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Phase response curve (PRC) is an extremely useful tool for studying the response of oscillatory systems, e.g. neurons, to sparse or weak stimulation. Here we develop a framework for studying the response to a series of pulses which are…

数据分析、统计与概率 · 物理学 2017-09-13 Vladimir Klinshov , Serhiy Yanchuk , Artur Stephan , Vladimir Nekorkin

At the level of individual neurons, various coding properties can be inferred from the input-output relationship of a cell. For small inputs, this relation is captured by the phase-response curve (PRC), which measures the effect of a small…

神经元与认知 · 定量生物学 2026-01-14 Janina Hesse , Susanne Schreiber

Regular firing neurons can be seen as oscillators. The phase-response curve (PRC) describes how such neurons will respond to small excitatory perturbations. Knowledge of the PRC is important as it is associated to the excitability type of…

神经元与认知 · 定量生物学 2010-01-05 Benjamin Torben-Nielsen , Marylka Uusisaari , Klaus M. Stiefel

The Phase Response Curve (PRC) is a tool used in neuroscience that measures the phase shift experienced by an oscillator due to a perturbation applied at different phases of the limit cycle. In this paper we present a new approach to PRCs…

动力系统 · 数学 2019-07-24 Alberto Pérez-Cervera , Tere M. Seara , Gemma Huguet

The phase-resetting curve (PRC) describes the response of a neural oscillator to small perturbations in membrane potential. Its usefulness for predicting the dynamics of weakly coupled deterministic networks has been well characterized.…

动力系统 · 数学 2015-05-13 Aushra Abouzeid , Bard Ermentrout

Synchronized neural spiking is associated with many cognitive functions and thus, merits study for its own sake. The analysis of neural synchronization naturally leads to the study of repetitive spiking and consequently to the analysis of…

神经元与认知 · 定量生物学 2017-07-19 Youngmin Park , Stewart Heitmann , G. Bard Ermentrout

The phase-response curve (PRC) is an important tool to determine the excitability type of single neurons which reveals consequences for their synchronizing properties. We review five methods to compute the PRC from both model data and…

定量方法 · 定量生物学 2010-03-29 Benjamin Torben-Nielsen , Marylka Uusisaari , Klaus M. Stiefel

The phase response curve (PRC) is an important measure representing the interaction between oscillatory elements. To understand synchrony in biological systems, many research groups have sought to measure PRCs directly from biological cells…

定量方法 · 定量生物学 2015-08-03 Kazuhiko Morinaga , Ryota Miyata , Toru Aonishi

Phase response curves are important for analysis and modeling of oscillatory dynamics in various applications, particularly in neuroscience. Standard experimental technique for determining them requires isolation of the system and…

适应与自组织系统 · 物理学 2018-09-20 Rok Cestnik , Michael Rosenblum

In this paper, we introduce and systematically study, in terms of phase response curves (PRC), the effect of a dual pulse excitation on the dynamics of an autonomous oscillator. Specifically, we test the deviations from a linear summation…

适应与自组织系统 · 物理学 2015-06-16 Giri P. Krishnan , Maxim Bazhenov , Arkady Pikovsky

The describing function (DF) and phase response curve (PRC) are classical tools for the analysis of feedback oscillations and rhythmic behaviors, widely used across control engineering, biology, and neuroscience. These tools are known to…

系统与控制 · 电气工程与系统科学 2025-11-27 Robin Wroblowski , Rodolphe Sepulchre

Many real oscillators are coupled to other oscillators and the coupling can affect the response of the oscillators to stimuli. We investigate phase response curves (PRCs) of coupled oscillators. The PRCs for two weakly coupled phase-locked…

神经元与认知 · 定量生物学 2009-11-13 Tae-Wook Ko , Bard Ermentrout

Perturbation theory is an important tool in the analysis of oscillators and their response to external stimuli. It is predicated on the assumption that the perturbations in question are "sufficiently weak", an assumption that is not always…

神经元与认知 · 定量生物学 2012-01-19 Kevin K. Lin , Kyle C. A. Wedgwood , Stephen Coombes , Lai-Sang Young

We demonstrate that the phase response curve (PRC) can be reconstructed using a weighted spike-triggered average of an injected fluctuating input. The key idea is to choose the weight to be proportional to the magnitude of the fluctuation…

适应与自组织系统 · 物理学 2009-05-18 Kaiichiro Ota , Masaki Nomura , Toshio Aoyagi

We prove that a group of injection-locked oscillators, each modelled using a nonlinear phase macromodel, responds as a single oscillator to small external perturbations. More precisely, we show that any group of injection-locked oscillators…

混沌动力学 · 物理学 2012-09-11 Jaijeet Roychowdhury

We examine the effect of the phase-resetting curve (PRC) on the transfer of correlated input signals into correlated output spikes in a class of neural models receiving noisy, super-threshold stimulation. We use linear response theory to…

神经元与认知 · 定量生物学 2015-05-13 Andrea K. Barreiro , Eric Shea-Brown , Evan L. Thilo

In this letter, we propose for the first time a method of abstracting the PPV (Perturbation Projection Vector) characteristic of the up-to-date memristor-based oscillators. Inspired from biological oscillators and its characteristic named…

新兴技术 · 计算机科学 2015-11-30 Bo Wang , Hanyu Wang , Miao Qi

The asymptotic phase $\theta$ of an initial point $x$ in the stable manifold of a limit cycle identifies the phase of the point on the limit cycle to which the flow $\phi_t(x)$ converges as $t\to\infty$. The infinitesimal phase response…

动力系统 · 数学 2018-04-13 Youngmin Park , Kendrick M. Shaw , Hillel J. Chiel , Peter J. Thomas

Neural firing is often subject to negative feedback by adaptation currents. These currents can induce strong correlations among the time intervals between spikes. Here we study analytically the interval correlations of a broad class of…

神经元与认知 · 定量生物学 2017-04-27 Tilo Schwalger , Benjamin Lindner

Oscillators are ubiquitous in nature, and usually associated with the existence of an asymptotic phase that governs the long-term dynamics of the oscillator. % We show that asymptotic phase can be estimated using a carefully chosen series…

动力系统 · 数学 2022-03-10 Simon Wilshin , Matthew D. Kvalheim , Clayton Scott , Shai Revzen
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