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The large scale behaviour of a population of cells that grow and interact through the concentration field of the chemicals they secrete is studied using dynamical renormalization group methods. The combination of the effective long-range…

细胞行为 · 定量生物学 2015-01-19 Anatolij Gelimson , Ramin Golestanian

A generically observed mechanism that drives the self-organization of living systems is interaction via chemical signals among the individual elements -- which may represent cells, bacteria, or even enzymes. Here we propose a novel…

Auto-chemotaxis, the directed movement of cells along gradients in chemicals they secrete, is central to the formation of complex spatiotemporal patterns in biological systems. Since the introduction of the Keller--Segel model, numerous…

软凝聚态物质 · 物理学 2025-11-18 Henrik Weyer , David Muramatsu , Erwin Frey

Chemical signaling is one of the ubiquitous mechanisms by which inter-cellular communication takes place at the microscopic level, particularly via chemotaxis. Such multi-cellular systems are popularly studied using continuum, mean-field…

细胞行为 · 定量生物学 2009-11-11 Ramon Grima

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

生物物理 · 物理学 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

While the role of local interactions in nonequilibrium phase transitions is well studied, a fundamental understanding of the effects of long-range interactions is lacking. We study the critical dynamics of reproducing agents subject to…

Chemotaxis is a fundamental mechanism of cells and organisms, which is responsible for attracting microbes to food, embryonic cells into developing tissues, or immune cells to infection sites. Mathematically chemotaxis is described by the…

偏微分方程分析 · 数学 2020-09-30 Erika Hausenblas , Debopriya Mukherjee , Thanh Tran

We study the stationary Keller--Segel chemotaxis models with logistic cellular growth over a one-dimensional region subject to the Neumann boundary condition. We show that nonconstant solutions emerge in the sense of Turing's instability as…

偏微分方程分析 · 数学 2016-04-19 Qi Wang , Jingda Yan , Chunyi Gai

Chemotaxis allows single cells to self-organize at the population level, as classically described by Keller-Segel models. We show that chemotactic aggregation can be understood using a generalized Maxwell construction based on the balance…

软凝聚态物质 · 物理学 2025-11-18 Henrik Weyer , David Muramatsu , Erwin Frey

We introduce stochastic models of chemotaxis generalizing the deterministic Keller-Segel model. These models include fluctuations which are important in systems with small particle numbers or close to a critical point. Following Dean's…

统计力学 · 物理学 2009-09-01 Pierre-Henri Chavanis

For the first time the phenomenon of cellular structure coarsening are consistently analysed from the positions of kinetic, hydrodynamic and stochastodynamic theories of nonequilibrium statistical systems. Thereby micro-, meso- and…

凝聚态物理 · 物理学 2015-06-25 S. B. Goryachev

Bacterial cells navigate around their environment by directing their movement along chemical gradients. This process, known as chemotaxis, can promote the rapid expansion of bacterial populations into previously unoccupied territories.…

种群与进化 · 定量生物学 2022-06-08 Avaneesh V. Narla , Jonas Cremer , Terry Hwa

Collective motion of chemotactic bacteria as E. Coli relies, at the individual level, on a continuous reorientation by runs and tumbles. It has been established that the length of run is decided by a stiff response to a temporal sensingof…

偏微分方程分析 · 数学 2018-08-15 Benoît Perthame , Shugo Yasuda

A Keller-Segel model describes macroscopic dynamics of bacterial colonies and biological cells. Bacteria secret chemical which attracts other bacteria so that they move towards chemical gradient creating nonlocal attraction between…

斑图形成与孤子 · 物理学 2010-05-18 Pavel M. Lushnikov

Cells coexist together in colonies or as tissues. Their behaviour is controlled by an interplay between intercellular forces and biochemical regulation. We develop a simple model of the cell cycle, the fundamental regulatory network…

生物物理 · 物理学 2021-08-04 Jintao Li , Simon K. Schnyder , Matthew S. Turner , Ryoichi Yamamoto

Bacterial chemotaxis in Escherichia coli is a canonical system for the study of signal transduction. A remarkable feature of this system is the coexistence of precise adaptation in population with large fluctuating cellular behavior in…

分子网络 · 定量生物学 2019-08-19 Thierry Emonet , Philippe Cluzel

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

生物物理 · 物理学 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

统计力学 · 物理学 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using flourrescence imaging have shown that,…

统计力学 · 物理学 2008-11-29 Hui Wang , Ned S. Wingreen , Ranjan Mukhopadhyay

The rate at which individual bacterial cells grow depends on the concentrations of cellular components such as ribosomes and proteins. These concentrations continuously fluctuate over time and are inherited from mother to daughter cells,…

种群与进化 · 定量生物学 2024-08-21 Yaïr Hein , Farshid Jafarpour
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