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Research in epidemiology often focusses on designing interventions that result in the number of infected individuals asymptotically approaching zero, without considering that this number may peak at high values during transients. Recent…

最优化与控制 · 数学 2020-03-24 Willem Esterhuizen , Tim Aschenbruck , Jean Lévine , Stefan Streif

We propose a model predictive control (MPC) approach for minimising the social distancing and quarantine measures during a pandemic while maintaining a hard infection cap. To this end, we study the admissible and the maximal robust…

Metapopulation epidemic models describe epidemic dynamics in networks of spatially distant patches connected with pathways for migration of individuals. In the present study, we deal with a susceptible-infected-recovered (SIR)…

物理与社会 · 物理学 2019-08-22 Akari Matsuki , Gouhei Tanaka

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

应用统计 · 统计学 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

种群与进化 · 定量生物学 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

We consider the SEIR compartmental epidemic model subject to state and input constraints (a cap on the proportion of infectious individuals and limits on the allowed social distancing and quarantining measures, respectively). We present a…

最优化与控制 · 数学 2024-06-11 Willem Esterhuizen , Philipp Sauerteig , Stefan Streif , Karl Worthmann

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

应用统计 · 统计学 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

We study the impact of parameter estimation and state measurement errors on a control framework for optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic…

系统与控制 · 电气工程与系统科学 2024-08-08 Baike She , Lei Xin , Shreyas Sundaram , Philip E. Paré

Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…

种群与进化 · 定量生物学 2023-08-03 Jasmin Nunuvero , Angelique Santiago , Moshe Cohen , Anca Radulescu

The adoption of prophylaxis attitudes, such as social isolation and use of face masks, to mitigate epidemic outbreaks strongly depends on the support of the population. In this work, we investigate a susceptible-infected-recovered (SIR)…

物理与社会 · 物理学 2022-10-05 Diogo H. Silva , Celia Anteneodo , Silvio C. Ferreira

Exploiting the power of the expectation operator and indicator (or Bernoulli) random variables, we present the exact governing equations for both the SIR and SIS epidemic models on \emph{networks}. Although SIR and SIS are basic epidemic…

动力系统 · 数学 2014-02-10 Piet Van Mieghem

This study investigates the influence of different types of non-pharmaceutical interventions (NPIs) on epidemic progression using SIR compartmental models. We analyze the optimization of two distinct targets: the final epidemic size and the…

种群与进化 · 定量生物学 2026-04-10 Eric Rozán , Marcelo N Kuperman , Sebastián Bouzat

In the recent COVID-19 pandemic we assisted at a sequence of epidemic waves intertwined by anomalous fade-outs with periods of low but persistent epidemic prevalence. These long-living epidemic states complicate epidemic control and…

物理与社会 · 物理学 2025-08-27 Javier Aguilar , Beatriz Arregui García , Raúl Toral , Sandro Meloni , Jose J. Ramasco

The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

种群与进化 · 定量生物学 2020-11-17 Christian Gourieroux , Yang Lu

This paper considers a stochastic SIR (susceptible$\to$infective$\to$removed) epidemic model in which individuals may make infectious contacts in two ways, both within `households' (which for ease of exposition are assumed to have equal…

概率论 · 数学 2015-03-13 Frank Ball , David Sirl , Pieter Trapman

Contagious processes, such as spread of infectious diseases, social behaviors, or computer viruses, affect biological, social, and technological systems. Epidemic models for large populations and finite populations on networks have been…

最优化与控制 · 数学 2020-04-14 Renato Pagliara , Naomi E. Leonard

A probabilistic approach to the epidemic evolution on realistic social-contact networks allows for characteristic differences among subjects, including the individual number and structure of social contacts, and the heterogeneity of the…

社会与信息网络 · 计算机科学 2022-02-11 Jan B. Broekaert , Davide La Torre , Faizal Hafiz

We consider a behavioral-feedback SIR epidemic model, in which the infection rate depends in feedback on the fractions of susceptible and infected agents, respectively. The considered model allows one to account for endogenous adaptation…

系统与控制 · 电气工程与系统科学 2026-02-11 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

We investigate final outcome properties of an SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a population of large sub-communities in which there is stronger disease transmission within the communities than…

概率论 · 数学 2024-04-08 Frank Ball , David Sirl , Pieter Trapman
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