by a general functional response and the…

This study conducts a comparative analysis of stochastic and deterministic models to better understand the dynamics of the HIV epidemic across genders. By incorporating gender-specific transmission probabilities and treatment uptake rates,…

种群与进化 · 定量生物学 2025-01-30 Nuzhat Nuari Khan Rivu , Md Kamrujjaman , Shohel Ahmed

In this paper, we study the stochastic optimal control problem for the PReP vaccine in the stochastic model for HIV/AIDS with PReP. By using the stochastic maximum principle, we derive the stochastic optimal control of PReP for the…

最优化与控制 · 数学 2020-09-09 Kristina Rognlien Dahl , Jasmina Djordevic

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

种群与进化 · 定量生物学 2020-05-04 Andrew Lesniewski

In this article, we consider an HIV/AIDS epidemic model with four classes of individuals. We have discussed about basic properties of the system and found the basic reproduction number $R_0$ of the system. The stability analysis of the…

动力系统 · 数学 2023-04-18 Nouar Chorfi , Salem Abdelmalek , Samir Bendoukha

We propose a new mathematical model for the transmission dynamics of the human immunodeficiency virus (HIV). Global stability of the unique endemic equilibrium is proved. Then, based on data provided by the "Progress Report on the AIDS…

种群与进化 · 定量生物学 2017-05-30 Cristiana J. Silva , Delfim F. M. Torres

The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

种群与进化 · 定量生物学 2020-11-17 Christian Gourieroux , Yang Lu

This contribution mainly focuses on the finite horizon optimal control problems of a susceptible-infected-vaccinated(SIV) epidemic system governed by reaction-diffusion equations and Markov switching. Stochastic dynamic programming is…

最优化与控制 · 数学 2024-01-23 Zong Wang

This work focuses on optimal controls of a class of stochastic SIS epidemic models under regime switching. By assuming that a decision maker can either influence the infectivity period or isolate infected individuals, our aim is to minimize…

最优化与控制 · 数学 2021-01-12 Ky Tran , George Yin

An increasing number of control techniques are introduced to HIV infection problem to explore the options of helping clinical testing, optimizing drug treatments and to study the drug resistance situations. In such cases, complete/accurate…

最优化与控制 · 数学 2019-07-17 Fei Sun , Kamran Turkoglu

Ending the HIV/AIDS pandemic is among the Sustainable Development Goals for the next decade. In order to overcome the gap between the need for care and the available resources, better understanding of HIV epidemics is needed to guide policy…

应用统计 · 统计学 2020-09-03 Zhou Lan , Le Bao

This paper is about numerical control of HIV propagation. The contribution of the paper is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the…

系统与控制 · 计算机科学 2023-05-30 Dmitry Gromov , Ingo Bulla , Ethan O. Romero-Severson , Oana Silvia Serea

In this paper, we formulate cyber risk management and mitigation as a stochastic optimal control problem under a stochastic Susceptible-Infected-Susceptible (SIS) epidemic model. To capture the dynamics and interplay of management and…

最优化与控制 · 数学 2026-01-29 Shize Na , Zhuo Jin , Ran Xu , Hailiang Yang

A central challenge in Human Immunodeficiency Virus (HIV) public health policy lies in determining whether to universally expand treatment access, despite the risk of sub-optimal adherence and consequent drug resistance, or to adopt a more…

定量方法 · 定量生物学 2025-07-16 Ashish Poonia , Siddhartha P. Chakrabarty

We establish a stochastic HIV/AIDS model for the individuals with protection awareness and reveal how the protection awareness plays its important role in the control of AIDS. We firstly show that there exists a global positive solution for…

动力系统 · 数学 2023-03-01 Xuanpei Zhai , Wenshuang Li , Fengying Wei , Xuerong Mao

This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…

最优化与控制 · 数学 2023-04-24 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

This study utilizes mathematical models to assess progress toward achieving the UNAIDS 90-90-90 and 95-95-95 targets aimed at managing and eradicating HIV/AIDS. It contrasts stochastic and deterministic models, focusing on their utility in…

其他定量生物学 · 定量生物学 2025-03-12 Nuzhat Nuari Khan Rivu , Md Kamrujjaman , Asif Iqbal
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